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대한소화기학회> 대한소화기학회지> 과민성장증후군 환자에 대한 대변 미생물총 이식 치료의 반응 예측: 장내 미생물총의 측면에서

KCI등재

과민성장증후군 환자에 대한 대변 미생물총 이식 치료의 반응 예측: 장내 미생물총의 측면에서

Therapeutic Response Prediction of Fecal Microbiota Transplantation for Patients with Irritable Bowel Syndrome: In Terms of Gut Microbiota

김대성 ( Dae Sung Kim )
  • : 대한소화기학회
  • : 대한소화기학회지 80권5호
  • : 연속간행물
  • : 2022년 11월
  • : 237-239(3pages)
대한소화기학회지

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UCI(KEPA)

간행물정보

  • : 의약학분야  > 내과학
  • : KCI등재
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  • : 월간
  • : 1598-9992
  • : 2233-6869
  • : 학술지
  • : 연속간행물
  • : 1968-2022
  • : 5883


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80권6호(2022년 12월) 수록논문
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KCI등재

1소화기내과 환자와 의사의 관계와 환자 경험

저자 : 김은선 ( Eun Sun Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 241-246 (6 pages)

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As clinical practices change to involve patients more actively and patient feedback becomes integrated into ongoing measures of quality, patients themselves, along with their families and friends, could play a creative part in crafting solutions to improve patient's experience. We could convene focus groups of patients to help examine varied aspects of our practice, ranging from the flow through our offices to the way we communicate. They could work with us, helping us make choices and set priorities. Incorporating both patients' perceptions and suggestions for change can address clinically significant aspects of the patient experience, foster the involvement of patients in their care, and help assess and improve the quality of the care we deliver. The electronic medical record and secure patient portals increasingly provide a powerful opportunity to actively promote patient involvement. Improving of patient's experience can help doctors draw closer to their patients and restore and strengthen public trust. It can both improve the quality of our care and add to the joy of being a doctor. Our purpose is to improve patients' treatment results, and through this, to feel rewarding as a doctor as a professional and to continue working as a doctor. To this end, improving the doctor-patient relationship through improving patient experience can be a key factor. (Korean J Gastroenterol 2022;80:241-246)

KCI등재

2새로운 칼륨 경쟁적 위산분비 차단제

저자 : 최윤진 ( Yoon Jin Choi )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 247-253 (7 pages)

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Proton pump inhibitors (PPIs) have several limitations to their efficacy including insufficient acid suppression, slow onset of action, and variable efficacy among patients due to CYP2C19 metabolism. Potassium-competitive acid blockers inhibit H+-K+-ATPase in a reversible and K+-competitive manner, are novel acid suppressive drugs with rapid onset of action, meal independence, and prolonged control of intragastric acidity compared to PPIs. Potassium-competitive acid blockers exhibited non-inferior therapeutic efficacies on reflux esophagitis, gastric ulcers, and Helicobacter pylori eradication. The review is focused on the unmet needs across the acid-related diseases and recent updates on clinical studies using vonoprazan and tegoprazan. (Korean J Gastroenterol 2022;80:247-253)

KCI등재

3고식적 항문내압검사를 이용하여 건강한 대상자에서 연령과 성별이 항문 직장 기능에 미치는 효과에 대한 연구

저자 : 김희진 ( Hee Jin Kim ) , 김나영 ( Nayoung Kim ) , 최용훈 ( Yonghoon Choi ) , 이종찬 ( Jongchan Lee ) , 윤혁 ( Hyuk Yoon ) , 신철민 ( Cheol Min Shin ) , 박영수 ( Young Soo Park ) , 이동호 ( Dong Ho Lee ) , 김혜랑 ( Hye Rang Kim ) , 강성범 ( Sung-bum Kang )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 254-262 (9 pages)

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Background/Aims: Anorectal functions are influenced by gender and age. This study sought to define the normal anorectal pressure values measured with conventional anorectal manometry (ARM) and to evaluate the effects of age and gender on anorectal function in asymptomatic subjects.
Methods: Conventional ARM was used to measure the anorectal pressures of 164 asymptomatic healthy subjects, including 86 males and 76 females.
Results: The resting anal pressures of males and females aged >60 years were significantly lower than those ≤60 years (males, 44.09±14.22 vs. 57.45±17.69, p<0.001; females, 44.09±14.22 vs. 57.45±17.69, p<0.001). The anal high-pressure zone was significantly lower in older males than in younger males (2.42±0.93 vs. 2.82±0.739, p=0.048). In both age groups (<60 and ≥60 years), the anal squeezing pressures of males were significantly higher than those of females (<60 years old, 168.40±75.94 vs. 119.15±57.53, p=0.001; ≥60 years, 149.61±64.68 vs. 101.3±54.92, p=0.006).
Conclusions: The normal anorectal pressure values measured with ARM in males and females were different. Older males and females had lower anal resting pressures than those of the younger subjects, but squeezing pressure was not affected by age. (Korean J Gastroenterol 2022;80:254-261)

KCI등재

4급성 봉소염성 식도염의 합병증으로 발생한 식도 내 농양의 내시경적 배액술 후 발생한 식도내강의 협착: 증례 보고

저자 : 김민지 ( Min Ji Kim ) , 유대곤 ( Dae Gon Ryu ) , 박수범 ( Su Bum Park ) , 최철웅 ( Cheol Woong Choi ) , 김형욱 ( Hyung Wook Kim ) , 김수진 ( Su Jin Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 262-266 (5 pages)

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Esophageal abscess caused by acute phlegmonous esophagitis is rare but life-threatening. Rapid abscess drainage is an important part of the treatment, and endoscope-assisted intra-luminal abscess drainage is frequently performed. Although endoscopic drainage is less invasive than surgery, it has the potential to cause esophageal stricture as a complication. We present a rare case of esophageal stricture as a complication of intra-luminal drainage and evaluate a method to minimize the incidence of esophageal stricture complications. (Korean J Gastroenterol 2022;80:262-266)

KCI등재

5크론병으로 인한 다발성 누공을 동반한 둔부와 천골전 농양

저자 : 좌희정 ( Hui Jeong Jwa ) , 송현주 ( Hyun Joo Song ) , 전호경 ( Hogyung Jun ) , 김성택 ( Seong Taeg Kim ) , 부선진 ( Sun-jin Boo ) , 김흥업 ( Heung Up Kim ) , 이동현 ( Donghyoun Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 267-272 (6 pages)

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The abscess is a common complication of Crohn's disease (CD), with the perianal form more frequent than gluteal or presacral which is relatively rare. There are few case reports of gluteal abscess combined with presacral abscess caused by CD and the treatment has not been established. A 21-year-old male was admitted with right buttock and lower back pain with a duration of 3 months. He had a history of CD in the small intestine diagnosed 10 months previously. He had poor compliance and had not returned for follow-up care during the previous 6 months. Abdominopelvic CT indicated newly developed multiple abscess pockets in right gluteal region, including piriformis muscle and presacral space. Additionally, fistula tracts between small bowel loops and presacral space were observed. Patient's CD was moderate activity (273.12 on the Crohn's Disease Activity Index [CDAI]). Treatment was started with piperacillin/ tazobactam antibiotic but patient developed a fever and abscess extent was aggravated. Therefore, surgical incision and drainage was performed and 4 Penrose drains were inserted. Patient's pain and fever were resolved following surgery. Infliximab was then administered for the remaining fistulas. After the induction regimen, multiple fistula tracts improved and patient went into remission (CDAI was -0.12). (Korean J Gastroenterol 2022;80:267-272)

KCI등재

6진행성 위암에서 출혈 예방을 위한 5-FU 종양주위투여에 대한 선행 연구

저자 : 김남희 ( Nam-hee Kim ) , 박정호 ( Jung Ho Park ) , 구동회 ( Dong-hoe Koo ) , 정윤숙 ( Yoon Suk Jung ) , 양정윤 ( Jeong-yoon Yang ) , 이희영 ( Hee-young Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 273-280 (8 pages)

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Five-FU is a potent chemotherapeutic agent for suppressing endothelial cell growth. The purpose of this study was to investigate the usefulness of local peritumor injection of 5-FU for patients with advanced gastric cancer (AGC) for the prevention of anemia. Between January 2020 and January 2022, patients aged 18 years or older with AGC and moderate anemia were included. A total of 200 mg of 5-FU was injected per session at ten points of the lesion (20 mg at each point) every 7 days for 4 to 12 weeks. Patients received a blood test for toxicity at every cycle. From one of these patients, endoscopic biopsy specimens were taken from gastric cancer before and after injecting 5-FU for immunostaining. A total of five AGC patients participated in this study. For most patients, hemoglobin levels were maintained without transfusions during 5-FU injection, and expression levels of thrombospondin-1 was increased after injection compared to those before injection. Blood test results during 5-FU injection showed no significant change in serum glutamic oxalacetic transaminase/glutamic pyruvic transaminase, total bilirubin, or creatinine level. The results of this study showed the possibility of local peritumor 5-FU injection as a treatment for relieving anemia of patients with gastric cancer. (Korean J Gastroenterol 2022;80: 273-280)

KCI등재

7상행결장 정맥류에 의한 하부위장관 출혈

저자 : 김상훈 ( Sang Hoon Kim ) , 조혜기 ( Hyeki Cho )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 281-284 (4 pages)

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8중등도 이상의 궤양성 대장염의 내시경적 반응 및 관해의 평가에서 장초음파의 유용성

저자 : 김동현 ( Dong Hyun Kim ) , 김현수 ( Hyun-soo Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 6호 발행 연도 : 2022 페이지 : pp. 285-287 (3 pages)

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KCI등재

1국내 내시경 수련의 현주소와 향후 방향

저자 : 주영은 ( Young-eun Joo )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 207-210 (4 pages)

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The training of trainees to perform endoscopies is challenging. There is no standardized training program in Korea. Trainees usually learn to perform endoscopies under the supervision of an educator, an expert endoscopist. However, most of educators have never received formal training. For high quality and effecting training, formal training program for educators is needed. Also, specific assessment tools measuring performance and improving training are required. The use of simulators for acquiring, maintaining, and assessing skills in endoscopy has grown over the past decade. Many data suggest that simulation training may accelerate the acquisition of specific technical skills in endoscopy early in training. If we include education using simulators in basic endoscopy education, it will be of great help to shorten the endoscopy training time and improve the endoscopy training environment. A significant portion of medical lawsuits against gastroenterologists in Korea are related to complications related to sedation. Therefore, endoscopy education should include contents related to sedation education. Also, systematic and thorough education program along with assessment tool measuring true competence of sedation in endoscopy is needed. Changes should be made at all levels to improve our endoscopy training system. (Korean J Gastroenterol 2022;80:207-210)

KCI등재

2소화기내과 전공의 및 전임의를 위한 복부초음파 교육

저자 : 천영국 ( Young Koog Cheon ) , 김영중 ( Youngjung Kim ) , 이준성 ( Joon Seong Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 211-216 (6 pages)

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Ultrasound (US) is an essential diagnostic tool in almost every medical area. Therefore, abdominal US education for internal medicine residents was mandated by the Korean Association of Internal Medicine. However, US education for physicians has been conducted only in some university hospitals that directly perform abdominal US examinations in internal medicine, or some education is provided with the help of radiologists. US technology continues to become increasingly widespread, portable, and miniaturized. Furthermore, point-of-care US, i.e., US executed at the patient's bedside to obtain real-time objective information with diagnostic and clinical monitoring purposes or to guide invasive procedures, has been incorporated in many specialties. Despite the increasing role of US, there is no systemized abdominal US education program. Therefore, the authors are trying to develop a structured abdominal US education program through cooperation with related US organizations. (Korean J Gastroenterol 2022;80:211-216)

KCI등재

3소화기내과 전공의 및 전임의 수련 교육의 현실과 개선방안

저자 : 정우철 ( Woo Chul Chung )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 217-220 (4 pages)

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The Korean Society of Gastroenterology (KSG) and the Korean Society of Gastrointestinal Endoscopy (KSGE) have tried to promote high-quality patient care, and safety in the field of gastrointestinal (GI) diseases. In 2017, the training guidelines for GI fellows have been made, and the education board of KSGE revised 2 year- program of GI fellows. The guideline includes the total number of assigned patients, the number of GI endoscopy procedures, attendance of academic conferences, and research presentations. The traditional training model of GI fellowship is known as an “apprenticeship”. Unfortunately, it might increase confusion between what trainees are observing and prior information. Now, practical hands-on training system using simulator helps to provide a support program for GI fellowship education. In order to facilitate training program, trainers will need to carefully plan the teaching. Therefore, it improves knowledge and performance for trainers. What we should keep in mind is that this hands-on program has the goal of making a good gastroenterologist, not just making an endoscopist. At same time, the application of cognitive education in GI fellow training must be performed. On the other side, the privileging and credentialing for endoscopic subspecialty should be made. The provision of benefits could serve as an important foundation for maintaining GI specialist board system. (Korean J Gastroenterol 2022;80:217-220)

KCI등재

4십이지장스텐트 삽입 중 발생한 위천공

저자 : 고성우 ( Sung Woo Ko ) , 소훈섭 ( Hoonsub So ) , 방성조 ( Sung Jo Bang )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 221-224 (4 pages)

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Gastric outlet obstruction is a major symptom in patients with advanced pancreatic cancer. Endoscopic intervention is often challenging in severe strictures because the guidewire cannot pass beyond the stricture. Sometimes, the air itself cannot pass beyond the stricture, which can result in a severely distended stomach. Such a stomach is vulnerable to excessive air insertion or mechanical stress during endoscopic procedures, and endoscopists may encounter a higher rate of complications. Gastric perforation is rare but could be fatal. However, endoscopic management can show a favorable result if the perforation is noticed early. The authors report a case of the perforation of a gastric tear during duodenal stent insertion in a patient with a gastric outlet obstruction. (Korean J Gastroenterol 2022;80:221-224)

KCI등재

5위궤양으로 발현된 콜라겐 위십이지장염

저자 : 최인형 ( In Hyoung Choi ) , 조유경 ( Yu Kyung Cho ) , 박준영 ( Jun Young Park ) , 강동훈 ( Donghoon Kang ) , 박재명 ( Jae Myung Park ) , 최명규 ( Myung-gyu Choi )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 225-228 (4 pages)

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Collagenous gastroduodenitis is a rare gastrointestinal disease diagnosed histologically by subepithelial collagen deposition in the lamina propria. Its clinical presentation is diverse. The authors encountered a 17-year-old female patient who complained of epigastric pain. Endoscopy revealed several deep ulcers in the gastric body. The gastric mucosa around the ulcer showed diffuse fine nodularity in the shape of cobblestones with open-type atrophy. The duodenal mucosa showed nodular lesions similar to those of the gastric mucosa. The gastric ulcer healed completely with proton pump inhibitor treatment. The patient was followed up, showing no remarkable mucosal change of stomach or duodenum for several years. Collagenous gastroduodenitis was diagnosed by repeated histologic examinations. This paper reports a rare case of chronic collagen gastritis with deep gastric ulcer and its long-term clinical progress. (Korean J Gastroenterol 2022;80:225-228)

KCI등재

6비위관 자극으로 인한 대동맥식도누공: 증례 보고

저자 : 이상민 ( Sangmin Lee ) , 김육 ( Yook Kim ) , 김기배 ( Ki Bae Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 229-232 (4 pages)

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A 91-year-old woman who presented with melena and hypovolemic shock visited the emergency room. She received enteral nutrition by nasogastric tube in a bedridden state due to hip surgery. Gastroscopy initially suggested a simple ulcer that occurred after a nasogastric tube was placed for a long time, but the ulcer was deep, and the amount of instantaneous bleeding was considerable. Therefore, an aortoesophageal fistula was suspected. Angiography was performed instead of endoscopic hemostasis, followed by thoracic endovascular aortic repair (TEVAR). After the TEVAR procedure, the patient recovered without further gastrointestinal bleeding. Prompt judgment and communication between the endoscopist and the interventional physician are important for successful hemostasis in an aortoenteric fistula patient. (Korean J Gastroenterol 2022;80:229-232)

KCI등재

7간세포암종 환자에서 경동맥화학색전술 후 발생한 리피오돌 유도 폐렴

저자 : 남희철 ( Heechul Nam )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 233-236 (4 pages)

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KCI등재

8과민성장증후군 환자에 대한 대변 미생물총 이식 치료의 반응 예측: 장내 미생물총의 측면에서

저자 : 김대성 ( Dae Sung Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 80권 5호 발행 연도 : 2022 페이지 : pp. 237-239 (3 pages)

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