논문 상세보기

대한피부과학회> 대한피부과학회지> 비전형적 피부섬유종의 임상적 특징과 더모스코피 소견에 관한 연구

KCI등재SCOUPUS

비전형적 피부섬유종의 임상적 특징과 더모스코피 소견에 관한 연구

Clinico-Dermoscopic Features of Atypical Dermatofibroma

오하늘 ( Haneul Oh ) , 문혜림 ( Hye-rim Moon ) , 유화정 ( Hwa-jung Ryu ) , 김일환 ( Il-hwan Kim )
  • : 대한피부과학회
  • : 대한피부과학회지 59권5호
  • : 연속간행물
  • : 2021년 06월
  • : 341-347(7pages)
대한피부과학회지

DOI


목차

서 론
대상 및 방법
결 과
고 찰
결 론
CONFLICTS OF INTEREST
ORCID
REFERENCES

키워드 보기


초록 보기

Background: Dermatofibroma is a common benign skin neoplasm that is usually easy to recognize; however, in some cases, it is difficult to differentiate it from atypical dermatofibroma. Atypical dermatofibroma is a rare variant of a more aggressive nature and requires complete excision due to its tendency to recur.
Objective: To describe the clinical and dermoscopic features of dermatofibromas with special emphasis on the characteristics of atypical subtypes and to differentiate them from typical subtypes on the basis of results.
Methods: We retrospectively searched the databases of patients of Korea University Ansan Hospital from January 2010 to December 2019 who underwent skin biopsies or excision surgeries and had pathological reports of dermatofibroma. Analyses of the clinical characteristics (age, sex, number of lesions, anatomical site) and dermoscopic patterns were performed.
Results: Dermoscopic patterns were analyzed in 148 cases of dermatofibroma; peripheral delicate pigment networks and central white scar-like patches were the most common patterns found in 45 cases (30.4%). In eight cases of atypical dermatofibroma, three cases (37.5%) showed peripheral homogenous areas and central white networks, followed by multiple white scar-like patches in 2 cases (25.0%), peripheral delicate pigment networks, and central white scar-like patches in 2 cases (25.0%). Dermoscopy revealed a statistically significant difference in the peripheral homogenous area and the central white network pattern between the two groups.
Conclusion: In this study, we analyzed the dermoscopic findings of 148 patients with dermatofibroma and found that the peripheral homogenous area and central white network patterns were significantly more in atypical dermatofibroma. (Korean J Dermatol 2021;59(5):341∼347)

UCI(KEPA)

간행물정보

  • : 의약학분야  > 피부과학
  • : KCI등재
  • : SCOPUS
  • : 월간
  • : 0494-4739
  • : 2713-7627
  • : 학술지
  • : 연속간행물
  • : 1960-2021
  • : 9544


저작권 안내

한국학술정보㈜의 모든 학술 자료는 각 학회 및 기관과 저작권 계약을 통해 제공하고 있습니다.

이에 본 자료를 상업적 이용, 무단 배포 등 불법적으로 이용할 시에는 저작권법 및 관계법령에 따른 책임을 질 수 있습니다.

59권5호(2021년 06월) 수록논문
최근 권호 논문
| | | |

KCI등재 SCOPUS

1한국인 건선 환자의 경제적 비용 부담

저자 : 한별 ( Byeol Han ) , 정기헌 ( Ki-heon Jeong ) , 김태균 ( Tae-gyun Kim ) , 김광중 ( Kwang Joong Kim ) , 김동현 ( Dong Hyun Kim ) , 김병수 ( Byung-soo Kim ) , 박경덕 ( Kyung Duck Park ) , 박철종 ( Chul Jong Park ) , 박혜진 ( Hai-jin Park ) , 방철환 ( Chul Hwan Bang ) , 신봉석 ( Bong Seok S

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 321-331 (11 pages)

다운로드

(기관인증 필요)

초록보기

Background: Psoriasis is a chronic disease that can have accompanying comorbidities including arthritis, metabolic syndrome, and cardiovascular diseases. Patients with psoriasis tend to frequently visit medical institutions, and their economic burden for medical services is high.
Objective: To investigate the economic burden of psoriasis in Korea.
Methods: The Korean Society for Psoriasis conducted a multi-center field survey of the patients and analyzed the national insurance claim data. Also, we discussed the medical environment of psoriasis in Korea based on the results.
Results: The economic burden of psoriasis patients is substantial and varied by the type of medical institute. Patients also paid the indirect and intangible medical costs. Biological agents, which is used in patients with severe psoriasis, led to an increase in the cost.
Conclusion: This is the first study to estimate the economic burden of psoriasis in Korea comprehensively. To improve the medical environment of psoriasis and alleviate the burden of patients, discussion on the more efficient health policy and medical insurance criteria for psoriasis would be needed. (Korean J Dermatol 2021;59(5):321∼ 331)

KCI등재 SCOPUS

2신생아 집중치료실 환아에서 유아혈관종의 위험인자 분석

저자 : 오재홍 ( Jae Hong Oh ) , 김병윤 ( Byung Yoon Kim ) , 최미라 ( Mira Choi )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 332-340 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background: Infantile hemangioma (IH) is one of the most common tumors in infants. IH occurs more commonly in premature and low birth weight infants, but only a few studies have analyzed the risk factors for IH in neonatal intensive care units (NICUs) in Korea.
Objective: We investigated the risk factors for IH in patients admitted to the NICU at a single institution.
Methods: A single-center retrospective case-control study was conducted in 37 patients with hemangioma and 185 matched-control babies who were admitted to the NICU between 2013 and 2020. Odds ratios (ORs) and multivariate conditional logistic regression models were used to determine the associations between IH and the potential risk factors.
Results: Of the 1,206 neonates admitted to the NICU, 37 had IH, and the prevalence was 3.1%. IH was most commonly found on the trunk (33.3%), followed by the head and neck (29.4%). After adjustment, the risk factors found to be significantly associated with IH were female sex (OR=3.0, 95% confidence interval [CI]=1.4∼6.8), extreme preterm (OR=6.9, 95% CI=1.3∼38.0), very low birth weight (OR=11.9, 95% CI=2.9∼49.3), low 1-minute Apgar scores of <7 (OR=2.3, 95% CI=1.1∼4.9), and multiple gestation (OR=5.0, 95% CI=1.7∼14.9).
Conclusion: This matched case-control study revealed that risk factors such as female sex, extremely preterm birth, very low birth weight, low 1-minute Apgar score, and multiple gestations may affect the occurrence of IH. Therefore, if these risk factors are present, they need to be actively managed at an early stage through close physical examination to prevent complications. (Korean J Dermatol 2021;59(5):332∼340)

KCI등재 SCOPUS

3비전형적 피부섬유종의 임상적 특징과 더모스코피 소견에 관한 연구

저자 : 오하늘 ( Haneul Oh ) , 문혜림 ( Hye-rim Moon ) , 유화정 ( Hwa-jung Ryu ) , 김일환 ( Il-hwan Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 341-347 (7 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기

Background: Dermatofibroma is a common benign skin neoplasm that is usually easy to recognize; however, in some cases, it is difficult to differentiate it from atypical dermatofibroma. Atypical dermatofibroma is a rare variant of a more aggressive nature and requires complete excision due to its tendency to recur.
Objective: To describe the clinical and dermoscopic features of dermatofibromas with special emphasis on the characteristics of atypical subtypes and to differentiate them from typical subtypes on the basis of results.
Methods: We retrospectively searched the databases of patients of Korea University Ansan Hospital from January 2010 to December 2019 who underwent skin biopsies or excision surgeries and had pathological reports of dermatofibroma. Analyses of the clinical characteristics (age, sex, number of lesions, anatomical site) and dermoscopic patterns were performed.
Results: Dermoscopic patterns were analyzed in 148 cases of dermatofibroma; peripheral delicate pigment networks and central white scar-like patches were the most common patterns found in 45 cases (30.4%). In eight cases of atypical dermatofibroma, three cases (37.5%) showed peripheral homogenous areas and central white networks, followed by multiple white scar-like patches in 2 cases (25.0%), peripheral delicate pigment networks, and central white scar-like patches in 2 cases (25.0%). Dermoscopy revealed a statistically significant difference in the peripheral homogenous area and the central white network pattern between the two groups.
Conclusion: In this study, we analyzed the dermoscopic findings of 148 patients with dermatofibroma and found that the peripheral homogenous area and central white network patterns were significantly more in atypical dermatofibroma. (Korean J Dermatol 2021;59(5):341∼347)

KCI등재 SCOPUS

4세균에 의한 피부 감염증에서 항생제 감수성과 임상적 특징에 관한 연구

저자 : 이재호 ( Jae-ho Lee ) , 이수경 ( Soo-kyung Lee ) , 김명신 ( Myoung-shin Kim ) , 이운하 ( Un-ha Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 348-362 (15 pages)

다운로드

(기관인증 필요)

초록보기

Background: Bacterial skin soft-tissue infection is a common clinical manifestation in dermatology. The treatment of bacterial skin infections is often challenging due to antibiotic resistance, including methicillin resistance.
Objective: The aim of this study was to investigate the isolation rate of bacteria, antibiotic susceptibility, clinical features, and factors associated with treatment response in bacterial skin infections.
Methods: We retrospectively reviewed the medical records of patients who underwent ordinary bacterial skin cultures of the site of superficial skin infections between 2010 and 2019.
Results: A total of 1,298 patients were included in the study. The most commonly isolated bacteria were Staphylococcus aureus (31.3%), followed by coagulase-negative staphylococci (22.0%) and Pseudomonas species (4.2%). The methicillin-resistance rate of S. aureus was 22.7%. Crusted lesions (p=0.025), treatment with steroids (p=0.035), duration over 7 days (p=0.009), and isolation of Pseudomonas (p<0.001) or other uncommon species (non-Staphylococcus, Streptococcus, and Pseudomonas species, p<0.001) were significantly associated with treatment response.
Conclusion: The methicillin-resistance rate of S. aureus was similar to that of the past 5 years, but the mupirocin-resistance rate significantly increased. Lesions with crust or those that were treated with steroids showed good treatment responses, but longer disease durations of over 7 days and skin infections caused by Pseudomonas or other uncommon species were poor prognostic factors that should receive more attention. (Korean J Dermatol 2021;59(5):348∼362)

KCI등재 SCOPUS

5색소접촉피부염의 임상적 고찰 및 위험인자: 색소접촉피부염과 알레르기접촉피부염의 비교 분석

저자 : 김현빈 ( Hyeon Bin Kim ) , 윤숙정 ( Sook Jung Yun ) , 이승철 ( Seung-chul Lee ) , 이지범 ( Jee-bum Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 363-369 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: Pigmented contact dermatitis (PCD) is a non-eczematous contact dermatitis characterized by hyperpigmentation with few or no signs of dermatitis. The pathomechanism of PCD is still unknown; there are few case reports of PCD caused by hair dye, henna, and cosmetics.
Objective: This study aimed to analyze the clinical features and the significance of risk factors in adult Korean patients with PCD.
Methods: We retrospectively reviewed 75 patients with PCD. Clinical features including age, sex, duration, location, and risk factors were obtained from electronic medical records. To determine the significance of the risk factors of PCD, we compared these patients with 155 patients diagnosed with allergic contact dermatitis (ACD) without hyperpigmentation.
Results: The mean age of onset of PCD in patients was 55.5 years, and the male:female ratio was 1:14. The mean duration of PCD was 16.3 months. The number of patients with PCD who had histories of hair dye use (n=67, 89.3%) and health supplement consumption (n=18, 24.0%) was significantly higher than that of patients with ACD. There were no significant differences in medication, cosmetic changes, stress history, results of patch test, patch testing with the patient's own products, immunoglobulin E (kU/L), and eosinophils (cells/μL).
Conclusion: This study analyzed the clinical features and risk factors of PCD and ACD in adult Korean patients, and it suggests that PCD may be caused by irritation induced by variable factors and not allergic reactions. (Korean J Dermatol 2021;59(5):363∼369)

KCI등재 SCOPUS

6어루러기에서 경구 아졸계 항진균제의 치료 효과 비교: 체계적 문헌고찰 및 메타분석

저자 : 권륭 ( Ryung Kwon ) , 이설희 ( Sul Hee Lee ) , 박영립 ( Young Lip Park ) , 이상훈 ( Sang Hoon Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 370-378 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background: In pityriasis versicolor, systemic antifungal agents may be indicated for widespread or refractory lesions rather than topical treatment. Oral ketoconazole is an effective treatment for pityriasis versicolor. To our knowledge, this is the first meta-analysis to compare antifungal agents one-to-one.
Objective: To compare the effectiveness of oral azole antifungal agents (fluconazole, itraconazole, and ketoconazole) one-to-one in pityriasis versicolor.
Methods: A computerized search was performed in different databases, including PubMed, Cochrane, EMBASE, OVID Medline, KoreaMed, KISS, and MedRIC. Seven randomized controlled trials were included. Further, statistical analyses of the extracted outcome data from the studies were performed using Rex Software (ver. 3.0.1).
Results: A total of 1,828 records were identified. The results of the meta-analysis including seven studies revealed no significant differences in the mycological cure rates between fluconazole and ketoconazole (risk ratio [RR]: 1.01, 95% confidence interval [CI]: 0.93∼1.09, p=0.8246), fluconazole and itraconazole (RR: 1.14, 95% CI: 0.81∼1.60, p=0.4512), and ketoconazole and itraconazole (RR: 1.07, 95% CI: 0.96∼1.20, p=0.2265).
Conclusion: There was no superiority in the therapeutic effect of any drug among the oral azole antifungals used in pityriasis versicolor. (Korean J Dermatol 2021;59(5):370∼378)

KCI등재 SCOPUS

7만성광선피부염 환자에서 유병기간, 첩포검사 및 광첩포검사 결과와 최소홍반량 값과 임상적 중등도와의 상관관계

저자 : 김정환 ( Jung-hwan Kim ) , 김기호 ( Ki-ho Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 379-388 (10 pages)

다운로드

(기관인증 필요)

초록보기

Background: Chronic actinic dermatitis (CAD) is an uncommon eczematous photosensitivity disorder having a well-known relationship with allergic or photoallergic contact dermatitis. Moreover, the prognosis of CAD is worse in patients with lower minimal erythema doses (MEDs). However, the correlations between disease duration, contact and photocontact allergens, and MED values in CAD have not been reported.
Objective: To investigate the correlations among MED values, disease duration, and allergic patch/photopatch testing results and to elucidate the correlation between clinical severity and contact/photocontact allergens.
Methods: This study included 121 patients with CAD. Clinical data were analyzed according to the MED values, disease durations, and contact/photocontact allergens. Phototesting and patch/photopatch testing was performed in all the patients.
Results: The MED value was inversely correlated with disease duration for both MED-ultraviolet A and MED-ultraviolet B, with lower MED values for higher numbers of positive items in the patch/photopatch test. The most frequently detected allergens in the patch and photopatch tests were p-phenylenediamine (n=36, 9.3%) and Balsam of Peru (n=29, 21.3%). Clinically, patients demonstrating a greater number of detected allergens show poorer clinical severities (p<0.05).
Conclusion: The number of contact/photocontact allergens correlates with the severity of CAD. (Korean J Dermatol 2021;59(5):379∼388)

KCI등재 SCOPUS

8Reinfection Rate of Cutaneous Warts in Korea: A Nationwide Cross-Sectional Population-Based Study

저자 : Yeong Ho Kim , Kyungdo Han , Chul Hwan Bang , Ji Hyun Lee , Jun Young Lee , Yong Gyu Park , Young Min Park

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 389-393 (5 pages)

다운로드

(기관인증 필요)

초록보기

Background: Cutaneous warts tend to recur despite of various treatment modalities. However, previous studies provided few data on their reinfection rate.
Objective: In this study, we investigated the reinfection rate along with the incidence and prevalence rates of cutaneous warts.
Methods: We conducted a nationwide, cross-sectional population-based study using the Korean National Health Insurance Service database from January 2006 through December 2016. Patients who visited outpatient clinics with an International Classification of Disease-10 code of viral warts (B07) were included. The reinfection rate was calculated as a percentage of patients with an initial visit in 2010 and subsequent visits for cutaneous warts with at least a six-month interval from last visit until 2016.
Results: From 2006 to 2016, the overall incidence and prevalence rates of cutaneous warts increased from 2.99 to 7.69 per 1,000 population and from 3.45 to 10.94 per 1,000 population, respectively. The overall reinfection rate of cutaneous warts was 30.9%. The reinfection rate of males and females was 31.6% and 30.0%, respectively. Children under ten years old had the highest reinfection rate (34.3%).
Conclusion: These results demonstrate that the reinfection rate of cutaneous warts is the highest in male children under ten years old. Therefore, these patients should be monitored closely after treatment. (Korean J Dermatol 2021;59(5):389∼393)

KCI등재 SCOPUS

9Pustular Eruption Induced by Adalimumab in a Patient with Ankylosing Spondylitis: A Case Report

저자 : Ji-hoon Lim , Soon-hyo Kwon , Woo-young Sim , Bark-lynn Lew

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 394-397 (4 pages)

다운로드

(기관인증 필요)

초록보기

Many cutaneous adverse reactions including eczematoid dermatitis and lichenoid eruption have been reported with the increased usage of tumor necrosis factor-α inhibitors. However, there are very few reports of generalized pustular eruptions with adalimumab administration. A 44-year-old woman visited our clinic with multiple skin lesions scattered across her body. The patient developed these lesions three days after the initiation of adalimumab treatment. At the time of the patient's visit, physical examination revealed multiple erythematous papules and pustules across the body. Histopathological findings revealed subcorneal neutrophilic microabscess formation with dense perivascular and perifollicular infiltration that was mainly composed of lymphocytes and neutrophils. We diagnosed the patient with cutaneous pustular eruptions due to adalimumab exposure and initiated treatment with prednisolone and discontinued adalimumab injections. After 1 month of treatment, the patient's skin lesions improved. Herein, we report a case of generalized pustular eruptions, a rare cutaneous adverse reaction to adalimumab. (Korean J Dermatol 2021;59(5):394∼397)

KCI등재 SCOPUS

10A Case of Alopecia Areata in a Patient with Type I Pityriasis Rubra Pilaris

저자 : Dong Geon Lee , Hoon Kang , Jung Eun Kim

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 398-400 (3 pages)

다운로드

(기관인증 필요)

초록보기

There have been a few cases of alopecia areata (AA) patients with pityriasis rubra pilaris (PRP), but the relationship between them is unclear. To the best of our knowledge, there have been no cases of co-occurrence reported in Korea. A 58-year-old male presented with multiple erythematous follicular papules and scaly plaques on the both legs with diffuse keratotic thickening on both palms and soles for several months. After skin biopsy, he was diagnosed with type I PRP. After treatment with oral and topical steroid, vitamin D3 analogue, oral alitretinoin, and urea cream for one week, multiple, diffuse alopecic patches appeared. He was diagnosed with AA after skin biopsy and we added topical minoxidil. Herein, we report a case of AA in a patient with type I PRP. (Korean J Dermatol 2021;59(5):398∼400)

12
권호별 보기
같은 권호 다른 논문
| | | | 다운로드

KCI등재SCOUPUS

1한국인 건선 환자의 경제적 비용 부담

저자 : 한별 ( Byeol Han ) , 정기헌 ( Ki-heon Jeong ) , 김태균 ( Tae-gyun Kim ) , 김광중 ( Kwang Joong Kim ) , 김동현 ( Dong Hyun Kim ) , 김병수 ( Byung-soo Kim ) , 박경덕 ( Kyung Duck Park ) , 박철종 ( Chul Jong Park ) , 박혜진 ( Hai-jin Park ) , 방철환 ( Chul Hwan Bang ) , 신봉석 ( Bong Seok S

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 321-331 (11 pages)

다운로드

(기관인증 필요)

초록보기

Background: Psoriasis is a chronic disease that can have accompanying comorbidities including arthritis, metabolic syndrome, and cardiovascular diseases. Patients with psoriasis tend to frequently visit medical institutions, and their economic burden for medical services is high.
Objective: To investigate the economic burden of psoriasis in Korea.
Methods: The Korean Society for Psoriasis conducted a multi-center field survey of the patients and analyzed the national insurance claim data. Also, we discussed the medical environment of psoriasis in Korea based on the results.
Results: The economic burden of psoriasis patients is substantial and varied by the type of medical institute. Patients also paid the indirect and intangible medical costs. Biological agents, which is used in patients with severe psoriasis, led to an increase in the cost.
Conclusion: This is the first study to estimate the economic burden of psoriasis in Korea comprehensively. To improve the medical environment of psoriasis and alleviate the burden of patients, discussion on the more efficient health policy and medical insurance criteria for psoriasis would be needed. (Korean J Dermatol 2021;59(5):321∼ 331)

KCI등재SCOUPUS

2신생아 집중치료실 환아에서 유아혈관종의 위험인자 분석

저자 : 오재홍 ( Jae Hong Oh ) , 김병윤 ( Byung Yoon Kim ) , 최미라 ( Mira Choi )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 332-340 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background: Infantile hemangioma (IH) is one of the most common tumors in infants. IH occurs more commonly in premature and low birth weight infants, but only a few studies have analyzed the risk factors for IH in neonatal intensive care units (NICUs) in Korea.
Objective: We investigated the risk factors for IH in patients admitted to the NICU at a single institution.
Methods: A single-center retrospective case-control study was conducted in 37 patients with hemangioma and 185 matched-control babies who were admitted to the NICU between 2013 and 2020. Odds ratios (ORs) and multivariate conditional logistic regression models were used to determine the associations between IH and the potential risk factors.
Results: Of the 1,206 neonates admitted to the NICU, 37 had IH, and the prevalence was 3.1%. IH was most commonly found on the trunk (33.3%), followed by the head and neck (29.4%). After adjustment, the risk factors found to be significantly associated with IH were female sex (OR=3.0, 95% confidence interval [CI]=1.4∼6.8), extreme preterm (OR=6.9, 95% CI=1.3∼38.0), very low birth weight (OR=11.9, 95% CI=2.9∼49.3), low 1-minute Apgar scores of <7 (OR=2.3, 95% CI=1.1∼4.9), and multiple gestation (OR=5.0, 95% CI=1.7∼14.9).
Conclusion: This matched case-control study revealed that risk factors such as female sex, extremely preterm birth, very low birth weight, low 1-minute Apgar score, and multiple gestations may affect the occurrence of IH. Therefore, if these risk factors are present, they need to be actively managed at an early stage through close physical examination to prevent complications. (Korean J Dermatol 2021;59(5):332∼340)

KCI등재SCOUPUS

3비전형적 피부섬유종의 임상적 특징과 더모스코피 소견에 관한 연구

저자 : 오하늘 ( Haneul Oh ) , 문혜림 ( Hye-rim Moon ) , 유화정 ( Hwa-jung Ryu ) , 김일환 ( Il-hwan Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 341-347 (7 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기

Background: Dermatofibroma is a common benign skin neoplasm that is usually easy to recognize; however, in some cases, it is difficult to differentiate it from atypical dermatofibroma. Atypical dermatofibroma is a rare variant of a more aggressive nature and requires complete excision due to its tendency to recur.
Objective: To describe the clinical and dermoscopic features of dermatofibromas with special emphasis on the characteristics of atypical subtypes and to differentiate them from typical subtypes on the basis of results.
Methods: We retrospectively searched the databases of patients of Korea University Ansan Hospital from January 2010 to December 2019 who underwent skin biopsies or excision surgeries and had pathological reports of dermatofibroma. Analyses of the clinical characteristics (age, sex, number of lesions, anatomical site) and dermoscopic patterns were performed.
Results: Dermoscopic patterns were analyzed in 148 cases of dermatofibroma; peripheral delicate pigment networks and central white scar-like patches were the most common patterns found in 45 cases (30.4%). In eight cases of atypical dermatofibroma, three cases (37.5%) showed peripheral homogenous areas and central white networks, followed by multiple white scar-like patches in 2 cases (25.0%), peripheral delicate pigment networks, and central white scar-like patches in 2 cases (25.0%). Dermoscopy revealed a statistically significant difference in the peripheral homogenous area and the central white network pattern between the two groups.
Conclusion: In this study, we analyzed the dermoscopic findings of 148 patients with dermatofibroma and found that the peripheral homogenous area and central white network patterns were significantly more in atypical dermatofibroma. (Korean J Dermatol 2021;59(5):341∼347)

KCI등재SCOUPUS

4세균에 의한 피부 감염증에서 항생제 감수성과 임상적 특징에 관한 연구

저자 : 이재호 ( Jae-ho Lee ) , 이수경 ( Soo-kyung Lee ) , 김명신 ( Myoung-shin Kim ) , 이운하 ( Un-ha Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 348-362 (15 pages)

다운로드

(기관인증 필요)

초록보기

Background: Bacterial skin soft-tissue infection is a common clinical manifestation in dermatology. The treatment of bacterial skin infections is often challenging due to antibiotic resistance, including methicillin resistance.
Objective: The aim of this study was to investigate the isolation rate of bacteria, antibiotic susceptibility, clinical features, and factors associated with treatment response in bacterial skin infections.
Methods: We retrospectively reviewed the medical records of patients who underwent ordinary bacterial skin cultures of the site of superficial skin infections between 2010 and 2019.
Results: A total of 1,298 patients were included in the study. The most commonly isolated bacteria were Staphylococcus aureus (31.3%), followed by coagulase-negative staphylococci (22.0%) and Pseudomonas species (4.2%). The methicillin-resistance rate of S. aureus was 22.7%. Crusted lesions (p=0.025), treatment with steroids (p=0.035), duration over 7 days (p=0.009), and isolation of Pseudomonas (p<0.001) or other uncommon species (non-Staphylococcus, Streptococcus, and Pseudomonas species, p<0.001) were significantly associated with treatment response.
Conclusion: The methicillin-resistance rate of S. aureus was similar to that of the past 5 years, but the mupirocin-resistance rate significantly increased. Lesions with crust or those that were treated with steroids showed good treatment responses, but longer disease durations of over 7 days and skin infections caused by Pseudomonas or other uncommon species were poor prognostic factors that should receive more attention. (Korean J Dermatol 2021;59(5):348∼362)

KCI등재SCOUPUS

5색소접촉피부염의 임상적 고찰 및 위험인자: 색소접촉피부염과 알레르기접촉피부염의 비교 분석

저자 : 김현빈 ( Hyeon Bin Kim ) , 윤숙정 ( Sook Jung Yun ) , 이승철 ( Seung-chul Lee ) , 이지범 ( Jee-bum Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 363-369 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: Pigmented contact dermatitis (PCD) is a non-eczematous contact dermatitis characterized by hyperpigmentation with few or no signs of dermatitis. The pathomechanism of PCD is still unknown; there are few case reports of PCD caused by hair dye, henna, and cosmetics.
Objective: This study aimed to analyze the clinical features and the significance of risk factors in adult Korean patients with PCD.
Methods: We retrospectively reviewed 75 patients with PCD. Clinical features including age, sex, duration, location, and risk factors were obtained from electronic medical records. To determine the significance of the risk factors of PCD, we compared these patients with 155 patients diagnosed with allergic contact dermatitis (ACD) without hyperpigmentation.
Results: The mean age of onset of PCD in patients was 55.5 years, and the male:female ratio was 1:14. The mean duration of PCD was 16.3 months. The number of patients with PCD who had histories of hair dye use (n=67, 89.3%) and health supplement consumption (n=18, 24.0%) was significantly higher than that of patients with ACD. There were no significant differences in medication, cosmetic changes, stress history, results of patch test, patch testing with the patient's own products, immunoglobulin E (kU/L), and eosinophils (cells/μL).
Conclusion: This study analyzed the clinical features and risk factors of PCD and ACD in adult Korean patients, and it suggests that PCD may be caused by irritation induced by variable factors and not allergic reactions. (Korean J Dermatol 2021;59(5):363∼369)

KCI등재SCOUPUS

6어루러기에서 경구 아졸계 항진균제의 치료 효과 비교: 체계적 문헌고찰 및 메타분석

저자 : 권륭 ( Ryung Kwon ) , 이설희 ( Sul Hee Lee ) , 박영립 ( Young Lip Park ) , 이상훈 ( Sang Hoon Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 370-378 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background: In pityriasis versicolor, systemic antifungal agents may be indicated for widespread or refractory lesions rather than topical treatment. Oral ketoconazole is an effective treatment for pityriasis versicolor. To our knowledge, this is the first meta-analysis to compare antifungal agents one-to-one.
Objective: To compare the effectiveness of oral azole antifungal agents (fluconazole, itraconazole, and ketoconazole) one-to-one in pityriasis versicolor.
Methods: A computerized search was performed in different databases, including PubMed, Cochrane, EMBASE, OVID Medline, KoreaMed, KISS, and MedRIC. Seven randomized controlled trials were included. Further, statistical analyses of the extracted outcome data from the studies were performed using Rex Software (ver. 3.0.1).
Results: A total of 1,828 records were identified. The results of the meta-analysis including seven studies revealed no significant differences in the mycological cure rates between fluconazole and ketoconazole (risk ratio [RR]: 1.01, 95% confidence interval [CI]: 0.93∼1.09, p=0.8246), fluconazole and itraconazole (RR: 1.14, 95% CI: 0.81∼1.60, p=0.4512), and ketoconazole and itraconazole (RR: 1.07, 95% CI: 0.96∼1.20, p=0.2265).
Conclusion: There was no superiority in the therapeutic effect of any drug among the oral azole antifungals used in pityriasis versicolor. (Korean J Dermatol 2021;59(5):370∼378)

KCI등재SCOUPUS

7만성광선피부염 환자에서 유병기간, 첩포검사 및 광첩포검사 결과와 최소홍반량 값과 임상적 중등도와의 상관관계

저자 : 김정환 ( Jung-hwan Kim ) , 김기호 ( Ki-ho Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 379-388 (10 pages)

다운로드

(기관인증 필요)

초록보기

Background: Chronic actinic dermatitis (CAD) is an uncommon eczematous photosensitivity disorder having a well-known relationship with allergic or photoallergic contact dermatitis. Moreover, the prognosis of CAD is worse in patients with lower minimal erythema doses (MEDs). However, the correlations between disease duration, contact and photocontact allergens, and MED values in CAD have not been reported.
Objective: To investigate the correlations among MED values, disease duration, and allergic patch/photopatch testing results and to elucidate the correlation between clinical severity and contact/photocontact allergens.
Methods: This study included 121 patients with CAD. Clinical data were analyzed according to the MED values, disease durations, and contact/photocontact allergens. Phototesting and patch/photopatch testing was performed in all the patients.
Results: The MED value was inversely correlated with disease duration for both MED-ultraviolet A and MED-ultraviolet B, with lower MED values for higher numbers of positive items in the patch/photopatch test. The most frequently detected allergens in the patch and photopatch tests were p-phenylenediamine (n=36, 9.3%) and Balsam of Peru (n=29, 21.3%). Clinically, patients demonstrating a greater number of detected allergens show poorer clinical severities (p<0.05).
Conclusion: The number of contact/photocontact allergens correlates with the severity of CAD. (Korean J Dermatol 2021;59(5):379∼388)

KCI등재SCOUPUS

8Reinfection Rate of Cutaneous Warts in Korea: A Nationwide Cross-Sectional Population-Based Study

저자 : Yeong Ho Kim , Kyungdo Han , Chul Hwan Bang , Ji Hyun Lee , Jun Young Lee , Yong Gyu Park , Young Min Park

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 389-393 (5 pages)

다운로드

(기관인증 필요)

초록보기

Background: Cutaneous warts tend to recur despite of various treatment modalities. However, previous studies provided few data on their reinfection rate.
Objective: In this study, we investigated the reinfection rate along with the incidence and prevalence rates of cutaneous warts.
Methods: We conducted a nationwide, cross-sectional population-based study using the Korean National Health Insurance Service database from January 2006 through December 2016. Patients who visited outpatient clinics with an International Classification of Disease-10 code of viral warts (B07) were included. The reinfection rate was calculated as a percentage of patients with an initial visit in 2010 and subsequent visits for cutaneous warts with at least a six-month interval from last visit until 2016.
Results: From 2006 to 2016, the overall incidence and prevalence rates of cutaneous warts increased from 2.99 to 7.69 per 1,000 population and from 3.45 to 10.94 per 1,000 population, respectively. The overall reinfection rate of cutaneous warts was 30.9%. The reinfection rate of males and females was 31.6% and 30.0%, respectively. Children under ten years old had the highest reinfection rate (34.3%).
Conclusion: These results demonstrate that the reinfection rate of cutaneous warts is the highest in male children under ten years old. Therefore, these patients should be monitored closely after treatment. (Korean J Dermatol 2021;59(5):389∼393)

KCI등재SCOUPUS

9Pustular Eruption Induced by Adalimumab in a Patient with Ankylosing Spondylitis: A Case Report

저자 : Ji-hoon Lim , Soon-hyo Kwon , Woo-young Sim , Bark-lynn Lew

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 394-397 (4 pages)

다운로드

(기관인증 필요)

초록보기

Many cutaneous adverse reactions including eczematoid dermatitis and lichenoid eruption have been reported with the increased usage of tumor necrosis factor-α inhibitors. However, there are very few reports of generalized pustular eruptions with adalimumab administration. A 44-year-old woman visited our clinic with multiple skin lesions scattered across her body. The patient developed these lesions three days after the initiation of adalimumab treatment. At the time of the patient's visit, physical examination revealed multiple erythematous papules and pustules across the body. Histopathological findings revealed subcorneal neutrophilic microabscess formation with dense perivascular and perifollicular infiltration that was mainly composed of lymphocytes and neutrophils. We diagnosed the patient with cutaneous pustular eruptions due to adalimumab exposure and initiated treatment with prednisolone and discontinued adalimumab injections. After 1 month of treatment, the patient's skin lesions improved. Herein, we report a case of generalized pustular eruptions, a rare cutaneous adverse reaction to adalimumab. (Korean J Dermatol 2021;59(5):394∼397)

KCI등재SCOUPUS

10A Case of Alopecia Areata in a Patient with Type I Pityriasis Rubra Pilaris

저자 : Dong Geon Lee , Hoon Kang , Jung Eun Kim

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 5호 발행 연도 : 2021 페이지 : pp. 398-400 (3 pages)

다운로드

(기관인증 필요)

초록보기

There have been a few cases of alopecia areata (AA) patients with pityriasis rubra pilaris (PRP), but the relationship between them is unclear. To the best of our knowledge, there have been no cases of co-occurrence reported in Korea. A 58-year-old male presented with multiple erythematous follicular papules and scaly plaques on the both legs with diffuse keratotic thickening on both palms and soles for several months. After skin biopsy, he was diagnosed with type I PRP. After treatment with oral and topical steroid, vitamin D3 analogue, oral alitretinoin, and urea cream for one week, multiple, diffuse alopecic patches appeared. He was diagnosed with AA after skin biopsy and we added topical minoxidil. Herein, we report a case of AA in a patient with type I PRP. (Korean J Dermatol 2021;59(5):398∼400)

12
발행기관 최신논문
자료제공: 네이버학술정보
발행기관 최신논문
자료제공: 네이버학술정보

내가 찾은 최근 검색어

최근 열람 자료

맞춤 논문

보관함

내 보관함
공유한 보관함

1:1문의

닫기