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조선대학교 치의학연구원> Oral Biology Research (OBR)> Evaluation of superoxide dismutase 3, heme-oxygenase, and myeloperoxidase expression levels associated with oxidative stress in chronic periodontitis

KCI등재

Evaluation of superoxide dismutase 3, heme-oxygenase, and myeloperoxidase expression levels associated with oxidative stress in chronic periodontitis

Yong Yoon , Hyerin Kim , Jae Mok Lee
  • : 조선대학교 치의학연구원
  • : Oral Biology Research (OBR) 45권3호
  • : 연속간행물
  • : 2021년 09월
  • : 99-106(8pages)
Oral Biology Research (OBR)

DOI


목차

Introduction
Materials and Methods
Results
Discussion
Conflicts of Interest
ORCID
References

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초록 보기

This study aimed to investigate the expression levels of antioxidative enzymes such as superoxide dismutase 3 (SOD3), heme-oxygenase (HO), and myeloperoxidase (MPOs), which are known to be associated with oxidative stress induction in chronic inflammatory conditions like periodontitis. We compared the expression levels of SOD3, HO, and MPO in the periodontal tissues of healthy individuals with those in the periodontal tissues of chronic periodontitis patients. The expression levels of SOD3, HO, and MPO were determined by Western blot technique, and the data were statistically analyzed. The expression levels of SOD3 and HO increased in periodontitis patients compared with those in healthy controls, and the degree of increase was dependent on the severity of periodontitis (p<0.05). In contrast, the expression level of MPO was lower in the periodontal tissues of healthy controls than that in the periodontal tissues of periodontitis patients (p<0.05). SOD and HO are involved in oxidative stress via antioxidative activity, and MPO is involved in oxidative stress via peroxidative activity. Hence, these findings suggest that antioxidative activity depends on the severity of inflammation. In conclusion, SOD3, HO, and MPO may play a role in oxidative stress-induced periodontitis, and these three factors may be related to the severity of inflammation. These factors are expected to be applied to the diagnosis and treatment of periodontitis through more comprehensive studies.

UCI(KEPA)

간행물정보

  • : 의약학분야  > 기초치의학
  • : KCI등재
  • :
  • : 계간
  • : 2508-2558
  • : 2508-2566
  • : 학술지
  • : 연속간행물
  • : 1978-2021
  • : 1462


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45권3호(2021년 09월) 수록논문
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KCI등재

1Evaluation of superoxide dismutase 3, heme-oxygenase, and myeloperoxidase expression levels associated with oxidative stress in chronic periodontitis

저자 : Yong Yoon , Hyerin Kim , Jae Mok Lee

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 99-106 (8 pages)

다운로드

(기관인증 필요)

초록보기

This study aimed to investigate the expression levels of antioxidative enzymes such as superoxide dismutase 3 (SOD3), heme-oxygenase (HO), and myeloperoxidase (MPOs), which are known to be associated with oxidative stress induction in chronic inflammatory conditions like periodontitis. We compared the expression levels of SOD3, HO, and MPO in the periodontal tissues of healthy individuals with those in the periodontal tissues of chronic periodontitis patients. The expression levels of SOD3, HO, and MPO were determined by Western blot technique, and the data were statistically analyzed. The expression levels of SOD3 and HO increased in periodontitis patients compared with those in healthy controls, and the degree of increase was dependent on the severity of periodontitis (p<0.05). In contrast, the expression level of MPO was lower in the periodontal tissues of healthy controls than that in the periodontal tissues of periodontitis patients (p<0.05). SOD and HO are involved in oxidative stress via antioxidative activity, and MPO is involved in oxidative stress via peroxidative activity. Hence, these findings suggest that antioxidative activity depends on the severity of inflammation. In conclusion, SOD3, HO, and MPO may play a role in oxidative stress-induced periodontitis, and these three factors may be related to the severity of inflammation. These factors are expected to be applied to the diagnosis and treatment of periodontitis through more comprehensive studies.

KCI등재

2Nasal packing with bupivacaine during nasotracheal intubation can reduce intubation-related epistaxis

저자 : Ho Kyung Yu , Jiyoung Park , Young-hoon Kang , Hee Bin Park , Sung Il Bae , Soo Hee Lee , Seong-ho Ok , Sang-ho Jeong , Miyeong Park

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 107-114 (8 pages)

다운로드

(기관인증 필요)

초록보기

Epistaxis often is caused by nasal mucosal damage and vascular injury after nasotracheal (NT) intubation. Bupivacaine constricts blood vessels at low concentrations and dilates them at high concentrations. In this study, in which we evaluated the effects of intranasal packing with bupivacaine to prevent epistaxis and pain induced by NT intubation, we classified 180 patients into three groups: an untreated group (n=60), a group pretreated with epinephrine (n=60), and a group pretreated with bupivacaine (n=60). In all groups, we used nasal Ring-Adair-Elwyn tubes with the thermosoftening method for NT intubation. We classified the degree of epistaxis as Grade 0 (none), Grade 1 (mild), Grade 2 (moderate), or Grade 3 (severe). We assessed postoperative visual analog scale (VAS) scores for nose pain in the recovery room. We found that the incidence of epistaxis in the group pretreated with bupivacaine was significantly less than was that of the untreated group (55% vs. 35%, p<0.05). Univariate logistic regression analysis revealed a reduction in epistaxis with bupivacaine nasal packing (odds ratio=0.689, 95% confidence interval=0.478, 0.992). Postoperative VAS scores after 30 minutes in the nasal area were lower in the group pretreated with bupivacaine than were those in the untreated group or the group pretreated with epinephrine (p<0.05). Therefore, we conclude that nasal packing with bupivacaine can help reduce epistaxis and nasal pain more effectively as compared to cases without pretreatment with this anesthetic.

KCI등재

3Comparison between the Rapid ID 32 Strep test system and 16S rRNA gene sequencing for the identification of α-hemolytic streptococci

저자 : Si Young Lee

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 115-118 (4 pages)

다운로드

(기관인증 필요)

초록보기

Oral viridans streptococcus is the most common bacterial species present in human dental plaque. The Rapid ID 32 Strep (bioMerieux, Marcy-l'Etoile, France) test system allows for the identification of most streptococci within 4 hours. The aim of this study was to evaluate the reliability of this test in identifying isolates of α-hemolytic oral streptococci in human dental plaque and compare it with that of the 16S rRNA sequencing method. A total of eighty-five α-hemolytic streptococcal isolates were identified using 16S rRNA gene sequencing and Rapid ID 32 Strep. The Rapid ID 32 Strep method correctly identified 80% of the species and 87% of the streptococcal groups but failed to accurately identify five isolates (three S. cristatus, one S. australis, and one S. tigurinus).

KCI등재

4Differences in the accuracy of potato dextrose agar and CHROMagar media in diagnosing oral candidiasis

저자 : Hyun-jeong Park , Ji Hoo Kim , Ji-won Ryu

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 119-124 (6 pages)

다운로드

(기관인증 필요)

초록보기

For the diagnosis of oral candidiasis, the most commonly used method is culturing the Candida strains acquired by rubbing the mucous membrane in the mouth using a sterile cotton swab on the medium. This study was conducted to compare the accuracy of Potato Dextrose Agar (PDA) and chromogenic CHROMagar media in diagnosing oral candidiasis. This study included patients diagnosed with oral candidiasis who visited Chosun University Dental Hospital between January 1, 2018 and February 28, 2019. All study subjects were tested using the culture method to diagnose oral candidiasis. For statistical analysis of this study, IBM SPSS version 25.0 (IBM Co., Armonk, NY, USA) was used. Cross analysis was used to compare the diagnostic accuracy of PDA and CHROMagar media as well as treatment effects and diagnoses using each medium. When diagnosed using PDA medium, the sensitivity was high at 91.3% but the specificity was relatively low at 46.0%. It was observed that the accuracy of the diagnosis method using PDA medium was relatively lower than that of the diagnosis method using CHROMagar medium. But the treatment effects in groups diagnosed with PDA medium were higher than those diagnosed with CHROMaga medium. According to the results of our study, CHROMagar medium is recommended for the diagnosis of oral candidiasis; as an alternative, a nonselective medium, such as PDA medium, can be used for the diagnosis of oral candidiasis.

KCI등재

5Image findings of filler-related radiopacities and multiple miliary osteoma in facial region

저자 : Young-eun Kwon , Seo-young An

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 125-134 (10 pages)

다운로드

(기관인증 필요)

초록보기

The identification of radiopacities in the facial region is important during routine radiographic examination. This study analyzed the radiographic findings of filler-related radiopacities (FRR) and multiple miliary osteomas (MMO) in this region using dental radiographs. Image data were obtained from patients at the Kyungpook National University Dental Hospital. Cone-beam computed tomography (CBCT)/CT data of patients with multiple facial radiopacities on plain images (panoramic and periapical images; 16 FRR and 224 MMO) were collected and matched with the corresponding conventional images. In the CBCT/CT images, the FRRs were mainly observed in the cheek (87.5%) and retromaxillary space (68.8%) whereas the MMOs were mostly located in the superficial areas of the cheek (81.3%) and chin (36.2%). The statistical differences were only in the retromaxillary space (p<0.05). The FRRs were mostly ring-shaped (68.8%) or nodular in appearance (56.3%), whereas the MMOs presented as calcific foci (96.4%). The results of the chi-square test revealed statistically significant differences in the detection of FRRs and MMOs in the panoramic images (p<0.05), but not the periapical images. The FRRs were located in the deeper layers of the skin and were more diverse in appearance than the MMOs. Moreover, FRRs were better identified than MMO in the panoramic images. Dentists should have knowledges about image findings of FRRs and be able to differentiate them from MMOs based on the radiographic images.

KCI등재

6Awareness of national health insurance-covered dental care of adults in Jeju province

저자 : Soobin Lee , Sung-joon Kim , Chan-woo Jo , Jaeman Woo

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 135-142 (8 pages)

다운로드

(기관인증 필요)

초록보기

Advancements in medical care resulted in increase of average longevity. In turn, people have become more concerned about health, oral health, and quality of life. Such change has led to need for systematic and prevention-oriented healthcare service. This study aimed to provide preliminary information on the level of familiarity with national health insurance (NHI) benefits by the general public in order to help make decisions regarding education and advertisement policies. 337 adults who visited Korea Association of Health Promotion health examination center in Jeju were given self-administered surveys regarding personal oral health status, familiarity with NHI-covered procedures, and personal interest in oral health, and the results were analyzed statistically. 83.4% answered 'Yes,' to awareness of NHI coverage of dental scaling. Most people answered 'Yes' to awareness of the fact that NHI-covered dental scaling begins at 19 years of age, while relatively few people were familiar with NHI-covered denture and dental implant procedures. According to this study, many respondents were still not familiar with the expanded NHI coverage. Especially the younger population lacked information on NHI-covered denture and dental implant, indicating need for public education and advertisements. In order to efficiently advertise and educate, joint effort by the government and medical facilities is recommended. Utilization of social media in addition to the more traditional mass media should be effective in conveying information to the younger population. Age-appropriate education for policy change and coverage expansion regarding NHI-covered denture and dental implant is also advised.

KCI등재

7Correction of facial asymmetry using a patient-specific three-dimensional printed polycarprolactone/beta tricalcium phosphate scaffold: a case report

저자 : Min-keun Kim , Jin-woo Han , Kwang-jun Kwon , Young-wook Park , Jin-hyung Shim

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 143-149 (7 pages)

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Facial asymmetry is difficult to correct mainly because of the large volume of implant required for reconstruction, which is hard to estimate. Computer-aided surgical planning using three-dimensional (3D)-printed implants is developing rapidly, with promising clinical results being reported in reconstructive, orthognathic, and other surgical fields. A 54-year-old male patient presented with facial asymmetry caused by fibular free flap displacement. This was surgically corrected using a customized, 3D-printed polycarprolactone/beta tricalcium phosphate scaffold. The implant fit well and was easily fixed to the right mandibular angle area, resulting in an improvement in the facial contour of the patient. Throughout the follow-up period, the PCL/β-TCP implant was detected using an ultrasonic device and remained without volumetric change. There was also no wound dehiscence or implant displacement. Thus, a patient-specific 3D-printed biodegradable scaffold can effectively facilitate surgical correction of facial asymmetry. However, facial contour sequelae, stability, and resorption must be assessed over a long-term follow-up period.

KCI등재

8Clinical, histological, and deep learning-based assessments and treatment of oral verruciform xanthoma: a case report

저자 : Jae-hong Lee , Seong-nyum Jeong

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 150-155 (6 pages)

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Verruciform xanthoma is a benign growth found on the oral mucosa. Clinically, verruciform xanthoma is an asymptomatic lesion, and depending on the amount of keratin present on the surface of the oral mucosa, it can appear as a reddish-gray papillary, flat lesion or a slightly raised, rough lesion. The verrucous structure and exophytic properties of these lesions are similar to those of malignant tumors; therefore, histopathological assessment is required for an accurate and definitive diagnosis. The purpose of this case report is to present the clinical, histological, and deep learning-based assessments and treatment of verruciform xanthoma of the maxillary palatal gingiva.

KCI등재

9Posterior dental implant prosthesis fabrication using double scanning technique: a case report

저자 : Jung Woo , Hyun-jun Park , Hee-jung Kim , Joo-hun Song

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 156-163 (8 pages)

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The disadvantages of the traditional approach for fabricating dental implant prostheses have been addressed via oral scanning and the use of computer-aided design/computer-aided manufacturing systems. The use of an intraoral scanner can eliminate the need for impression materials and impression trays, which are inconvenient for patients, particularly those with limited mouth opening or an overly sensitive gag reflex. Moreover, it can reduce the additional costs of fabricating, storing, and handling the patients' models. This case report describes the fabrication of a posterior implant prosthesis using double scanning technique, which produced satisfactory results both esthetically and functionally. The double scanning technique produces a more accurate image of the target region by overlapping data from both intraoral and extraoral scans. Therefore, it can address the disadvantages of both traditional and digital impressions, reduce patient discomfort, and decrease the incidence of remakes, which can arise due to potential errors during the fabrication process.

1
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KCI등재

1Evaluation of superoxide dismutase 3, heme-oxygenase, and myeloperoxidase expression levels associated with oxidative stress in chronic periodontitis

저자 : Yong Yoon , Hyerin Kim , Jae Mok Lee

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 99-106 (8 pages)

다운로드

(기관인증 필요)

초록보기

This study aimed to investigate the expression levels of antioxidative enzymes such as superoxide dismutase 3 (SOD3), heme-oxygenase (HO), and myeloperoxidase (MPOs), which are known to be associated with oxidative stress induction in chronic inflammatory conditions like periodontitis. We compared the expression levels of SOD3, HO, and MPO in the periodontal tissues of healthy individuals with those in the periodontal tissues of chronic periodontitis patients. The expression levels of SOD3, HO, and MPO were determined by Western blot technique, and the data were statistically analyzed. The expression levels of SOD3 and HO increased in periodontitis patients compared with those in healthy controls, and the degree of increase was dependent on the severity of periodontitis (p<0.05). In contrast, the expression level of MPO was lower in the periodontal tissues of healthy controls than that in the periodontal tissues of periodontitis patients (p<0.05). SOD and HO are involved in oxidative stress via antioxidative activity, and MPO is involved in oxidative stress via peroxidative activity. Hence, these findings suggest that antioxidative activity depends on the severity of inflammation. In conclusion, SOD3, HO, and MPO may play a role in oxidative stress-induced periodontitis, and these three factors may be related to the severity of inflammation. These factors are expected to be applied to the diagnosis and treatment of periodontitis through more comprehensive studies.

KCI등재

2Nasal packing with bupivacaine during nasotracheal intubation can reduce intubation-related epistaxis

저자 : Ho Kyung Yu , Jiyoung Park , Young-hoon Kang , Hee Bin Park , Sung Il Bae , Soo Hee Lee , Seong-ho Ok , Sang-ho Jeong , Miyeong Park

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 107-114 (8 pages)

다운로드

(기관인증 필요)

초록보기

Epistaxis often is caused by nasal mucosal damage and vascular injury after nasotracheal (NT) intubation. Bupivacaine constricts blood vessels at low concentrations and dilates them at high concentrations. In this study, in which we evaluated the effects of intranasal packing with bupivacaine to prevent epistaxis and pain induced by NT intubation, we classified 180 patients into three groups: an untreated group (n=60), a group pretreated with epinephrine (n=60), and a group pretreated with bupivacaine (n=60). In all groups, we used nasal Ring-Adair-Elwyn tubes with the thermosoftening method for NT intubation. We classified the degree of epistaxis as Grade 0 (none), Grade 1 (mild), Grade 2 (moderate), or Grade 3 (severe). We assessed postoperative visual analog scale (VAS) scores for nose pain in the recovery room. We found that the incidence of epistaxis in the group pretreated with bupivacaine was significantly less than was that of the untreated group (55% vs. 35%, p<0.05). Univariate logistic regression analysis revealed a reduction in epistaxis with bupivacaine nasal packing (odds ratio=0.689, 95% confidence interval=0.478, 0.992). Postoperative VAS scores after 30 minutes in the nasal area were lower in the group pretreated with bupivacaine than were those in the untreated group or the group pretreated with epinephrine (p<0.05). Therefore, we conclude that nasal packing with bupivacaine can help reduce epistaxis and nasal pain more effectively as compared to cases without pretreatment with this anesthetic.

KCI등재

3Comparison between the Rapid ID 32 Strep test system and 16S rRNA gene sequencing for the identification of α-hemolytic streptococci

저자 : Si Young Lee

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 115-118 (4 pages)

다운로드

(기관인증 필요)

초록보기

Oral viridans streptococcus is the most common bacterial species present in human dental plaque. The Rapid ID 32 Strep (bioMerieux, Marcy-l'Etoile, France) test system allows for the identification of most streptococci within 4 hours. The aim of this study was to evaluate the reliability of this test in identifying isolates of α-hemolytic oral streptococci in human dental plaque and compare it with that of the 16S rRNA sequencing method. A total of eighty-five α-hemolytic streptococcal isolates were identified using 16S rRNA gene sequencing and Rapid ID 32 Strep. The Rapid ID 32 Strep method correctly identified 80% of the species and 87% of the streptococcal groups but failed to accurately identify five isolates (three S. cristatus, one S. australis, and one S. tigurinus).

KCI등재

4Differences in the accuracy of potato dextrose agar and CHROMagar media in diagnosing oral candidiasis

저자 : Hyun-jeong Park , Ji Hoo Kim , Ji-won Ryu

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 119-124 (6 pages)

다운로드

(기관인증 필요)

초록보기

For the diagnosis of oral candidiasis, the most commonly used method is culturing the Candida strains acquired by rubbing the mucous membrane in the mouth using a sterile cotton swab on the medium. This study was conducted to compare the accuracy of Potato Dextrose Agar (PDA) and chromogenic CHROMagar media in diagnosing oral candidiasis. This study included patients diagnosed with oral candidiasis who visited Chosun University Dental Hospital between January 1, 2018 and February 28, 2019. All study subjects were tested using the culture method to diagnose oral candidiasis. For statistical analysis of this study, IBM SPSS version 25.0 (IBM Co., Armonk, NY, USA) was used. Cross analysis was used to compare the diagnostic accuracy of PDA and CHROMagar media as well as treatment effects and diagnoses using each medium. When diagnosed using PDA medium, the sensitivity was high at 91.3% but the specificity was relatively low at 46.0%. It was observed that the accuracy of the diagnosis method using PDA medium was relatively lower than that of the diagnosis method using CHROMagar medium. But the treatment effects in groups diagnosed with PDA medium were higher than those diagnosed with CHROMaga medium. According to the results of our study, CHROMagar medium is recommended for the diagnosis of oral candidiasis; as an alternative, a nonselective medium, such as PDA medium, can be used for the diagnosis of oral candidiasis.

KCI등재

5Image findings of filler-related radiopacities and multiple miliary osteoma in facial region

저자 : Young-eun Kwon , Seo-young An

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 125-134 (10 pages)

다운로드

(기관인증 필요)

초록보기

The identification of radiopacities in the facial region is important during routine radiographic examination. This study analyzed the radiographic findings of filler-related radiopacities (FRR) and multiple miliary osteomas (MMO) in this region using dental radiographs. Image data were obtained from patients at the Kyungpook National University Dental Hospital. Cone-beam computed tomography (CBCT)/CT data of patients with multiple facial radiopacities on plain images (panoramic and periapical images; 16 FRR and 224 MMO) were collected and matched with the corresponding conventional images. In the CBCT/CT images, the FRRs were mainly observed in the cheek (87.5%) and retromaxillary space (68.8%) whereas the MMOs were mostly located in the superficial areas of the cheek (81.3%) and chin (36.2%). The statistical differences were only in the retromaxillary space (p<0.05). The FRRs were mostly ring-shaped (68.8%) or nodular in appearance (56.3%), whereas the MMOs presented as calcific foci (96.4%). The results of the chi-square test revealed statistically significant differences in the detection of FRRs and MMOs in the panoramic images (p<0.05), but not the periapical images. The FRRs were located in the deeper layers of the skin and were more diverse in appearance than the MMOs. Moreover, FRRs were better identified than MMO in the panoramic images. Dentists should have knowledges about image findings of FRRs and be able to differentiate them from MMOs based on the radiographic images.

KCI등재

6Awareness of national health insurance-covered dental care of adults in Jeju province

저자 : Soobin Lee , Sung-joon Kim , Chan-woo Jo , Jaeman Woo

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 135-142 (8 pages)

다운로드

(기관인증 필요)

초록보기

Advancements in medical care resulted in increase of average longevity. In turn, people have become more concerned about health, oral health, and quality of life. Such change has led to need for systematic and prevention-oriented healthcare service. This study aimed to provide preliminary information on the level of familiarity with national health insurance (NHI) benefits by the general public in order to help make decisions regarding education and advertisement policies. 337 adults who visited Korea Association of Health Promotion health examination center in Jeju were given self-administered surveys regarding personal oral health status, familiarity with NHI-covered procedures, and personal interest in oral health, and the results were analyzed statistically. 83.4% answered 'Yes,' to awareness of NHI coverage of dental scaling. Most people answered 'Yes' to awareness of the fact that NHI-covered dental scaling begins at 19 years of age, while relatively few people were familiar with NHI-covered denture and dental implant procedures. According to this study, many respondents were still not familiar with the expanded NHI coverage. Especially the younger population lacked information on NHI-covered denture and dental implant, indicating need for public education and advertisements. In order to efficiently advertise and educate, joint effort by the government and medical facilities is recommended. Utilization of social media in addition to the more traditional mass media should be effective in conveying information to the younger population. Age-appropriate education for policy change and coverage expansion regarding NHI-covered denture and dental implant is also advised.

KCI등재

7Correction of facial asymmetry using a patient-specific three-dimensional printed polycarprolactone/beta tricalcium phosphate scaffold: a case report

저자 : Min-keun Kim , Jin-woo Han , Kwang-jun Kwon , Young-wook Park , Jin-hyung Shim

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 143-149 (7 pages)

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Facial asymmetry is difficult to correct mainly because of the large volume of implant required for reconstruction, which is hard to estimate. Computer-aided surgical planning using three-dimensional (3D)-printed implants is developing rapidly, with promising clinical results being reported in reconstructive, orthognathic, and other surgical fields. A 54-year-old male patient presented with facial asymmetry caused by fibular free flap displacement. This was surgically corrected using a customized, 3D-printed polycarprolactone/beta tricalcium phosphate scaffold. The implant fit well and was easily fixed to the right mandibular angle area, resulting in an improvement in the facial contour of the patient. Throughout the follow-up period, the PCL/β-TCP implant was detected using an ultrasonic device and remained without volumetric change. There was also no wound dehiscence or implant displacement. Thus, a patient-specific 3D-printed biodegradable scaffold can effectively facilitate surgical correction of facial asymmetry. However, facial contour sequelae, stability, and resorption must be assessed over a long-term follow-up period.

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8Clinical, histological, and deep learning-based assessments and treatment of oral verruciform xanthoma: a case report

저자 : Jae-hong Lee , Seong-nyum Jeong

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 150-155 (6 pages)

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Verruciform xanthoma is a benign growth found on the oral mucosa. Clinically, verruciform xanthoma is an asymptomatic lesion, and depending on the amount of keratin present on the surface of the oral mucosa, it can appear as a reddish-gray papillary, flat lesion or a slightly raised, rough lesion. The verrucous structure and exophytic properties of these lesions are similar to those of malignant tumors; therefore, histopathological assessment is required for an accurate and definitive diagnosis. The purpose of this case report is to present the clinical, histological, and deep learning-based assessments and treatment of verruciform xanthoma of the maxillary palatal gingiva.

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9Posterior dental implant prosthesis fabrication using double scanning technique: a case report

저자 : Jung Woo , Hyun-jun Park , Hee-jung Kim , Joo-hun Song

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 156-163 (8 pages)

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The disadvantages of the traditional approach for fabricating dental implant prostheses have been addressed via oral scanning and the use of computer-aided design/computer-aided manufacturing systems. The use of an intraoral scanner can eliminate the need for impression materials and impression trays, which are inconvenient for patients, particularly those with limited mouth opening or an overly sensitive gag reflex. Moreover, it can reduce the additional costs of fabricating, storing, and handling the patients' models. This case report describes the fabrication of a posterior implant prosthesis using double scanning technique, which produced satisfactory results both esthetically and functionally. The double scanning technique produces a more accurate image of the target region by overlapping data from both intraoral and extraoral scans. Therefore, it can address the disadvantages of both traditional and digital impressions, reduce patient discomfort, and decrease the incidence of remakes, which can arise due to potential errors during the fabrication process.

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