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대한소화기내시경학회> Clinical Endoscopy> Fecal Calprotectin as a Surrogate Marker for Mucosal Healing After Initiating the Therapeutic Anti-Tubercular Trial

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Fecal Calprotectin as a Surrogate Marker for Mucosal Healing After Initiating the Therapeutic Anti-Tubercular Trial

Satimai Aniwan
  • : 대한소화기내시경학회
  • : Clinical Endoscopy 55권2호
  • : 연속간행물
  • : 2022년 03월
  • : 210-212(3pages)
Clinical Endoscopy

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UCI(KEPA)

간행물정보

  • : 의약학분야  > 내과학
  • : KCI등재
  • : SCOPUS
  • : 격월
  • : 2234-2400
  • : 2234-2443
  • : 학술지
  • : 연속간행물
  • : 2011-2022
  • : 1270


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1Quality indicators in esophagogastroduodenoscopy

저자 : Sang Yoon Kim , Jae Myung Park

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 319-331 (13 pages)

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Esophagogastroduodenoscopy (EGD) has been used to diagnose a wide variety of upper gastrointestinal diseases. In particular, EGD is used to screen high-risk subjects of gastric cancer. Quality control of EGD is important because the diagnostic rate is examiner-dependent. However, there is still no representative quality indicator that can be uniformly applied in EGD. There has been growing awareness of the importance of quality control in improving EGD performance. Therefore, we aimed to review the available and emerging quality indicators for diagnostic EGD.

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2Quality indicators in colonoscopy: the chasm between ideal and reality

저자 : Su Bee Park , Jae Myung Cha

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 332-338 (7 pages)

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Continuous measurement of quality indicators (QIs) should be a routine part of colonoscopy, as a wide variation still exists in the performance and quality levels of colonoscopy in Korea. Among the many QIs of colonoscopy, the adenoma detection rate, average withdrawal time, bowel preparation adequacy, and cecal intubation rate should be monitored in daily clinical practice to improve the quality of the procedure. The adenoma detection rate is the best indicator of the quality of colonoscopy; however, it has many limitations for universal use in daily practice. With the development of natural language processing, the adenoma detection rate is expected to become more effective and useful. It is important that colonoscopists do not strictly and mechanically maintain an average withdrawal time of 6 minutes but instead perform careful colonoscopy to maximally expose the colonic mucosa with a withdrawal time of at least 6 minutes. To achieve adequate bowel preparation, documentation of bowel preparation with the Boston Bowel Preparation Scale (BBPS) should be a routine part of colonoscopy. When colonoscopists routinely followed the bowel preparation protocols, ≥85% of outpatient screening colonoscopies had a BBPS score of ≥6. In addition, the cecal intubation rate should be ≥95% of all screening colonoscopies. The first step in improving colonoscopy quality in Korea is to apply these key performance measurements in clinical practice.

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3Endoscopic clipping in non-variceal upper gastrointestinal bleeding treatment

저자 : Giuseppe Galloro , Angelo Zullo , Gaetano Luglio , Alessia Chini , Donato Alessandro Telesca , Rosa Maione , Matteo Pollastro , Giovanni Domenico De Palma , Raffaele Manta

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 339-346 (8 pages)

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Since the earliest reports, advanced clipping systems have been developed, and it is possible to choose among many models with different structural and technical features. The main drawback of through-the-scope clips is their small size, which allows the compression of limited amounts of tissue needed for large-size vessel treatment. Therefore, the over-the-scope clip system was realized, allowing a larger and stronger mechanical compression of large tissue areas, with excellent results in achieving a definitive hemostasis in difficult cases. Many studies have analyzed the indications and efficacy of two-pronged endoclips and have shown good results for initial and permanent hemostasis. The aim of this review was to provide updated information on indications, positioning techniques, and results of clip application for endoscopic treatment of upper gastrointestinal non-variceal bleeding lesions.

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4Comparing palliative treatment options for cholangiocarcinoma: photodynamic therapy vs. radiofrequency ablation

저자 : Tayyaba Mohammad , Michel Kahaleh

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 347-354 (8 pages)

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Referral to an endoscopist is often done once curative resection is no longer an option for cholangiocarcinoma management. In such cases, palliation has become the main objective of the treatment. Photodynamic therapy and radiofrequency ablation can be performed to achieve palliation, with both procedures associated with improved stent patency and survival. Despite the greatly increased cost and association with photosensitivity, photodynamic therapy allows transmission to the entire biliary tree. In contrast, radiofrequency ablation is cheaper and faster to apply, but requires intraductal contact. This paper reviews both modalities and compares their efficacy and safety for bile duct cancer palliation.

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5Does computer-aided diagnostic endoscopy improve the detection of commonly missed polyps? A meta-analysis

저자 : Arun Sivananthan , Scarlet Nazarian , Lakshmana Ayaru , Kinesh Patel , Hutan Ashrafian , Ara Darzi , Nisha Patel

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 355-364 (10 pages)

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Background/Aims: Colonoscopy is the gold standard diagnostic method for colorectal neoplasia, allowing detection and resection of adenomatous polyps; however, significant proportions of adenomas are missed. Computer-aided detection (CADe) systems in endoscopy are currently available to help identify lesions. Diminutive (≤5 mm) and nonpedunculated polyps are most commonly missed. This meta-analysis aimed to assess whether CADe systems can improve the real-time detection of these commonly missed lesions.
Methods: A comprehensive literature search was performed. Randomized controlled trials evaluating CADe systems categorized by morphology and lesion size were included. The mean number of polyps and adenomas per patient was derived. Independent proportions and their differences were calculated using DerSimonian and Laird random-effects modeling.
Results: Seven studies, including 2,595 CADe-assisted colonoscopies and 2,622 conventional colonoscopies, were analyzed. CADe-assisted colonoscopy demonstrated an 80% increase in the mean number of diminutive adenomas detected per patient compared with conventional colonoscopy (0.31 vs. 0.17; effect size, 0.13; 95% confidence interval [CI], 0.09-0.18); it also demonstrated a 91.7% increase in the mean number of nonpedunculated adenomas detected per patient (0.32 vs. 0.19; effect size, 0.05; 95% CI, 0.02-0.07).
Conclusions: CADe-assisted endoscopy significantly improved the detection of most commonly missed adenomas. Although this method is a potentially exciting technology, limitations still apply to current data, prompting the need for further real-time studies.

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6Lessons learned in clinical epidemiology of esophageal adenocarcinoma

저자 : Hye Kyung Jung

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 365-366 (2 pages)

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7A new band ligation device to treat colonic diverticular bleeding

저자 : Yunho Jung

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 367-368 (2 pages)

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8Covered self-expandable metal stents for distal biliary obstruction from pancreatic carcinoma: what type of stent is preferred?

저자 : Hideyuki Shiomi , Ryota Nakano , Shogo Ota

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 369-371 (3 pages)

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9Epidemiology of early esophageal adenocarcinoma

저자 : Thuy-van P. Hang , Zachary Spiritos , Anthony M. Gamboa , Zhengjia Chen , Seth Force , Vaishali Patel , Saurabh Chawla , Steven Keilin , Nabil F. Saba , Bassel El-rayes , Qiang Cai , Field F. Willingham

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 372-380 (9 pages)

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Background/Aims: Endoscopic resection has become the preferred treatment approach for select early esophageal adenocarcinoma (EAC); however, the epidemiology of early stage disease has not been well defined.
Methods: Surveillance Epidemiology and End Results (SEER) data were analyzed to determine age-adjusted incidence rates among major epithelial carcinomas, including EAC, from 1973 to 2017. The percent change in incidence over time was compared according to tumor subtype. Early T-stage, node-negative EAC without metastasis was examined from 2004 to 2017 when precise T-stage data were available.
Results: The percent change in annual incidence from 1973 to 2017 was 767% for EAC. Joinpoint analysis showed that the average annual percent change in EAC from 1973 to 2017 was 5.11% (95% confidence interval, 4.66%-5.56%). The annual percent change appeared to plateau between 2004 and 2017; however, early EAC decreased from 2010 to 2017, with an annual percent change of -5.78%.
Conclusions: There has been a 7-fold increase in the incidence of EAC, which was significantly greater than that of the other major epithelial malignancies examined. More recently, the incidence of early EAC has been decreasing. Approximately one in five patients has node negative, potentially resectable early stage disease.

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10Outcomes of endoscopic submucosal dissection for superficial esophageal neoplasms in patients with liver cirrhosis

저자 : Young Kwon Choi , Jin Hee Noh , Do Hoon Kim , Hee Kyong Na , Ji Yong Ahn , Jeong Hoon Lee , Kee Wook Jung , Kee Don Choi , Ho June Song , Gin Hyug Lee , Hwoon-yong Jung

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 3호 발행 연도 : 2022 페이지 : pp. 381-389 (9 pages)

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Background/Aims: The treatment of superficial esophageal neoplasms (SENs) in cirrhotic patients is challenging and rarely investigated. We evaluated the outcomes of endoscopic submucosal dissection (ESD) to determine the efficacy and safety of treating SENs in patients with liver cirrhosis.
Methods: The baseline characteristics and treatment outcomes of patients who underwent ESD for SENs between November 2005 and December 2017 were retrospectively reviewed.
Results: ESD was performed in 437 patients with 481 SENs, including 15 cirrhotic patients with 17 SENs. En bloc resection (88.2% vs. 97.0%) and curative resection (64.7% vs. 78.9%) rates were not different between the cirrhosis and non-cirrhosis groups (p=0.105 and p=0.224, respectively). Bleeding was more common in cirrhotic patients (p=0.054), and all cases were successfully controlled endoscopically. The median procedure and hospitalization duration did not differ between the groups. Overall survival was lower in cirrhotic patients (p=0.003), while disease-specific survival did not differ between the groups (p=0.85).
Conclusions: ESD could be a safe and effective treatment option for SENs in patients with cirrhosis. Detailed preprocedural assessments are needed, including determination of liver function, esophageal varix status, and remaining life expectancy, to identify patients who will obtain the greatest benefit.

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12021 Korean Society of Gastrointestinal Endoscopy Clinical Practice Guidelines for Endoscopic Sedation

저자 : Hong Jun Park , Byung-wook Kim , Jun Kyu Lee , Yehyun Park , Jin Myung Park , Jun Yong Bae , Seung Young Seo , Jae Min Lee , Jee Hyun Lee , Hyung Ku Chon , Jun-won Chung , Hyun Ho Choi , Myung Ha Kim ,

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 167-182 (16 pages)

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Sedation can resolve anxiety and fear in patients undergoing endoscopy. The use of sedatives has increased in Korea. Appropriate sedation is a state in which the patient feels subjectively comfortable while maintaining the airway reflex for stable spontaneous breathing. The patient should maintain a state of consciousness to the extent that he or she can cooperate with the needs of the medical staff. Despite its benefits, endoscopic sedation has been associated with cardiopulmonary complications. Cardiopulmonary complications are usually temporary. Most patients recover without sequelae. However, they may progress to serious complications, such as cardiovascular collapse. Therefore, it is essential to screen high-risk patients before sedation and reduce complications by meticulous monitoring. Additionally, physicians should be familiar with the management of emergencies. The first Korean clinical practice guideline for endoscopic sedation was developed based on previous worldwide guidelines for endoscopic sedation using an adaptation process. The guideline consists of nine recommendations based on a critical review of currently available data and expert consensus when the guideline was drafted. These guidelines should provide clinicians, nurses, medical school students, and policy makers with information on how to perform endoscopic sedation with minimal risk. Clin Endosc 2022;55:167-182

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2Can Computed Tomography Colonography Replace Optical Colonoscopy in Detecting Colorectal Lesions?: State of the Art

저자 : Alessia Chini , Michele Manigrasso , Grazia Cantore , Rosa Maione , Marco Milone , Francesco Maione , Giovanni Domenico De Palma

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 183-190 (8 pages)

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Colorectal cancer is an important cause of morbidity and mortality worldwide. Optical colonoscopy (OC) is widely accepted as the reference standard for the screening of colorectal polyps and cancers, and computed tomography colonography (CTC) is a valid alternative to OC. The purpose of this review was to assess the diagnostic accuracy of OC and CTC for colorectal lesions. A literature search was performed in PubMed, Embase, and Cochrane Library, and 18 articles were included. CTC has emerged in recent years as a potential screening examination with high accuracy for the detection of colorectal lesions. However, the clinical application of CTC as a screening technique is limited because it is highly dependent on the size of the lesions and has poor performance in detecting individual lesions <5 mm or flat lesions, which, although rarely, can have a malignant potential. Clin Endosc 2022;55:183-190

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3Single Use (Disposable) Duodenoscope: Recent Development and Future

저자 : Kihyun Ryu , Sunguk Jang

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 191-196 (6 pages)

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Unlike simple forward-viewing endoscopes such as gastroscope or colonoscope, duodenoscope houses much more complex design to fulfil its function. This design differences leave duodenoscopes more prone to contamination from inadequate disinfection process and potential dissemination of pathogens. Recent reports on dissemination of infection through the duodenoscope mandated an overhaul of duodenoscope utilization including development of a disposable duodenoscope. This article reviews the current state of disposable duodenoscope development, including reported early efficacy as well as its future direction and utilization. Clin Endosc 2022;55:191-196

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4Confocal Laser Endomicroscopy in the Diagnosis of Biliary and Pancreatic Disorders: A Systematic Analysis

저자 : Do Han Kim , Somashekar G. Krishna , Emmanuel Coronel , Paul T. Kröner , Herbert C. Wolfsen , Michael B. Wallace , Juan E. Corral

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 197-207 (11 pages)

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Background/Aims: Endoscopic visualization of the microscopic anatomy can facilitate the real-time diagnosis of pancreatobiliary disorders and provide guidance for treatment. This study aimed to review the technique, image classification, and diagnostic performance of confocal laser endomicroscopy (CLE).
Methods: We conducted a systematic review of CLE in pancreatic and biliary ducts of humans, and have provided a narrative of the technique, image classification, diagnostic performance, ongoing research, and limitations.
Results: Probe-based CLE differentiates malignant from benign biliary strictures (sensitivity, ≥89%; specificity, ≥61%). Needle-based CLE differentiates mucinous from non-mucinous pancreatic cysts (sensitivity, 59%; specificity, ≥94%) and identifies dysplasia. Pancreatitis may develop in 2-7% of pancreatic cyst cases. Needle-based CLE has potential applications in adenocarcinoma, neuroendocrine tumors, and pancreatitis (chronic or autoimmune). Costs, catheter lifespan, endoscopist training, and interobserver variability are challenges for routine utilization.
Conclusions: CLE reveals microscopic pancreatobiliary system anatomy with adequate specificity and sensitivity. Reducing costs and simplifying image interpretation will promote utilization by advanced endoscopists. Clin Endosc 2022;55:197-207

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5A Novel Aerosol-Exposure Protection Mask for Patients During Upper Endoscopy

저자 : Soo-jeong Cho

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 208-209 (2 pages)

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6Fecal Calprotectin as a Surrogate Marker for Mucosal Healing After Initiating the Therapeutic Anti-Tubercular Trial

저자 : Satimai Aniwan

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 210-212 (3 pages)

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7Predicting Malignancy by Peroral Pancreatoscopy of an Intraductal Papillary Mucinous Neoplasm with a Dilated Main Pancreatic Duct: Is Seeing Enough?

저자 : Yun Nah Lee , Jong Ho Moon

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 213-214 (2 pages)

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8Perception of Gastrointestinal Endoscopy Personnel on Society Recommendations on Personal Protective Equipment, Case Selection, and Scope Cleaning During Covid-19 Pandemic: An International Survey Study

저자 : Parit Mekaroonkamol , Kasenee Tiankanon , Rapat Pittayanon , Wiriyaporn Ridtitid , Fariha Shams , Ghias Un Nabi Tayyab , Julia Massaad , Saurabh Chawla , Stanley Khoo , Siriboon Attasaranya , Nonthalee Pausawasdi

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 215-225 (11 pages)

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Background/Aims: The Thai Association for Gastrointestinal Endoscopy published recommendations on safe endoscopy during the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to assess the practicality and applicability of the recommendations and the perceptions of endoscopy personnel on them.
Methods: A validated questionnaire was sent to 1290 endoscopy personnel globally. Of these, the data of all 330 responders (25.6%) from 15 countries, related to the current recommendations on proper personal protective equipment (PPE), case selection, scope cleaning, and safety perception, were analyzed. Ordinal logistic regression was used to determine the relationships between the variables.
Results: Despite an overwhelming agreement with the recommendations on PPE (94.5%) and case selection (95.5%), their practicality and applicability on PPE recommendations and case selection were significantly lower (p=0.001, p=0.047, p<0.001, and p=0.032, respectively). Factors that were associated with lower sense of safety in endoscopy units were younger age (p=0.004), less working experience (p=0.008), in-training status (p=0.04), and higher national prevalence of COVID-19 (p=0.003). High prevalent countries also had more difficulty implementing the guidelines (p<0.001) and they considered the PPE recommendations less practical and showed lower agreement with them (p<0.001 and p=0.008, respectively). A higher number of in-hospital COVID-19 patients was associated with less agreement with PPE recommendations (p=0.039).
Conclusions: Using appropriate PPE and case selection in endoscopic practice during a pandemic remains a challenge. Resource availability and local prevalence are critical factors influencing the adoption of the current guidelines. Clin Endosc 2022;55:215-225

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9Preclinical Efficacy and Clinical Feasibility of a Novel Aerosol-Exposure Protection Mask for Esophagogastroduodenoscopy

저자 : Mai Ego Makiguchi , Seiichiro Abe , Yutaka Okagawa , Satoru Nonaka , Haruhisa Suzuki , Shigetaka Yoshinaga , Ichiro Oda , Okamoto Ryuta , Yutaka Saito

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 226-233 (8 pages)

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Background/Aims: This study aimed to assess the efficacy of a novel aerosol-exposure protection (AP) mask in preventing coronavirus disease in healthcare professionals during upper gastrointestinal endoscopy and to evaluate its clinical feasibility.
Methods: In Study 1, three healthy volunteers volitionally coughed with and without the AP mask in a cleanroom. Microparticles were visualized and counted with a specific measurement system and compared with and without the AP mask. In Study 2, 30 patients underwent endoscopic resection with the AP mask covering the face, and the SpO2 was measured throughout the procedure.
Results: In Study 1, the median number of microparticles in volunteers 1, 2, and 3 with and without the AP mask was 8.5 and 110.0, 7.0 and 51.5, and 8.0 and 95.0, respectively (p<0.01). Using the AP mask, microparticles were reduced by approximately 92%. The median distances of microparticle scattering without the AP mask were 60, 0, and 68 in volunteers 1, 2, and 3, respectively. In Study 2, the mean SpO2 was 96.3%, and desaturation occurred in three patients.
Conclusion: The AP mask could provide protection from aerosol exposure and can be safely used for endoscopy in clinical practice. Clin Endosc 2022;55:226-233

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10Propofol Alone versus Propofol in Combination with Midazolam for Sedative Endoscopy in Patients with Paradoxical Reactions to Midazolam

저자 : Ji Hyung Nam , Dong Kee Jang , Jun Kyu Lee , Hyoun Woo Kang , Byung-wook Kim , Byung Ik Jang

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 55권 2호 발행 연도 : 2022 페이지 : pp. 234-239 (6 pages)

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Background/Aims: The efficacy of propofol in gastrointestinal endoscopy for patients with midazolam-induced paradoxical reactions remains unclarified. This study aimed to compare the efficacy and safety of propofol-based sedation in patients who previously experienced paradoxical reactions.
Methods: This was a prospective, single-blinded, randomized controlled pilot study. Participants with a history of paradoxical reactions to midazolam during a previous esophagogastroduodenoscopy were recruited and randomly assigned to group I (propofol monosedation) or group II (combination of propofol and midazolam). The primary endpoint was the occurrence of a paradoxical reaction.
Results: A total of 30 participants (mean age, 54.7±12.6 years; male, 19/30) were randomly assigned to group I (n=16) or group II (n=14). There were no paradoxical reactions in group I, but there were two in group II, without a significant difference (p=0.209). The mean dose of propofol was higher in group I than in group II (p=0.002). Meanwhile, the procedure and recovery times did not differ between groups.
Conclusions: Propofol-based sedation was safe and effective for patients who experienced paradoxical reactions to midazolam. However, caution is needed because few cases of paradoxical reaction again can happen in group II in which midazolam was readministered. Clin Endosc 2022;55:234-239

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