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대한한방신경정신과학회> 동의신경정신과학회지> 불안에 대한 한의정신요법과 중의정신요법의 비교고찰: 임상연구를 중심으로

KCI등재

불안에 대한 한의정신요법과 중의정신요법의 비교고찰: 임상연구를 중심으로

Comparison of Korean Medicine Psychotherapy and Traditional Chinese Medicine Psychotherapy for Anxiety: Focusing on Clinical Studies

이지원 ( Ji-won Lee ) , 황인준 ( In-jun Hwang ) , 박민령 ( Min-ryeong Park ) , 권찬영 ( Chan-young Kwon )
  • : 대한한방신경정신과학회
  • : 동의신경정신과학회지 33권3호
  • : 연속간행물
  • : 2022년 09월
  • : 301-316(16pages)
동의신경정신과학회지

DOI


목차

Ⅰ. 서론
Ⅱ. 방법
Ⅲ. 결과
Ⅳ. 고찰
Ⅴ. 결론
REFERENCES

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초록 보기

Objectives: To compare Korean medicine (KM) and traditional Chinese medicine (TCM) psychotherapy for anxiety.
Methods: Databases including MEDLINE (via PubMed), EMBASE (via Elsevier), Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, and Oriental Medicine Advanced Searching Integrated System were comprehensively searched. Prospective clinical studies on KM or TCM psychotherapy for patients with anxiety disorder or individuals with elevated anxiety levels published up to August 3, 2022 were reviewed. Psychotherapy was divided into counselling, art therapy, and meditation according to its characteristics.
Results: A total of 12 clinical studies were reviewed, including nine randomized controlled trials. The most common disorder investigated was post-traumatic stress disorder. Ten studies used TCM psychotherapy and two used KM psychotherapy. As for differences between TCM psychotherapy and KM psychotherapy, TCM psychotherapy utilized pattern identification in the procedure more actively than KM psychotherapy. In addition, some TCM studies have attempted to directly converge Western psychotherapy (i.e., hypnosis) and Eastern psychotherapy (i.e., Taoin qigong therapy). In the case of KM psychotherapy, there was an attempt to incorporate psychotherapy with Sasang constitutional medicine. Reported effects of TCM psychotherapy and KM psychotherapy on anxiety were positive.
Conclusions: Research status of KM psychotherapy and TCM psychotherapy for anxiety was investigated, revealing some of their characteristics, commonalities, and differences. Findings of this review have the potential to provide a clue to the development of conventional KM psychotherapy and new medical technology for KM psychotherapy.

UCI(KEPA)

간행물정보

  • : 의약학분야  > 기초한의학
  • : KCI등재
  • :
  • : 계간
  • : 1226-6396
  • : 2234-4942
  • : 학술지
  • : 연속간행물
  • : 1990-2022
  • : 1050


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33권4호(2022년 12월) 수록논문
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KCI등재

1틱장애 아동 보호자의 일상 및 한의치료 이용 경험에 대한 질적 연구

저자 : 윤석인 ( Seok-in Yoon ) , 서효원 ( Hyo-weon Suh ) , 이미선 ( Misun Lee ) , 홍성규 ( Sunggyu Hong ) , 정선용 ( Sun-yong Chung )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 361-376 (16 pages)

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Objectives: To understand experiences of daily life and Korean medicine treatment process and perspectives of caregivers caring for children with tic disorder.
Methods: A semi-structured interview was conducted with caregivers of patients under 13 years who were experiencing Korean medicine treatment for tic disorder. A total of five participants were interviewed. The analysis was performed according to a four-step phenomenological method.
Results: The following four components were derived from the experience of caring for children with tic disorder: general perception of tics, negative emotions caused by tics, social deprivation, and living with a child with tics. The following four components were derived from Korean medicine treatment experience for tic disorders: criteria for selecting treatment, awareness of Korean medicine, treatment experience in Korean medicine, and what needs to be improved.
Conclusions: According to results of this study, caregivers caring for children with tic disorder experienced negative emotions such as frustration, guilt, and anxiety. They also experienced social deprivation such as stigma and prejudice. Korean medicine treatment can be an effective alternative for improving symptoms of tic disorders. The application of insurance benefits to Korean medicine is needed for patients and caregivers to autonomously choose treatment.

KCI등재

2CP 기반 정신 평가 및 진단을 위한 심리검사의 활용

저자 : 홍성규 ( Sunggyu Hong ) , 이현우 ( Hyun Woo Lee ) , 정선용 ( Sun-yong Chung ) , 김종우 ( Jong-woo Kim )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 377-388 (12 pages)

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Objectives: For diagnosis and evaluation, evaluation tools are needed. Various tools can be used to diagnose and evaluate mental disorders. Among them, psychological tests are widely used. For Korean Standard Classification of Diseases (KCD) diagnosis, psychological tests are also required. Currently developed critical pathway (CP) presented tools for diagnosis and evaluation of mental disorders. The CP suggests the use of tools based on the Clinical Practice Guideline (CPG). Therefore, CPG-based tools should be able to be used in the clinical scene of Korean Medicine for diagnosing and evaluating mental disorders according to CP.
Methods: Tools suggested by CPs are summarized. The degree of utilization of tools in CPGs is also summarized. A review was conducted by Korean Medicine neuropsychiatrist experts on tools and user's usage plan.
Results: As a result, developed CPs suggested using 19 tools for anxiety disorder, 13 tools for insomnia), 12 tools for Hwabyeong, and 9 tools for dementia. In CPG, 48, 34, 44, and 44 tools were used for anxiety disorder, insomnia, Hwabyeong, and dementia, respectively. Among tools presented in CP, HAM-A, HAM-D, CGI, SAS, and TESS for anxiety disorder, CPG, ISI, and PSQI for insomnia disorder, CPG, STAI, and STAXI for Hwabyeong were frequently used in CPG. For dementia CPG, MoCA, MMSE, HDS, ADL, and ADAS-cog were frequently used. Among them, MoCA, ADL, and ADAS-cog were suggested tools in CP.
Conclusions: As a result of analyzing tools suggested and used in the developed CPs and CPGs, it was verified that various tools were used in each study. Most of them were symptom and behavioral evaluation scales. Therefore, symptoms and behavior evaluation scales used more frequently should be able to be used in the clinical scene of Korean Medicine.

KCI등재

3Efficacy and Safety of Banhahubak-Tang for Depression Treatment: Study Protocol for a Randomized, Waitlist-Controlled Trial

저자 : Seung-ho Lee , Yunna Kim , Dohyung Kwon , Seung-hun Cho

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 389-400 (12 pages)

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Objectives: Depression is a highly prevalent disease, and the market for antidepressant drugs continues to grow at a steady rate. Although current antidepressants are reported to be effective, because of their low remission rate and side effects, new antidepressants are needed. The use of Banhahubaktang (BHT) to treat the symptoms of depression is supported by experimental evidence. The proposed study will evaluate the efficacy and safety of BHT in treating depression.
Methods: A randomized, waitlist-controlled, parallel clinical trial will be conducted to assess the efficacy of BHT in depression. A total of 84 participants with depression will be randomized into the intervention group or waitlist-control group at a 1:1 ratio. Patients in the intervention group will be administered BHT three times a day for four weeks and followed up for four more weeks after therapy completion. Patients in the waitlist-control group will undergo the same intervention and follow-up after a four-week waiting period. The primary outcome is change in the Korean version of the Hamilton Depression Rating Scale (K-HDRS) scores for major depressive disorders after four weeks. The secondary outcomes include scores on the K-HDRS, Korean Symptom Check List 95 (KSCL-95), Insomnia Severity Index (ISI), State-Trait Anxiety Inventory-Korean version (STAI-K), State-Trait Anger Expression Inventory-Korean version (STAXI-K), and the Instrument on Pattern Identifications for Depression and EuroQol-5 Dimension (EQ-5D).
Conclusions: This trial will provide high-quality clinical evidence of the efficacy and safety of BHT in the management of depression.

KCI등재

4The Effect of Alternative Medicine on Quality-of-Life Outcomes for Dementia Patients: A Systematic Review and Meta-Analysis

저자 : So Young Lee , In Chul Jung , Eun Cho

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 401-424 (24 pages)

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Objectives: As effective treatments for dementia are lacking in Western medicine, complementary and alternative medicine (CAM) is considered a useful option. While the quality of life (QoL) is a vital outcome for patients with dementia, the QoL of patients receiving CAM for dementia remains ambiguous. This study aimed to determine the effect of CAM on QoL outcomes in dementia patients.
Methods: A search was performed using the keywords “dementia,” “Alzheimer's,” “cognitive impairment,” “Chinese,” “Korean,” “oriental,” “herbal,” “acupuncture,” and “quality of life”. All quantitative data were synthesized using R version 4.1.1.
Results: Twenty-five randomized controlled trials (RCTs), 16 pre-post trials, and two cohort studies were selected for the systematic review. QoL in Alzheimer's disease (QOL-AD) (n=11, 25.6%) and geriatric QoL in dementia (GQOL-D, n=9, 20.9%) were the most utilized QoL instruments. Significant benefits in QoL were observed after receiving mind, body, combined mind and body, nursing, oriental medicine, and acupuncture therapies. In the meta-analysis, the combined effect was shown to significantly increase QOL-AD compared to before CAM interventions (standardized mean difference, SMD: 0.507; 95% confidence interval (CI), 0.191∼0.824; p<0.01). The overall synthesized estimates in the GQOL-D showed a significantly improved QoL (SMD: 0.537, 95% CI: 0.238∼0.837 p<0.01; one group; SMD: 1.465, 95% CI: 0.934∼1.996, p<0.01). The seven studies assessing the cost-effectiveness of CAM reported uncertain outcomes.
Conclusions: This study showed that CAM interventions benefited patients with dementia by improving their QoL. While additional standardized research is required, CAMs are suggested as effective clinical management for patients with dementia. They are also suggested as complementing therapies for these patients.

KCI등재

5수술 후 환자의 수면 개선에 대한 한의치료 임상연구 동향 -한약, 침, 뜸 치료를 중심으로-

저자 : 조준희 ( Jun-hee Cho ) , 김보경 ( Bo-kyung Kim ) , 임정화 ( Jung-hwa Lim )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 425-451 (27 pages)

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Objectives: To review trends of clinical trials on Korean medicine treatments for postoperative sleep improvement.
Methods: We searched randomized controlled trials (RCTs) on Korean medicine treatments for postoperative sleep improvement from ten domestic and foreign databases. Sample sizes, diseases, types of operation, diagnosis tools, pattern identification, interventions, outcome measurements, and main results of included studies were extracted and analyzed.
Results: A total of 20 RCTs were selected. Most studies were published in China. The most common target disease was cancer, followed by cardiovascular disease. Most studies lacked detailed description regarding participants such as onset, duration of sleep disturbance, and preoperative sleep issues. Herbal medicine was the most frequently used in 12 studies. The most commonly used prescription was Suanzaoren decoction. The effectiveness of Korean medicine treatment on improving postoperative sleep was found to be significant in most studies.
Conclusions: Korean medicine treatments might be effective in postoperative sleep improvement. However, the quality of included studies was low. Therefore, further well-designed research studies are needed to provide high quality clinical evidence on Korean medicine treatments for postoperative sleep improvement.

KCI등재

6한의치료를 통해 인지 장애, 배뇨 장애, 보행 장애에 개선을 보인 뇌의 신생물 및 신생물 주변의 뇌실내출혈을 동반한 뇌내출혈 환자 한방 치험 1례에 대한 증례 보고

저자 : 김상범 ( Sang-beom Kim ) , 이형우 ( Hyung-woo Lee ) , 조주연 ( Ju-yeon Cho ) , 송승우 ( Seung-woo Song ) , 이주현 ( Ju-hyun Lee ) , 박세진 ( Se-jin Park )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 453-462 (10 pages)

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Objectives: The purpose of this clinical case study was to report the effect of Korean medicine treatment on a stroke patient with cognitive impairment, dysuria, and gait disturbance.
Methods: The patient was treated with Korean medicine, including herbal medicine, acupuncture, moxibustion, and cupping. We administered the Korean version of the Mini-Mental Status Examination (MMSE-K) Global Deterioration Scale (GDS) and Manual Muscle Test (MMT) and investigated the frequency of nocturia to evaluate the effectiveness of the treatment and improvement in symptoms.
Results: After Korean medicine treatment, the patient's symptoms were significantly improved. according to the MMSE-K, frequency of nocturia, and MMT results.
Conclusions: This clinical case study suggests that Korean medicine treatment, including Wuchasinkihwan- gagam could be an effective treatment for stroke patients with symptoms of cognitive impairment, dysuria, and gait disturbance.

KCI등재

7배우자 외도로 인한 60대 화병 환자의 M&L 심리치료 프로그램 적용 치험례

저자 : 조주연 ( Ju Yeon Cho ) , 김상범 ( Sang Beom Kim ) , 김다담 ( Da Dam Kim ) , 강형원 ( Hyung Won Kang )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 463-471 (9 pages)

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Objectives: The purpose of this study is to introduce the progress of treatment and improve clinical use after the application of Mindfulness & Loving Beingness psychotherapy, for a patient with Hwa-Byung.
Methods: The patient was diagnosed with Hwa-Byung which arose as a result of their spouse's affair. The patient mainly reported chest pains, breathing difficulties, fear, and anxiety as symptoms. To address these, we administered a combination of M&L psychotherapy and Korean therapy including Herbal medicine, acupuncture, and moxibustion. Beck's Depression Inventory(BDI), Beck's Anxiety Inventory(BAI), and Hwa-Byung scale were evaluated before and after the treatment, to assess the clinical effect.
Results: Following treatment, the patient's overall clinical symptoms of chest pain, breathing discomfort, fear, and anxiety were significantly reduced. Additionally, their scores on the BDI, BAI, and Hwa-Byung scales decreased.
Conclusions: M&L psychotherapy and Korean therapy can be effective in treating Hwa-Byung.

KCI등재

8후각 감퇴 등의 신체적 증상을 동반한 경도 우울에피소드 환자의 실존주의 심리치료를 포함한 한방정신요법 활용 1례 보고

저자 : 이형우 ( Hyung-woo Lee ) , 김상범 ( Sang-beom Kim ) , 조주연 ( Ju-yeon Cho ) , 김종민 ( Jong-min Kim ) , 이가현 ( Ga-hyun Lee ) , 박세진 ( Se-jin Park )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 473-484 (12 pages)

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Objectives: To report a case of a patient with a mild depressive episode accompanied by physical symptoms such as hyposmia visiting a Korean medicine hospital who was treated with oriental psychotherapy in parallel with existentialism-based psychotherapy showing improvement.
Methods: For this patient, Korean medicine Psychotherapy was mainly used for treatment. In parallel, existential Psychotherapy, acupuncture treatment, and self-relaxation training were implemented. For estimating this treatment, changes in results of Beck Depression Index (BDI), Beck Anxiety Index (BAI), Numeric Rating Scale (NRS), Korean Version of Sniffin' Sticks Test (KVSS), Butanol Threshold Test (BTT), Cross-Cultural Smell Identification Test (CC-SIT), and somatic symptoms that the patient subjectively expressed were determined.
Results: After the comprehensive treatment, it was confirmed that changes in BDI, BAI, KVSS, BTT, CC-SIT, NRS, and subjective somatic symptoms expressed by the patient all showed improvements.
Conclusions: We propose that a comprehensive treatment using Korean medicines Psychotherapy in parallel with existential psychotherapy can be used for patients who complain of physical symptoms accompanied by depression and hyposmia.

KCI등재

9대사증후군이 동반된 간화상염 변증 환자에 대한 한의정신요법 병행 한의치료 증례보고

저자 : 조준희 ( Jun-hee Cho ) , 임정화 ( Jung-hwa Lim ) , 김보경 ( Bo-kyung Kim )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 4호 발행 연도 : 2022 페이지 : pp. 485-495 (11 pages)

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The purpose of this study is to report a case of a patient with pattern identification of liver fire flaming upward and metabolic syndrome improved by Korean medicine. The patient felt completely lost. She was treated for headache, insomnia, and metabolic syndrome with Korean medicine and psychotherapy. Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Pattern Identification Tool for Insomnia (PIT-Insomnia), Minnesota multiphasic personality inventory-2 (MMPI-2), and bioelectrical impedance analysis (BIA) were used for assessment. During treatment for six months, the patient stopped taking headache pills. Her blood pressure was stabilized. Her body weight, body fat, body mass index (BMI), and visceral fat decreased significantly. The sum of ISI, PSQI, PIT-insomnia also decreased significantly. Her Ego strength increased in the MMPI-2 supplementary scale. We assume that Korean medicine treatment through acupuncture, herbal medicine, and psychotherapy is effective in treating pattern identification of liver fire flaming upward and metabolic syndrome.

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KCI등재

1오지상승위치료법의 표준매뉴얼 개발을 위한 타당화 연구

저자 : 정문주 ( Moon Joo Cheong ) , 이도은 ( Do-eun Lee ) , 김지수 ( Jeesu Kim ) , 강성현 ( Sunghyun Kang ) , 유영수 ( Yeoung Su Lyu ) , 정인철 ( In Chul Jung ) , 강형원 ( Hyung Won Kang )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 227-239 (13 pages)

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Objectives: The purpose of this study was to develop a standardization manual for Emotion To Emotion therapy. In this study, the processes and categories derived through literature search related to the Emotion To Emotion treatments, were revised and supplemented by the expert FGI (Focus Group Interview). Afterwards, the expert Delphi was conducted, to develop a standard manual for the disease types, purpose, and method of Emotion To Emotion therapy.
Methods: In this study, literature analysis and expert Delphi, as a quantitative research method, were conducted, and the expert Focus Group Interview (FGI) was conducted as a qualitative study. The manual was completed by leading the consensus, on the standardization manual for Emotion To Emotion therapy. After that, a clinical expert Delphi was conducted to test the reliability as well as validity of the manual, through quantitative consensus on the manual of the Emotion To Emotion therapy.
Results: First, as a result of literature studies, to date, studies related to Emotion To Emotion therapy have been qualitatively and quantitatively limited, as comparative literature related to clinical cases. Second, through expert FGI, the manual was structured with eight sub-factors for the indication diagnosis, six sub-factors for the implementation method, and 13 detailed factors. Third, through an expert Delphi, the consensus did the factor of indication, implementation methods, and implementation process, and developed a standardization manual for Emotion To Emotion therapy ver 1.0.
Conclusions: Through literature analysis, expert FGI, and expert Delphi, the Emotion To Emotion therapy standardization manual ver 1.0 was completed, and will proceed with the revision and improvement report.

KCI등재

2핵심칠정척도 단축형을 활용한 건강한 성인의 정서적 특성 및 핵심칠정척도 단축형과 스트레스 한국판 자가척도와의 상관관계

저자 : 임미홍 ( Mi Hong Yim ) , 박정환 ( Jeong Hwan Park ) , 이상훈 ( Sanghun Lee )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 241-257 (17 pages)

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Objectives: To investigate emotional characteristics of healthy adults using the Core Seven Emotions Inventory-Short Form (CSEI-s) and to investigate the correlation between the CSEI-s and Korean version of the Perceived Stress Scale (K-PSS).
Methods: Overall, 2,178 healthy adults aged ≥19 years who completed the CSEI-s and K-PSS in a nationwide multicenter study were included in this study. One-way analysis of variance was performed to identify associations of seven emotions with sociodemographic characteristics. Bonferroni corrected post-hoc tests were performed for multiple comparisons. Pearson's correlation analyses were conducted to examine the correlation between each emotion and stress.
Results: Scores of all emotions except for joy (喜) and stress were significantly greater in women than in men. However, the score of joy (喜) in women was significantly less than that in men. There were significant differences in joy (喜), thought (思), depression (憂), fear (恐), and fright (驚) according to age groups in both men and women. The score of depression (憂) was significantly lower in women attending or graduating from graduate school than in those attending or graduating from undergraduate school. Significantly lower scores in joy (喜), thought (思), depression (憂), sorrow (悲), fear (恐), and fright (驚) were observed in married men than in single men. There were significant positive correlations between depression (憂) and stress and between sorrow (悲) and stress in both men and women.
Conclusions: There were significant associations of seven emotions with sociodemographic characteristics in healthy adults.

KCI등재

3클로닌저의 생리심리사회 모델에서 위험회피-자율성 프로파일에 따른 다면적 정신건강 특성

저자 : 채한 ( Han Chae ) , 이수진 ( Soo Jin Lee )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 259-266 (8 pages)

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Objectives: The combination of Harm-Avoidance (HA) and Self-Directedness (SD) of Temperament and Character Inventory (TCI) has been reported pivotal for mental health; however its clinical usefulness in integrative medicine has not sufficiently reported. The purpose of this study was to illustrate multi- phasic mental health of subjective satisfaction with life, emotional well-being, and psychopathology, following the HA-SD profile groups.
Methods: A total of 527 Korean university students reported HA and SD scores as to render their HA-SD profile, and multi-phasic mental health characteristics using Satisfaction with Life Scale (SWLS), Positive Affect and Negative Affect Schedule (PANAS), and Beck Depression Inventory (BDI) with composite well-being scales of SC (Sum of Self-Directedness and Cooperativeness score) and HI (Happiness Index, subtraction of Negative Affect (NA) score from Positive Affect (PA) score) as standardized. Pearson's correlation was used to report correlation coefficient, and the ANCOVA with age and sex as covariates, to show significant differences in mental health and well-being between the HA-SD profile groups.
Results: The HA-SD profile groups showed distinctive multi-phasic mental health characteristics; health related scores of SWLS, PA, SC and HI decreased following the order of hS (low HA and high SD), HS (high HA and high SD), hs (low HA and low SD) and Hs (high HA and low SD) profile groups; however the non-health related scores of NA and BDI showed contrasting order.
Conclusions: The HA-SD profile was found to be clinically useful for examining multi-phasic mental health and well-being status, and the TCI may be an imperative personality inventory for integrative medicine.

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4현직 한의사의 열등감 경험에 대한 내러티브 탐구: 질적연구

저자 : 배진수 ( Jin-soo Bae ) , 김경옥 ( Kyeong-ok Kim )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 267-276 (10 pages)

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Objectives: The purpose of this study was to explore the vivid and in-depth stories, of inferiority experienced in the lives of current Korean medicine doctors.
Methods: In-depth interviews were conducted, with two participants. Collected research data were analyzed, using the narrative inquiry method suggested by Clandinin and Connelly.
Results: Common themes found in participants' narrative were summarized, by 'comparison with others' and 'various attempts to overcome inferiority feeling'.
Conclusions: This study is meaningful at three levels: personal, social, and practical. Also, it provides readers with an opportunity to reflect on the way they cope with their inferiority complex, which various people experience in different contexts.

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5LPS에 의해 유도된 인지기능 손상모델에 대한 천마 추출물의 방어효과

저자 : 권강범 ( Kang-beom Kwon ) , 김하림 ( Ha-rim Kim ) , 김예슬 ( Ye-seul Kim ) , 박은희 ( Eun-hee Park ) , 강형원 ( Hyung-won Kang ) , 류도곤 ( Do-gon Ryu )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 277-285 (9 pages)

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Objectives: Gastrodia elata (GE) has been used to treat cognition impairment, including Alzheimer's disease (AD) in Korea. The purpose of this study was to investigate the effects of GE water extracts (GEE) on the lipopolysaccharide (LPS)-induced AD model in mice. (Aβ).
Methods: We classified six groups as follow; group 1: control (CON), group 2: LPS (0.5 mg/kg/day, four times), group 3: 4 mg/kg donepezil (DP), group 4: 100 mg/kg GEE+LPS, group 5: 200 mg/kg GEE+LPS, group 6: 500 mg/kg GEE+LPS.
Results: We found that GEE has an effect that inhibits decrease of discrimination index in object recognition test, as well as spontaneous alteration in the Y-maze test by LPS. Treatment with LPS increased amlyloid-β (Aβ) concentration, and decreased brain-derived neurotrophic factor (BDNF) in cerebral cortex of mice. However, GEE significantly protected against LPS-induced Aβ and BDNF changes. Our findings also showed that the inflammatory cytokines 〔tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β)〕 mRNA and protein were up-regulated by the LPS injection. But GEE significantly suppressed LPS-induced inflammatory cytokines increase in a dose-dependent manner.
Conclusions: This study suggests that the GEE may be an effective AD therapeutic agent, in treating neurodegenerative diseases including AD.

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6불면증 관련 천연물 추출물의 특허 동향 분석

저자 : 이정경 ( Jung-gyung Lee ) , 강성현 ( Sung-hyun Kang ) , 권찬영 ( Chan-young Kwon )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 287-299 (13 pages)

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Objectives: The purpose of this study was to analyze the trend of natural product-based products for sleep improvement in Korean patents, to enhance the development and application of natural-products for sleep disorder in terms of Korean medicine.
Methods: We collected patent data using the KIPRIS database and ScienceON database. Two authors independently screened patents that potentially met the criteria, and assessed full texts of screened patents for eligibility. Included patents were analyzed, quantitatively as well as qualitatively.
Results: A total of 60 patents were selected 2008-July 2022. The number of patents have been on the rise since 2017, and reached 12 in 2018. Companies have registered the most patents, followed by the Industry-University Cooperation Foundation. Zizyphi semen (n=6), Lactuca sativa L. (n=5), Valeriana fauriei/officinalis (n=4), Poria cocos (n=4) were frequently used herbs among 60 patents. Twenty-one patents (35%) included medicinal herbs with sleep improving effects. Among 60 patents, alcohol extraction (70%) was mostly used, followed by water immersion (50%), and hot water extraction (48.3%).
Conclusions: Analysis results showed that various Korean medicine herbs, are being used for natural-products for sleep disorder. The results will be helpful towards inventing new patents using Korean medicine, developing natural product extracts for sleep improvement, and extending the range of these products in clinical use.

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7불안에 대한 한의정신요법과 중의정신요법의 비교고찰: 임상연구를 중심으로

저자 : 이지원 ( Ji-won Lee ) , 황인준 ( In-jun Hwang ) , 박민령 ( Min-ryeong Park ) , 권찬영 ( Chan-young Kwon )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 301-316 (16 pages)

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Objectives: To compare Korean medicine (KM) and traditional Chinese medicine (TCM) psychotherapy for anxiety.
Methods: Databases including MEDLINE (via PubMed), EMBASE (via Elsevier), Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, and Oriental Medicine Advanced Searching Integrated System were comprehensively searched. Prospective clinical studies on KM or TCM psychotherapy for patients with anxiety disorder or individuals with elevated anxiety levels published up to August 3, 2022 were reviewed. Psychotherapy was divided into counselling, art therapy, and meditation according to its characteristics.
Results: A total of 12 clinical studies were reviewed, including nine randomized controlled trials. The most common disorder investigated was post-traumatic stress disorder. Ten studies used TCM psychotherapy and two used KM psychotherapy. As for differences between TCM psychotherapy and KM psychotherapy, TCM psychotherapy utilized pattern identification in the procedure more actively than KM psychotherapy. In addition, some TCM studies have attempted to directly converge Western psychotherapy (i.e., hypnosis) and Eastern psychotherapy (i.e., Taoin qigong therapy). In the case of KM psychotherapy, there was an attempt to incorporate psychotherapy with Sasang constitutional medicine. Reported effects of TCM psychotherapy and KM psychotherapy on anxiety were positive.
Conclusions: Research status of KM psychotherapy and TCM psychotherapy for anxiety was investigated, revealing some of their characteristics, commonalities, and differences. Findings of this review have the potential to provide a clue to the development of conventional KM psychotherapy and new medical technology for KM psychotherapy.

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8우울, 불안 척도를 통해 살펴본 우울증 환자에 대한 한의학적 치료 효과에 대한 연구

저자 : 안윤영 ( Yunyoung An ) , 김락형 ( Lakhyung Kim ) , 유종호 ( Jongho Yoo )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 317-327 (11 pages)

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Objectives: To examine clinical effects of Korean medical treatment on depressive disorder.
Methods: Medical records of 102 patients diagnosed with depressive disorder who were treated with Korean medical treatment (herbal-medication, acupuncture, Korean psychotherapy) for at least 12 weeks and measured psychological scales (Beck Depression Inventory-II (BDI-II), State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and State-Trait Anger Expression Inventory (STAXI)) every 4 weeks were analyzed.
Results: After 12 weeks of treatment, BDI-II, STAI-X-1/2, BAI, and STAXI-S/T all decreased statistically significantly. STAI-X-1 and BAI were significantly decreased throughout the treatment interval (comparisons every 4 weeks). The other four scales decreased significantly from 0 to 4 weeks and from 8 to 12 weeks.
Conclusions: Treatment for depressive disorder with Korean Medicine was effective not only in improving overall symptoms of depressed patients, but also in improving accompanying anxiety, anger, and physical symptoms. In addition, since all scores were gradually decreased, continuous treatment would be important.

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9강박장애 환자의 한방치료 효과에 대한 후향적 연구

저자 : 최강의 ( Kang-eah Choi ) , 이유진 ( Yu-jin Lee ) , 김연주 ( Yeonju Kim ) , 유종호 ( Jong-ho Yoo )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 329-337 (9 pages)

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Objectives: To examine effects of traditional Korean medical treatment on obsessive-compulsive disorder (OCD).
Methods: Effects of Korean medical treatment on patients with OCD who visited the neuropsychiatric clinic of Korean medicine were examined. Patients were treated with acupuncture, herbal medication, and oriental psychotherapy. Padua-ICMA, Y-BOCS, BDI-2, STAI-X1/X2, BAI were compared before and after 8 and 12 weeks of treatment to determine whether symptoms of patients were improved.
Results: After 8 weeks treatment (n=19), Padua-ICMA, Y-BOCS, BDI-2, STAI-X1/X2, and BAI scores were significantly decreased. After 12 weeks treatment (n=12), Padua-ICMA, Y-BOCS, BDI-2, STAI-X1/X2, and BAI scores were also significantly decreased.
Conclusions: Traditional Korean medicine is clinically effective in treating OCD.

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10수술 후 섬망 치험 1례를 통해 본 지언고론요법의 활용

저자 : 강동훈 ( Dong Hoon Kang ) , 김주연 ( Ju Yeon Kim ) , 정인철 ( In Chul Jung )

발행기관 : 대한한방신경정신과학회 간행물 : 동의신경정신과학회지 33권 3호 발행 연도 : 2022 페이지 : pp. 339-349 (11 pages)

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Objectives: The purpose of this study was to report the effectiveness of the combination of Giungoroen-therapy, as well as other Korean medicine therapy on postoperative delirium.
Methods: The patient was diagnosed with postoperative delirium, that occurred after arthroscopic debridement two months before hospitalization. The patient received Giungoroen-therapy in addition to conventional Korean Medicine treatment, including acupuncture, herbal medicine, and moxibustion. The evaluation variables to check the effectiveness of the interventions, were the Korean Nursing Delirium Screening Scale (Korean Nu-DESC) and the Korean Version of the Delirium Rating Scale-Revised-98 (K-DRS-R-98).
Results: During the hospitalization period, the Korean Nu-DESC score decreased from 5 to 1, and the K-DRS-R-98 score decreased from 36 to 23. The subjective expression of anxiety had been reduced.
Conclusions: The combination of Giungoroen-therapy, as well as other Korean medicine therapy including acupuncture, moxibustion, and herbal medicine may be useful in alleviating postoperative delirium.

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