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대한피부과학회> 대한피부과학회지> 악성 흑색종에 대한 한국어 유튜브 동영상의 질 평가

KCI등재SCOUPUS

악성 흑색종에 대한 한국어 유튜브 동영상의 질 평가

Quality Evaluation of Korean YouTube Videos as a Source of Information on Malignant Melanoma

허근영 ( Keunyoung Hur ) , 하은서 ( Eun-seo Ha ) , 김동효 ( Dong Hyo Kim ) , 송원지 ( Won Ji Song ) , 문제호 ( Je-ho Mun )
  • : 대한피부과학회
  • : 대한피부과학회지 60권3호
  • : 연속간행물
  • : 2022년 03월
  • : 143-150(8pages)
대한피부과학회지

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Background: Disseminating public knowledge on malignant melanoma through YouTube is an important way to bridge the gap between physicians and patients. However, videos recorded on this topic in Korea are yet to be evaluated.
Objective: We aimed to evaluate the quality of YouTube videos on malignant melanoma recorded in Korea. We also investigated whether there was a difference in the quality of videos made by medical professionals (subdivided into dermatologists and non-dermatologists) and non-medical personnel.
Methods: We included all videos recorded in Korean by searching YouTube using the keywords “melanoma” or “malignant melanoma”. The search was performed on March 22, 2021. The inclusion criterion was videos in Korean language that contained medical information about malignant melanoma. The characteristics and content information were collected for each video. Video quality (DISCERN, Global Quality Scale [GQS], Journal of the American Medical Association [JAMA] benchmark criteria) was analyzed.
Results: Eighty-five videos met the inclusion criterion for the analysis. Fifty-six (66%) and 29 videos (34%) were made by medical and non-medical personnel, respectively. The videos made by medical professionals significantly contained more of the following information than those made by non-medical personnel: clinical information (p<0.001), symptoms and signs (p=0.001), risk factors (p<0.05), diagnosis (p<0.001). Videos made by medical professionals, videos with a length of more than 5 minutes, or videos with more than 10,000 views had significantly higher quality scores (DISCERN, GQS, JAMA).
Conclusion: Considering that YouTube is being used as a portal for medical information, the participation of medical professionals is essential for providing more accurate information. (Korean J Dermatol 2022;60(3):143∼150)

UCI(KEPA)

간행물정보

  • : 의약학분야  > 피부과학
  • : KCI등재
  • : SCOPUS
  • : 월간
  • : 0494-4739
  • : 2713-7627
  • : 학술지
  • : 연속간행물
  • : 1960-2022
  • : 9674


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60권4호(2022년 05월) 수록논문
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KCI등재 SCOPUS

1한국인 50세 이상 여성의 안면 피부 노화와 생활습관 간의 상관관계

저자 : 김승미 ( Seung-mee Kim ) , 이영윤 ( Young Yoon Lee ) , 황초롱 ( Cho-long Hwang ) , 신정민 ( Jung-min Shin ) , 권인선 ( In-sun Kwon ) , 박상현 ( Sang-hyun Park ) , 정경은 ( Kyung Eun Jung ) , 김창덕 ( Chang-deok Kim ) , 서영준 ( Young-joon Seo ) , 홍동균 ( Dongkyun Hong ) , 이영 ( Young L

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 201-208 (8 pages)

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Background: Skin aging can be divided into intrinsic and extrinsic processes, and occur due to several factors. Although the interest in skin youthfulness is increasing globally, research on facial skin youthfulness and lifestyle is limited.
Objective: This study aimed to evaluate the association between facial skin youthfulness and biophysical facial skin parameters in Korean women over 50 years of age. We further investigated lifestyle factors that make people appear younger than their chronological age.
Methods: We surveyed the essential information and lifestyle of subjects by questionnaires, and measured the biophysical parameters of the facial skin. We then performed clinical facial assessments, and the values were compared with the chronologic age. The associations between age differences, biophysical parameters, and living habits were evaluated.
Results: We identified a positive correlation between age and melanin index (r=0.245, p<0.001) and erythema index (r=0.119, p=0.002). The melanin index was statistically significantly lower in the group without regular outdoor activities (144.66±43.24 vs. 137.00±55.48, p=0.043). The melanin index and erythema index were the significant differences that defined younger perceived age than chronological age. The perceived age was younger in the group who wore a hat when performing outdoor activities than the group who did not (3.70±1.84 vs. 3.40±1.94, p=0.034).
Conclusion: To retain youthful skin, it is essential to reduce sun exposure, as this factor can affect the melanin and erythema indices by inducing photoaging. Therefore, avoiding the sun bia proper methods, such as wearing a hat and sunscreen during outdoor activities, is recommended to maintain skin youthfulness. (Korean J Dermatol 2022;60(4): 201∼208)

KCI등재 SCOPUS

2대상포진 예방접종이 고령에서 발생하는 대상포진의 임상양상 및 경과에 미치는 영향: 단일기관의 5년간 후향적 연구

저자 : 김중호 ( Joong Ho Kim ) , 이수경 ( Soo Kyung Lee ) , 김명신 ( Myoung Shin Kim ) , 이운하 ( Un Ha Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 209-219 (11 pages)

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Background: Herpes zoster (HZ) is a neurocutaneous disease caused by reactivation of the varicella zoster virus after primary infection. In Korea, it is recommended that all adults aged >60 be vaccinated against HZ. However, breakthrough infection with HZ can occur infrequently in vaccinated individuals.
Objective: This study aimed to investigate the effects of the HZ vaccine on the clinical manifestations and courses of HZ in immunocompetent elderly individuals aged 60 years and older.
Methods: Among 848 immunocompetent HZ patients, 52 were vaccinated and 796 were unvaccinated. From this cohort, we chose 156 unvaccinated patients through a 1:3 propensity score matching analysis using three parameters; age, sex, and involved dermatome. We subsequently compared the clinical manifestations and courses between the vaccinated (n=52) and unvaccinated (n=156) groups.
Results: The vaccinated group had a lower peak numeric rating scale pain score and a lower rate of consultation with the pain control clinic than the opposite. Additionally, mild skin lesions without vesicles were more frequent in the vaccinated group than in the opposite. The vaccinated group had a shorter duration of total follow-up, shorter antiviral treatment period, lower admission rate, and shorter hospital stay than the opposite. Although postherpetic neuralgia occurred more frequently in the unvaccinated group than in the unvaccinated group, the incidences of other HZ-related complications showed no significant difference between the two groups.
Conclusion: Despite the possibility of breakthrough infection, the HZ vaccine should be recommended in the elderly as it can weaken the clinical features and course of the disease. (Korean J Dermatol 2022;60(4):209∼219)

KCI등재 SCOPUS

3건선관절염을 동반한 중등증 및 중증 건선 환자에서 Secukinumab의 건강관련 삶의 질 개선 효과에 관한 후향적 연구

저자 : 홍용준 ( Yong Jun Hong ) , 고강민 ( Gang Min Go ) , 김미리 ( Miri Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 220-227 (8 pages)

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Background: Psoriasis is a relapsing inflammatory skin disorder that can affect the nails and joints. Psoriatic arthritis (PsA) occurs in up to 30% of patients with psoriasis, leading to chronic articular pain, and impairing quality of life. Secukinumab is a human monoclonal antibody targeting interleukin-17A that has been shown to effectively improve the clinical signs and symptoms of PsA.
Objective: To evaluate the effect of secukinumab on health-related quality of life (HRQOL) in Korean PsA patients.
Methods: We retrospectively investigated the medical records and psoriasis area and severity index (PASI) scores of 13 patients with PsA who completed the psoriatic arthritis impact of disease 12-item questionnaire (PsAID-12) before and 3 months after receiving secukinumab treatment between October 2019 and August 2021 in Yeouido St. Mary's Hospital.
Results: At week 12, significant reductions in the total and each item PsAID-12 and mean PASI score were observed (p<0.01). The mean decrease of total PsAID-12 score was 4.8 (95% confidence interval [CI], 3.74∼5.86), with the greatest improvement observed in the item of 'embarrassment' (7.15; 95% CI, 5.59∼8.72). Of the 13 patients, 11 (84.6%) and 5 (38.5%) achieved PASI75 and PASI90 response, respectively.
Conclusion: This study showed that secukinumab improves the HRQOL of patients with PsA, implying a positive influence of secukinumab on patients' physical and mental status in a real-world clinical setting. (Korean J Dermatol 2022;60(4):220∼227)

KCI등재 SCOPUS

4The Importance of Ultrasonography in the Diagnosis of Epidermal Cysts and Lipomas in the Field of Dermatology

저자 : Kihyuk Shin , Sang-hyeon Won , Chankue Park , Gun-wook Kim , Hoon-soo Kim , Hyun-chang Ko , Moon-bum Kim , Byung-soo Kim

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 228-234 (7 pages)

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Background: Ultrasonography (US) is a simple and reliable tool that can aid in the diagnosis of benign subcutaneous lesions such as epidermal cysts and lipomas.
Objective: This study aimed to determine the efficacy of US for the differential diagnosis of epidermal cysts and lipomas.
Methods: A retrospective study of 100 patients with epidermal cysts (n=45) or lipomas (n=55) who underwent US and then received a pathological diagnosis in the dermatology department of Pusan National University Hospital was conducted.
Results: US and clinical impressions accurately diagnosed the epidermal cysts in 90.0% and 88.0% of the patients, respectively, and the lipomas in 92.0% and 88.0% of the patients, respectively. US combined with clinical impression significantly increased the diagnostic yield of epidermal cysts (98%) and lipomas (99%). On US, the frequency of posterior acoustic enhancement was higher for the epidermal cysts than for the lipomas (82.2% and 29.1%, respectively; p<0.001), and striated echoes such as internal linear echogenic reflections and dark clefts were more frequently found in the lipomas than in the epidermal cysts (90.9% and 6.7%, respectively; p<0.001).
Conclusion: This study implies that the diagnostic role of US can be greatly enhanced by knowledge of the clinical presentation. (Korean J Dermatol 2022;60(4):228∼234)

KCI등재 SCOPUS

5Anxiety Sensitivity and Psychological Distress in Patients with Rosacea: A Questionnaire-Based Study

저자 : Hyo-eun Kwon , Hye-jin Ahn , Min Kyung Shin

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 235-241 (7 pages)

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Background: Rosacea is a common chronic inflammatory disorder that affects the skin of the central face. Anxiety sensitivity (AS) refers to the fear of sensations and symptoms arising from an expected experience of anxiety. High AS can cause anxiety disorders. Several studies have evaluated depression in patients with rosacea; however, AS has not yet been investigated.
Objective: We aimed to investigate AS, depression, and quality of life in patients with rosacea.
Methods: Eighty-five patients with rosacea and 85 controls (aged>18 years) were enrolled in the study. The severity of rosacea was evaluated according to the standard guidelines of the National Rosacea Society. Patients with rosacea and controls were asked to complete the Korean version of the anxiety sensitivity index-revised (ASI-R), beck depression inventory (BDI), and dermatology life quality index (DLQI).
Results: The ASI, BDI, and DLQI scores were significantly higher in patients with rosacea than in controls (p< 0.001). In particular, the cardiovascular subscale of the ASI was significantly increased in patients with rosacea. The ASI and BDI scores were significantly correlated. DLQI scores were weakly correlated with ASI compared with BDI scores in patients with rosacea.
Conclusion: Our study is the first to report that AS is elevated in patients with rosacea. It is necessary to consider the anxiety-related symptoms of patients with rosacea, as they may benefit from psychological intervention to alleviate distress. (Korean J Dermatol 2022;60(4):235∼241)

KCI등재 SCOPUS

6A Study on the Correlation of Skin Types with Genetic Factors and Environmental Factors in Koreans

저자 : Kui Young Park , Jun Ki Hong , Sun Hye Shin , Young Gue Koh , Hye Sung Han , Nam Ju Moon , Gun Young Ahn , Seong Jun Seo

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 242-253 (12 pages)

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Background: The Baumann skin type (BST) classification provides a new approach for clinical care of dermatologic patients.
Objective: To investigate the correlation of skin types with genetic factors and environmental factors that have an important influence on Korean skin by comparing and analyzing the correlation between phenotype and genotype.
Methods: From July to October 2016, 774 adults who visited the one online shopping mall were subjected to skin BST questionnaire and gene single-nucleotide polymorphism (SNP) tests. Oral epithelial cells of the subjects were collected using a Genoplan DNA analysis kit, and 14 genes were analyzed by a genetic analysis agency (Genoplan Inc., Fukuoka, Japan).
Results: The most abundant skin type was OSNT (oily, sensitive, non-pigmented, tight) observed in 205 participants (26.5%). Of the filaggrin (FLG) SNPs, 143 participants (18.5%) had the GG (good) SNP; 391 (50.5%), GA (normal) SNP; and 240 (31.0%), AA (poor) SNP. Among those whose FLG SNP was GG (good), 121 (84.6%) were sensitive and 22 (15.4%) were resistant. Of those whose filaggrin (FLG) SNP was GA (normal), 337 (86.2%) were sensitive and 54 (13.8%) were resistant. Of those whose FLG SNP was AA (poor), 213 (88.8%) were sensitive and 27 (11.3%) were resistant. There was also a statistically significant difference in the fruit-vegetable consumption and use of a sunbathing bed between sensitive and resistant type in the groups that classified the FLG SNP as GA.
Conclusion: This is the first study to investigate the association of BST with genetic factors and environmental factors. (Korean J Dermatol 2022;60(4):242∼253)

KCI등재 SCOPUS

7전완부의 덩이로 발견된 근육내 전이성 투명세포신세포암 1예

저자 : 최연구 ( Yeon-gu Choi ) , 이현주 ( Heun Joo Lee ) , 김원석 ( Won-serk Kim ) , 이가영 ( Ga-young Lee ) , 최영준 ( Young Jun Choi )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 254-257 (4 pages)

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Cutaneous metastases from renal cell carcinoma (RCC) present as rapidly growing erythematous or purple-round nodules. An 88-year-old male presented with a solitary, deep-seated firm mass on his left forearm that had persisted for 3 years. Ultrasonography revealed an hypervascular mass with rich vessels. Magnetic resonance imaging revealed a 1.6×1.6×3.3 cm sized, high T2-weighted signal intensity mass at brachioradialis muscle. Histopathologic examination revealed cells with atypical, pleomorphic, oval to spindle-shaped nuclei, and clear cytoplasm with an alveolar pattern within an unencapsulated, lobulated mass. Immunohistochemical analysis showed that the tumor cells were positive for PAX8, CD10, epithelial membrane antigen, and vimentin. Ultrasonography of the urinary tract revealed a lesion suspected to be RCC, which was thought to be the primary tumor. As our patient showed peculiar clinical symptoms and the primary tumor was later diagnosed as a metastatic lesion inversely, we report a rare case of metastatic RCC with an intramuscular mass on the forearm. (Korean J Dermatol 2022;60(4):254∼257)

KCI등재 SCOPUS

8가족력이 있으면서 임상적 진단이 어려웠던 결절흑색종 1예

저자 : 정서미곤 ( Seo Mi Gon Jeong ) , 윤태진 ( Tae Jin Yoon )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 258-261 (4 pages)

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Nodular melanoma is a malignant melanoma which presents as blackish-brown or colorless nodules. Nodular melanoma shows rapid growth compared to other melanoma subtypes, and often exhibits clinical features that do not correspond to the ABCD rules, which is key in differentiating melanoma. This makes nodular melanoma difficult to differentiate from the initially suspected melanoma. As such, diagnosis of nodular melanoma is commonly delayed, and is therefore often identified at an advanced stage. Here, we report a case of nodular melanoma in a young man with a family history of melanoma. We emphasize the importance of early diagnosis through biopsy for malignant melanoma, which is difficult to differentiate based on clinical features. (Korean J Dermatol 2022;60(4):258∼261)

KCI등재 SCOPUS

9면역기능 정상 성인에서 겨드랑 부위에 발생한 모낭염 양상의 전염성 연속종

저자 : 김동성 , 허재영 , 박태흠 , 김우일 , 조문균 , 김수영

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 262-263 (2 pages)

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KCI등재 SCOPUS

10저절로 호전된 원인 불명의 붉은 에크린색한증 1예

저자 : 이상균 , 홍승필

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 4호 발행 연도 : 2022 페이지 : pp. 264-265 (2 pages)

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KCI등재SCOUPUS

1악성 흑색종에 대한 한국어 유튜브 동영상의 질 평가

저자 : 허근영 ( Keunyoung Hur ) , 하은서 ( Eun-seo Ha ) , 김동효 ( Dong Hyo Kim ) , 송원지 ( Won Ji Song ) , 문제호 ( Je-ho Mun )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 143-150 (8 pages)

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Background: Disseminating public knowledge on malignant melanoma through YouTube is an important way to bridge the gap between physicians and patients. However, videos recorded on this topic in Korea are yet to be evaluated.
Objective: We aimed to evaluate the quality of YouTube videos on malignant melanoma recorded in Korea. We also investigated whether there was a difference in the quality of videos made by medical professionals (subdivided into dermatologists and non-dermatologists) and non-medical personnel.
Methods: We included all videos recorded in Korean by searching YouTube using the keywords “melanoma” or “malignant melanoma”. The search was performed on March 22, 2021. The inclusion criterion was videos in Korean language that contained medical information about malignant melanoma. The characteristics and content information were collected for each video. Video quality (DISCERN, Global Quality Scale [GQS], Journal of the American Medical Association [JAMA] benchmark criteria) was analyzed.
Results: Eighty-five videos met the inclusion criterion for the analysis. Fifty-six (66%) and 29 videos (34%) were made by medical and non-medical personnel, respectively. The videos made by medical professionals significantly contained more of the following information than those made by non-medical personnel: clinical information (p<0.001), symptoms and signs (p=0.001), risk factors (p<0.05), diagnosis (p<0.001). Videos made by medical professionals, videos with a length of more than 5 minutes, or videos with more than 10,000 views had significantly higher quality scores (DISCERN, GQS, JAMA).
Conclusion: Considering that YouTube is being used as a portal for medical information, the participation of medical professionals is essential for providing more accurate information. (Korean J Dermatol 2022;60(3):143∼150)

KCI등재SCOUPUS

2중등도-중증의 한국인 건선 환자에서 Ustekinumab 장기 투여에 따른 효과 및 안전성 연구

저자 : 김연아 ( Yeona Kim ) , 배경남 ( Kyung-nam Bae ) , 손진화 ( Jin-hwa Son ) , 신기혁 ( Kihyuk Shin ) , 김훈수 ( Hoonsoo Kim ) , 고현창 ( Hyun-chang Ko ) , 김문범 ( Moon-bum Kim ) , 신봉석 ( Bong Seok Shin ) , 김병수 ( Byungsoo Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 151-158 (8 pages)

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Background: Ustekinumab is a humanized monoclonal antibody targeting interleukin (IL)-12 and IL-23. Although popular, data on its long-term efficacy and safety in Korean patients with psoriasis are limited.
Objective: To evaluate the long-term efficacy and safety of ustekinumab in Korean patients with psoriasis.
Methods: A retrospective study in patients with moderate-to-severe psoriasis who had been treated with ustekinumab for at least 5 years was conducted. The sex, age, body mass index, medical records, previous psoriasis therapy, psoriasis area and severity index (PASI) scores, and adverse events were evaluated.
Results: Twenty-five patients (median age 47.00 years) had been treated with ustekinumab for 5 years. The mean duration of psoriasis was 19.12±8.45 years, and the treatment duration with ustekinumab was 285.12±8.48 weeks. The baseline PASI was 17.52±7.38. PASI75 was achieved in 84% of the patients at week 28, and 96% of the patients maintained PASI75 during the 5-year follow-up period. Furthermore, 56% of patients reached PASI90 at 28 weeks, and 48% of patients maintained PASI90 for 5 years. No unexpected adverse events other than herpes zoster, herpes simplex, or elevated liver enzymes were reported.
Conclusion: Ustekinumab demonstrated long-lasting efficacy with an acceptable safety profile in Korean patients with moderate-to-severe psoriasis. (Korean J Dermatol 2022;60(3):151∼158)

KCI등재SCOUPUS

3흡입 수포의 체액과 혈청에서 측정한 지질들의 상관성 분석

저자 : 권일주 ( Il Joo Kwon ) , 최승재 ( Sung Jay Choe ) , 정승원 ( Seung Won Jeong ) , 전명수 ( Myungsoo Jun ) , 최응호 ( Eung Ho Choi )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 159-166 (8 pages)

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Background: Several biomarkers are measured in the interstitial fluid (IF) obtained from suction blisters that are used by dermatologists. As abnormal lipid levels can cause health problems, several studies have investigated the composition and distribution of lipids and lipoproteins in IF. However, to date, no study has focused on examining lipid profiles in the postprandial state.
Objective: This study aimed to compare postprandial changes in serum lipid profiles and IF obtained from suction blisters and investigated their correlation.
Methods: Fasting and postprandial levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides were measured in paired serum samples. IF was obtained from suction blisters from 20 healthy men using enzymatic-colorimetric methods.
Results: The IF/serum ratios of TC, HDL-C, and LDL-C remained unchanged postoperatively. Postprandial levels of HDL-C and LDL-C decreased in the serum but not in IF. In both fasting and postprandial states, TC, HDL-C, and LDL-C levels in the serum were positively correlated with those in the IF.
Conclusion: The results of this study showed that lipoprotein cholesterol levels measured from suction blister fluids could be used as a biomarker to predict their serum levels regardless of food intake. Therefore, suction blister fluid sampling can be considered as a method to monitor serum lipid concentrations. (Korean J Dermatol 2022;60(3):159∼166)

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4일차성 호중구성 반흔성 탈모의 임상 및 조직학적 소견에 대한 비교 연구

저자 : 백은주 ( Eun Joo Baek ) , 형진혁 ( Jin Hyeok Hyeong ) , 박은주 ( Eun Joo Park ) , 김광중 ( Kwang Joong Kim ) , 김광호 ( Kwang Ho Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 167-172 (6 pages)

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Background: Folliculitis decalvans and dissecting cellulitis are types of primary neutrophilic cicatricial alopecia characterized by permanent hair loss. Clinicopathological differentiation is poorly described in literature.
Objective: This study aimed to determine the clinicopathological distinction between folliculitis decalvans and dissecting cellulitis.
Methods: A retrospective review was conducted in 45 patients diagnosed with dissecting cellulitis and folliculitis decalvans between 2011 and 2021. We reviewed the clinical features using electronic medical records, clinical photographs, and histopathologic features.
Results: Clinically, middle-aged men with folliculitis decalvans showed polytrichia (80%) and papulopustules (55%), while young men with dissecting cellulitis had deeply seated nodules (84%). Histopathologically, follicular plugging was more frequently observed in dissecting cellulitis (80%) than in folliculitis decalvans (50%). There was a difference in the depth of inflammation between the two types.
Conclusion: A difference in clinical manifestations was observed according to the depth of inflammation. These findings may contribute to the differential diagnosis of primary neutrophilic cicatricial alopecia. (Korean J Dermatol 2022;60(3):167∼172)

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5비전형적인 조직소견을 보인 회음부의 색소성 정중솔기낭종 1예

저자 : 김현희 ( Hyun Hee Kim ) , 명기범 ( Ki Bum Myung ) , 권은선 ( Eun Sun Kwon ) , 정승현 ( Seung Hyun Cheong )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 173-177 (5 pages)

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Median raphe cysts (MRCs) are rare benign lesions that occur as a result of congenital defects during the embryological development of the male genitalia in the fetal period. It can develop anywhere along the midline, from the meatus to the anus. Pigmented MRCs are rare subtypes that contain melanin pigments or melanocytes in the epithelium, and there are only eight such cases reported worldwide. We report herein a case of pigmented MRC in the perineum of a 3-year-old boy. The clinical features include a linear tubular structure and foreign body granuloma at the tip of the linear cystic lesion and rare histological findings of pigmented cuboidal epithelium and squamous epithelium. Immunohistochemical staining revealed strong positivity for c-kit in the pigmented cuboidal epithelium. In this report, we discuss a rare case of pigmented MRC with a mixed type of squamous epithelium and pigmented cuboidal epithelium and review the associated literature. (Korean J Dermatol 2022;60(3):173∼177)

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6Multiple Spider Angiomas as a Predictive Diagnostic Marker of Alcoholic Liver Cirrhosis

저자 : Jun Ki Hong , Hye Sung Han , Sun Hye Shin , Young Gue Koh , Kapsok Li , Beom Joon Kim , Kwang Ho Yoo

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 178-181 (4 pages)

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Spider angioma (SA) may present as solitary or multiple lesions. Studies have shown that approximately 60% of pregnant women and 38% of healthy children have at least one spider telangiectasia. Hence, solitary SA in an otherwise healthy individual does not warrant further workup. However, multiple spider angiomas (MSAs) are usually suggestive of an underlying systemic disease. Physical examination for MSAs has been reported as the most reliable method to diagnose alcoholic liver cirrhosis; the presence of MSAs is more indicative of liver cirrhosis than just the history of alcohol use because a very low proportion of alcohol drinkers among the general population develop liver cirrhosis. We report a case of MSAs in a 42-year-old alcoholic woman suggesting that MSA is reliable indicator and a warning sign of liver cirrhosis, suggesting that further evaluation and management with the department of hepatology is necessary. (Korean J Dermatol 2022;60(3):178∼181)

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7A Drug-Induced Sarcoidosis-Like Reaction in Lung Cancer Patient Treated with Nivolumab and Ipilimumab: A Case Report and Literature Review

저자 : Soo Hyung Kim , Seo Gyeong Lee , Ji Yoon Kim , Hyun Jeong Ju , Gyong Moon Kim , Ji Hae Lee

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 182-185 (4 pages)

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Immune checkpoint inhibitor (ICI), including programmed cell death protein 1 and cytotoxic T-lymphocyte-associated protein 4 inhibitors, has emerged as a pillar in the management of advanced malignancies. A drug-induced sarcoidosis-like reaction (DISR) is a rare cutaneous adverse event of ICI. A 47-year-old male presented with one-month history of a solitary erythematous nodule on his forehead. He had been diagnosed with metastatic adenocarcinoma of the lung and was treated with nivolumab and ipilimumab for three months. Histological findings revealed multinucleated giant cells forming non-caseating granulomas with moderate peripheral lymphocyte infiltration in the dermis. Also, new hilar lymphadenopathy of the lung was identified in a systemic evaluation. Given the temporal relationship with ICI treatment, the final diagnosis was ICI-induced sarcoidosis-like reaction. To our knowledge, this is the first report of a case of DISR that developed following ICI treatment in the dermatologic literature in Korea. (Korean J Dermatol 2022;60(3):182∼185)

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8Multiple Warty Dyskeratomas of the Scrotum: A Case Report and Review of the Literature

저자 : Joon Ho Son , Yeong Ho Kim , Ju Hee Han , Chul Hwan Bang , Ji Hyun Lee , Young Min Park

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 186-189 (4 pages)

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Warty dyskeratoma (WD) is an uncommon skin tumor that histologically presents as focal acantholysis and dyskeratosis and is a common finding among acantholytic diseases such as Darier's disease. WD most commonly occurs on the head or neck of adults as an isolated papule or nodule. To our knowledge, only 6 cases of WD in the genital area have been previously reported in the literature, and no case have occurred on the scrotum to date. We report the first case of multiple WD that occurred on the scrotum successfully treated with 0.025% tretinoin cream. A 55-year-old male presented with asymptomatic, multiple, 0.1∼0.2-cm-sized, skin-colored papules on the scrotum for the previous 6 months. A skin punch biopsy and human papillomavirus (HPV) polymerase chain reaction test were performed for a clinical suspicion of genital warts or bowenoid papulosis. The histopathologic examination showed cup-shaped epidermal invaginations with central keratotic plug. Prominent villi, acantholytic clefting and corps ronds were also shown. The patient tested negative for HPV and was diagnosed with WD with typical pathologic findings. The patient was treated with 0.025% tretinoin cream for 2 weeks, and the lesions decreased in both size and number. (Korean J Dermatol 2022;60(3):186∼189)

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9급성 골수성 백혈병 재발과 연관된 결절홍반 1예

저자 : 윤지상 , 배경남 , 손진화 , 김훈수 , 고현창 , 김병수 , 김문범 , 신기혁

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 190-191 (2 pages)

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10모낭 및 피지선 유도를 동반한 위축성 피부섬유종 1예

저자 : 한유진 , 김혜성 , 조상현 , 이정덕 , 우유리

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 3호 발행 연도 : 2022 페이지 : pp. 192-193 (2 pages)

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