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한국센서학회> 센서학회지> Lightweight image classifier for CIFAR-10

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Lightweight image classifier for CIFAR-10

Akshay Kumar Sharma , Amrita Rana , Kyung Ki Kim
  • : 한국센서학회
  • : 센서학회지 30권5호
  • : 연속간행물
  • : 2021년 09월
  • : 286-289(4pages)
센서학회지

DOI


목차

1. INTRODUCTION
2. Proposed Method
3. RESULTS AND DISCUSSIONS
4. CONCLUSION
ACKNOWLEDGMENT
REFERENCES

키워드 보기


초록 보기

Image classification is one of the fundamental applications of computer vision. It enables a system to identify an object in an image. Recently, image classification applications have broadened their scope from computer applications to edge devices. The convolutional neural network (CNN) is the main class of deep learning neural networks that are widely used in computer tasks, and it delivers high accuracy. However, CNN algorithms use a large number of parameters and incur high computational costs, which hinder their implementation in edge hardware devices. To address this issue, this paper proposes a lightweight image classifier that provides good accuracy while using fewer parameters. The proposed image classifier diverts the input into three paths and utilizes different scales of receptive fields to extract more feature maps while using fewer parameters at the time of training. This results in the development of a model of small size. This model is tested on the CIFAR-10 dataset and achieves an accuracy of 90% using .26M parameters. This is better than the state-of-the-art models, and it can be implemented on edge devices.

UCI(KEPA)

간행물정보

  • : 공학분야  > 전기공학
  • : KCI등재
  • :
  • : 격월
  • : 1225-5475
  • : 2093-7563
  • : 학술지
  • : 연속간행물
  • : 1992-2021
  • : 1875


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30권5호(2021년 09월) 수록논문
최근 권호 논문
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KCI등재

1Effect of corrugation structure and shape on the mechanical stiffness of the diaphragm

저자 : Junsoo Kim , Wonkyu Moon

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 273-278 (6 pages)

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Here, we studied the change in the mechanical stiffness of a diaphragm according to the corrugation pattern. The diaphragm consists of a silicon oxide and nitride double layer; a corrugation pattern was formed by dry etching, and the diaphragm was released by wet etching. The fabrication of the thin film was verified using focused ion beam and scanning electron microscopy images. The mechanical stiffness of the diaphragm was obtained by measuring the surface vibration using a laser Doppler vibrometer while applying external sound pressure. Flat squares, diaphragms with square corrugations, and circular corrugation patterns were measured and compared. The stiffness of the diaphragm with a corrugation structure was found to be smaller than that without a corrugation structure; in particular, circular corrugation showed a better effect because of the high symmetry. Furthermore, the effect of corrugation was theoretically predicted. The proposed corrugated diaphragm showed comparable flexibility with the state-of-the-art MEMS microphone diaphragm.

KCI등재

2Structural, morphological, optical, and photosensing properties of Cs2TeI6 thin film synthesized by two-step dry process

저자 : Phung Dinh Hoat , Vo Van Khoe , Sung-hoon Bae , Hyo-jun Lim , Pham Tien Hung , Young-woo Heo

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 279-285 (7 pages)

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Recently, cesium tellurium iodine (Cs2TeI6) has emerged as an inorganic halide perovskite material with potential application in optoelectronic devices due to its high absorption coefficient, suitable bandgap and because it consists of nontoxic and earth-abundant elements. However, studies on its fabrication process as well as photoresponse characteristics are limited. In this study, a simple and effective method is introduced for the synthesis of Cs2TeI6 thin films by a two-step dry process. A Cs2TeI6-based lateral photosensor was fabricated, and its photoresponse characteristics were explored under laser illuminations of four different wavelengths in the visible range: 405, 450, 520, and 655 nm. The initial photosensing results suggest potential application and can lead to more promising studies of Cs2TeI6 film in optoelectronics.

KCI등재

3Lightweight image classifier for CIFAR-10

저자 : Akshay Kumar Sharma , Amrita Rana , Kyung Ki Kim

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 286-289 (4 pages)

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초록보기

Image classification is one of the fundamental applications of computer vision. It enables a system to identify an object in an image. Recently, image classification applications have broadened their scope from computer applications to edge devices. The convolutional neural network (CNN) is the main class of deep learning neural networks that are widely used in computer tasks, and it delivers high accuracy. However, CNN algorithms use a large number of parameters and incur high computational costs, which hinder their implementation in edge hardware devices. To address this issue, this paper proposes a lightweight image classifier that provides good accuracy while using fewer parameters. The proposed image classifier diverts the input into three paths and utilizes different scales of receptive fields to extract more feature maps while using fewer parameters at the time of training. This results in the development of a model of small size. This model is tested on the CIFAR-10 dataset and achieves an accuracy of 90% using .26M parameters. This is better than the state-of-the-art models, and it can be implemented on edge devices.

KCI등재

4Robust architecture search using network adaptation

저자 : Amrita Rana , Kyung Ki Kim

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 290-294 (5 pages)

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Experts have designed popular and successful model architectures, which, however, were not the optimal option for different scenarios. Despite the remarkable performances achieved by deep neural networks, manually designed networks for classification tasks are the backbone of object detection. One major challenge is the ImageNet pre-training of the search space representation; moreover, the searched network incurs huge computational cost. Therefore, to overcome the obstacle of the pre-training process, we introduce a network adaptation technique using a pre-trained backbone model tested on ImageNet. The adaptation method can efficiently adapt the manually designed network on ImageNet to the new object-detection task. Neural architecture search (NAS) is adopted to adapt the architecture of the network. The adaptation is conducted on the MobileNetV2 network. The proposed NAS is tested using SSDLite detector. The results demonstrate increased performance compared to existing network architecture in terms of search cost, total number of adder arithmetics (Madds), and mean Average Precision(mAP). The total computational cost of the proposed NAS is much less than that of the State Of The Art (SOTA) NAS method.

KCI등재

5CMOS binary image sensor with high-sensitivity metal-oxide semiconductor field-effect transistor-type photodetector for high-speed imaging

저자 : Juneyoung Jang , Wonbin Heo , Jaesung Kong , Young-mo Kim , Jang-kyoo Shin

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 295-299 (5 pages)

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In this study, we present a complementary metal-oxide-semiconductor (CMOS) binary image sensor. It can shoot an object rotating at a high-speed by using a gate/body-tied (GBT) p-channel metal-oxide-semiconductor field-effect transistor (PMOSFET)-type photodetector. The GBT PMOSFET-type photodetector amplifies the photocurrent generated by light. Therefore, it is more sensitive than a standard N+/P-substrate photodetector. A binary operation is installed in a GBT PMOSFET-type photodetector with high-sensitivity characteristics, and the high-speed operation is verified by the output image. The binary operations circuit comprise a comparator and memory of 1- bit. Thus, the binary CMOS image sensor does not require an additional analog-to-digital converter. The binary CMOS image sensor is manufactured using a standard CMOS process, and its high- speed operation is verified experimentally.

KCI등재

6DCGAN을 이용한 잡육에서의 바늘 검출

저자 : 장원재 ( Won-jae Jang ) , 차윤석 ( Yun-seok Cha ) , 금예은 ( Ye-eun Keum ) , 이예진 ( Ye-jin Lee ) , 김정도 ( Jeong-do Kim )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 300-308 (9 pages)

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Usually, during slaughter, the meat is divided into large chunks by part after deboning. The meat chunks are inspected for the presence of needles with an X-ray scanner. Although needles in the meat chunks are easily detectable, they can also be found in trimmings and meat offals, where meat skins, fat chunks, and pieces of meat from different parts get agglomerated. Detection of needles in trimmings and meat offals becomes challenging because of many needle-like patterns that are detected by the X-ray scanner. This problem can be solved by learning the trimmings or meat offals using deep learning. However, it is not easy to collect a large number of learning patterns in trimmings or meat offals. In this study, we demonstrate the use of deep convolutional generative adversarial network (DCGAN) to create fake images of trimmings or meat offals and train them using a convolution neural network (CNN).

KCI등재

7유기발광소자에 적용 가능한 NiOx 기반의 정공주입층 연구

저자 : 김준모 ( Junmo Kim ) , 김예진 ( Yejin Gim ) , 이원호 ( Wonho Lee ) , 이동구 ( Donggu Lee )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 309-313 (5 pages)

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Organic semiconductors have received tremendous attention for their research because of their tunable electrical and optical properties that can be achieved by changing their molecular structure. However, organic materials are inherently unstable in the presence of oxygen and moisture. Therefore, it is necessary to develop moisture and air stable semiconducting materials that can replace conventional organic semiconductors. In this study, we developed a NiOx thin film through a solution process. The electrical characteristics of the NiOx thin film, depending on the thermal annealing temperature and UV-ozone treatment, were determined by applying them to the hole injection layer of an organic light-emitting diode. A high annealing temperature of 500 ℃ and UV-ozone treatment enhanced the conductivity of the NiOx thin films. The optimized NiOx exhibited beneficial hole injection properties comparable those of 1,4,5,8,9,11-hexaazatriphenylene hexacarbonitrile (HAT-CN), a conventional organic hole injection layer. As a result, both devices exhibited similar power efficiencies and the comparable electroluminescent spectra. We believe that NiOx could be a potential solution which can provide robustness to conventional organic semiconductors.

KCI등재

8가변 파장형 적외선 가스 센서에 의한 생체표지자 분석

저자 : 이승환 ( Seung Hwan Yi )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 314-319 (6 pages)

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In this study, biomarkers were analyzed and segmented using tunable infrared gas sensors after performing the principal component analysis. The free spectral range of the device under test (DUT) was around 30 nm and DUT-5580 yielded the highest output voltage property among the others. The biomarkers (isoprophyl alcohol, ethanol, methanol, and acetone solutions) were sequentially mixed with deionized water and their mists were carried into the gas chamber using high-purity nitrogen gas. A total of 17 different mixed gases were tested with three tunable infrared gas sensors, namely DUT-3144, DUT-5580, and DUT-8010. DUT-8010 resolved the infrared absorption spectra of whole mixed gases. Based on the principal component analysis with each DUT and their combinations, each mixed gas and the trends in increasing gas concentration could be well analyzed when the contributions of the eigenvalues of the first and second were higher than 70% and 10%, respectively, and their sum was greater than 90%.

KCI등재

9이산화티타늄 광촉매를 이용한 총유기탄소 분석방법

저자 : 박범근 ( Buem Keun Park ) , 김성미 ( Sung Mi Kim ) , 이영진 ( Young-jin Lee ) , 백종후 ( Jong-hoo Paik ) , 신정희 ( Jeong Hee Shin )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 320-325 (6 pages)

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Biochemical oxygen demand (BOD) and chemical oxygen demand (COD) methods are conventional analytical methods to analyze water quality. Both of these methods are technically indirect measurement methods, require complicated preconditions, and are timeconsuming. On the other hand, the total organic carbon (TOC) method is a direct and fast measurement method which is more intuitive and accurate than the BOD and COD methods. However, general TOC analysis methods involve complicated processes and high power consumption owing to the process of phase transition from liquid to gas by a high-temperature heater. Furthermore, periodic consumables are also required for the removal of inorganic carbon (IC). Titanium dioxide (TiO2) is one of the most suitable photocatalysts for simple processes. Its usage involves low power consumption because it only reacts with the organic carbon (OC) without the requirement of any other reagents and extra processes. We investigated a TiO2 photocatalyst-based TOC analysis for simple and affordable products. TiO2-coated fiber substrate maintained under carbon included water was exposed to ultraviolet (UV) radiation of wavelength 365 nm. This method is suitable for the real-time monitoring of water pollution because of its fast reaction time. Its linear property is also sufficient to match the real value.

KCI등재

10소 혈청 알부민의 금 표면 플라즈몬 공명 칩과의 반응에 대한 pH의 영향

저자 : 손영수 ( Young-soo Sohn )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 326-330 (5 pages)

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Reactions between gold (Au) surface plasmon resonance (SPR) chips and bovine serum albumin (BSA) dissolved in solutions of different pH were investigated. The charge on the BSA depends on the pH of the solution in which it is dissolved. Thus, dissolving BSA in different pH solutions resulted in different charges of BSA. Among the BSA dissolved in solutions with pH 4.01, 7.4, and 10.01, the SPR response was the highest for BSA dissolved in the solution of pH 4.01. To eliminate the response variation owing to the difference in the refractive indices of the solutions, phosphate buffered saline (PBS) was injected into the system after the reaction of BSA with the Au SPR chip had happened. In this case too, the BSA dissolved in the solution with pH 4.01 exhibited the highest response. This may be attributed to the non-uniform distribution of ionic patches on the BSA, which can induce electrostatic attraction to the surface even though BSA has a positive charge at pH 4.01, and the absolute values of the net charge of BSA at pH 4.01 and 7.4 were very close.

12
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KCI등재

1Effect of corrugation structure and shape on the mechanical stiffness of the diaphragm

저자 : Junsoo Kim , Wonkyu Moon

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 273-278 (6 pages)

다운로드

(기관인증 필요)

초록보기

Here, we studied the change in the mechanical stiffness of a diaphragm according to the corrugation pattern. The diaphragm consists of a silicon oxide and nitride double layer; a corrugation pattern was formed by dry etching, and the diaphragm was released by wet etching. The fabrication of the thin film was verified using focused ion beam and scanning electron microscopy images. The mechanical stiffness of the diaphragm was obtained by measuring the surface vibration using a laser Doppler vibrometer while applying external sound pressure. Flat squares, diaphragms with square corrugations, and circular corrugation patterns were measured and compared. The stiffness of the diaphragm with a corrugation structure was found to be smaller than that without a corrugation structure; in particular, circular corrugation showed a better effect because of the high symmetry. Furthermore, the effect of corrugation was theoretically predicted. The proposed corrugated diaphragm showed comparable flexibility with the state-of-the-art MEMS microphone diaphragm.

KCI등재

2Structural, morphological, optical, and photosensing properties of Cs2TeI6 thin film synthesized by two-step dry process

저자 : Phung Dinh Hoat , Vo Van Khoe , Sung-hoon Bae , Hyo-jun Lim , Pham Tien Hung , Young-woo Heo

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 279-285 (7 pages)

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(기관인증 필요)

초록보기

Recently, cesium tellurium iodine (Cs2TeI6) has emerged as an inorganic halide perovskite material with potential application in optoelectronic devices due to its high absorption coefficient, suitable bandgap and because it consists of nontoxic and earth-abundant elements. However, studies on its fabrication process as well as photoresponse characteristics are limited. In this study, a simple and effective method is introduced for the synthesis of Cs2TeI6 thin films by a two-step dry process. A Cs2TeI6-based lateral photosensor was fabricated, and its photoresponse characteristics were explored under laser illuminations of four different wavelengths in the visible range: 405, 450, 520, and 655 nm. The initial photosensing results suggest potential application and can lead to more promising studies of Cs2TeI6 film in optoelectronics.

KCI등재

3Lightweight image classifier for CIFAR-10

저자 : Akshay Kumar Sharma , Amrita Rana , Kyung Ki Kim

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 286-289 (4 pages)

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(기관인증 필요)

초록보기

Image classification is one of the fundamental applications of computer vision. It enables a system to identify an object in an image. Recently, image classification applications have broadened their scope from computer applications to edge devices. The convolutional neural network (CNN) is the main class of deep learning neural networks that are widely used in computer tasks, and it delivers high accuracy. However, CNN algorithms use a large number of parameters and incur high computational costs, which hinder their implementation in edge hardware devices. To address this issue, this paper proposes a lightweight image classifier that provides good accuracy while using fewer parameters. The proposed image classifier diverts the input into three paths and utilizes different scales of receptive fields to extract more feature maps while using fewer parameters at the time of training. This results in the development of a model of small size. This model is tested on the CIFAR-10 dataset and achieves an accuracy of 90% using .26M parameters. This is better than the state-of-the-art models, and it can be implemented on edge devices.

KCI등재

4Robust architecture search using network adaptation

저자 : Amrita Rana , Kyung Ki Kim

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 290-294 (5 pages)

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초록보기

Experts have designed popular and successful model architectures, which, however, were not the optimal option for different scenarios. Despite the remarkable performances achieved by deep neural networks, manually designed networks for classification tasks are the backbone of object detection. One major challenge is the ImageNet pre-training of the search space representation; moreover, the searched network incurs huge computational cost. Therefore, to overcome the obstacle of the pre-training process, we introduce a network adaptation technique using a pre-trained backbone model tested on ImageNet. The adaptation method can efficiently adapt the manually designed network on ImageNet to the new object-detection task. Neural architecture search (NAS) is adopted to adapt the architecture of the network. The adaptation is conducted on the MobileNetV2 network. The proposed NAS is tested using SSDLite detector. The results demonstrate increased performance compared to existing network architecture in terms of search cost, total number of adder arithmetics (Madds), and mean Average Precision(mAP). The total computational cost of the proposed NAS is much less than that of the State Of The Art (SOTA) NAS method.

KCI등재

5CMOS binary image sensor with high-sensitivity metal-oxide semiconductor field-effect transistor-type photodetector for high-speed imaging

저자 : Juneyoung Jang , Wonbin Heo , Jaesung Kong , Young-mo Kim , Jang-kyoo Shin

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 295-299 (5 pages)

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In this study, we present a complementary metal-oxide-semiconductor (CMOS) binary image sensor. It can shoot an object rotating at a high-speed by using a gate/body-tied (GBT) p-channel metal-oxide-semiconductor field-effect transistor (PMOSFET)-type photodetector. The GBT PMOSFET-type photodetector amplifies the photocurrent generated by light. Therefore, it is more sensitive than a standard N+/P-substrate photodetector. A binary operation is installed in a GBT PMOSFET-type photodetector with high-sensitivity characteristics, and the high-speed operation is verified by the output image. The binary operations circuit comprise a comparator and memory of 1- bit. Thus, the binary CMOS image sensor does not require an additional analog-to-digital converter. The binary CMOS image sensor is manufactured using a standard CMOS process, and its high- speed operation is verified experimentally.

KCI등재

6DCGAN을 이용한 잡육에서의 바늘 검출

저자 : 장원재 ( Won-jae Jang ) , 차윤석 ( Yun-seok Cha ) , 금예은 ( Ye-eun Keum ) , 이예진 ( Ye-jin Lee ) , 김정도 ( Jeong-do Kim )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 300-308 (9 pages)

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Usually, during slaughter, the meat is divided into large chunks by part after deboning. The meat chunks are inspected for the presence of needles with an X-ray scanner. Although needles in the meat chunks are easily detectable, they can also be found in trimmings and meat offals, where meat skins, fat chunks, and pieces of meat from different parts get agglomerated. Detection of needles in trimmings and meat offals becomes challenging because of many needle-like patterns that are detected by the X-ray scanner. This problem can be solved by learning the trimmings or meat offals using deep learning. However, it is not easy to collect a large number of learning patterns in trimmings or meat offals. In this study, we demonstrate the use of deep convolutional generative adversarial network (DCGAN) to create fake images of trimmings or meat offals and train them using a convolution neural network (CNN).

KCI등재

7유기발광소자에 적용 가능한 NiOx 기반의 정공주입층 연구

저자 : 김준모 ( Junmo Kim ) , 김예진 ( Yejin Gim ) , 이원호 ( Wonho Lee ) , 이동구 ( Donggu Lee )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 309-313 (5 pages)

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Organic semiconductors have received tremendous attention for their research because of their tunable electrical and optical properties that can be achieved by changing their molecular structure. However, organic materials are inherently unstable in the presence of oxygen and moisture. Therefore, it is necessary to develop moisture and air stable semiconducting materials that can replace conventional organic semiconductors. In this study, we developed a NiOx thin film through a solution process. The electrical characteristics of the NiOx thin film, depending on the thermal annealing temperature and UV-ozone treatment, were determined by applying them to the hole injection layer of an organic light-emitting diode. A high annealing temperature of 500 ℃ and UV-ozone treatment enhanced the conductivity of the NiOx thin films. The optimized NiOx exhibited beneficial hole injection properties comparable those of 1,4,5,8,9,11-hexaazatriphenylene hexacarbonitrile (HAT-CN), a conventional organic hole injection layer. As a result, both devices exhibited similar power efficiencies and the comparable electroluminescent spectra. We believe that NiOx could be a potential solution which can provide robustness to conventional organic semiconductors.

KCI등재

8가변 파장형 적외선 가스 센서에 의한 생체표지자 분석

저자 : 이승환 ( Seung Hwan Yi )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 314-319 (6 pages)

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In this study, biomarkers were analyzed and segmented using tunable infrared gas sensors after performing the principal component analysis. The free spectral range of the device under test (DUT) was around 30 nm and DUT-5580 yielded the highest output voltage property among the others. The biomarkers (isoprophyl alcohol, ethanol, methanol, and acetone solutions) were sequentially mixed with deionized water and their mists were carried into the gas chamber using high-purity nitrogen gas. A total of 17 different mixed gases were tested with three tunable infrared gas sensors, namely DUT-3144, DUT-5580, and DUT-8010. DUT-8010 resolved the infrared absorption spectra of whole mixed gases. Based on the principal component analysis with each DUT and their combinations, each mixed gas and the trends in increasing gas concentration could be well analyzed when the contributions of the eigenvalues of the first and second were higher than 70% and 10%, respectively, and their sum was greater than 90%.

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9이산화티타늄 광촉매를 이용한 총유기탄소 분석방법

저자 : 박범근 ( Buem Keun Park ) , 김성미 ( Sung Mi Kim ) , 이영진 ( Young-jin Lee ) , 백종후 ( Jong-hoo Paik ) , 신정희 ( Jeong Hee Shin )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 320-325 (6 pages)

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Biochemical oxygen demand (BOD) and chemical oxygen demand (COD) methods are conventional analytical methods to analyze water quality. Both of these methods are technically indirect measurement methods, require complicated preconditions, and are timeconsuming. On the other hand, the total organic carbon (TOC) method is a direct and fast measurement method which is more intuitive and accurate than the BOD and COD methods. However, general TOC analysis methods involve complicated processes and high power consumption owing to the process of phase transition from liquid to gas by a high-temperature heater. Furthermore, periodic consumables are also required for the removal of inorganic carbon (IC). Titanium dioxide (TiO2) is one of the most suitable photocatalysts for simple processes. Its usage involves low power consumption because it only reacts with the organic carbon (OC) without the requirement of any other reagents and extra processes. We investigated a TiO2 photocatalyst-based TOC analysis for simple and affordable products. TiO2-coated fiber substrate maintained under carbon included water was exposed to ultraviolet (UV) radiation of wavelength 365 nm. This method is suitable for the real-time monitoring of water pollution because of its fast reaction time. Its linear property is also sufficient to match the real value.

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10소 혈청 알부민의 금 표면 플라즈몬 공명 칩과의 반응에 대한 pH의 영향

저자 : 손영수 ( Young-soo Sohn )

발행기관 : 한국센서학회 간행물 : 센서학회지 30권 5호 발행 연도 : 2021 페이지 : pp. 326-330 (5 pages)

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Reactions between gold (Au) surface plasmon resonance (SPR) chips and bovine serum albumin (BSA) dissolved in solutions of different pH were investigated. The charge on the BSA depends on the pH of the solution in which it is dissolved. Thus, dissolving BSA in different pH solutions resulted in different charges of BSA. Among the BSA dissolved in solutions with pH 4.01, 7.4, and 10.01, the SPR response was the highest for BSA dissolved in the solution of pH 4.01. To eliminate the response variation owing to the difference in the refractive indices of the solutions, phosphate buffered saline (PBS) was injected into the system after the reaction of BSA with the Au SPR chip had happened. In this case too, the BSA dissolved in the solution with pH 4.01 exhibited the highest response. This may be attributed to the non-uniform distribution of ionic patches on the BSA, which can induce electrostatic attraction to the surface even though BSA has a positive charge at pH 4.01, and the absolute values of the net charge of BSA at pH 4.01 and 7.4 were very close.

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