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KCI등재SCOUPUS

거대자궁근종의 1예

A case of giant myoma

구병삼(BS Koo) , 강재성(JS Kang) , 이제완(JW Lee) , 차종욱(CU Cha)
  • : 대한산부인과학회
  • : Obstetrics & Gynecology Science 18권1호
  • : 연속간행물
  • : 1975년 01월
  • : 85-88(4pages)
Obstetrics & Gynecology Science

DOI


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27세의 미산부에서 발생된 자궁근종이 국내에서 보고된 예에 비하여 가장 크다고 사료되는 9,120gm의 거대한 자궁근종을 수술로서 치료한 1례를 문헌고찰과 아울러 보고하는 바이다.
A case of great myoma in 27 year old nulliparous woman was presented and a briefly review on literature was noted.

UCI(KEPA)

I410-ECN-0102-2009-510-005386111

간행물정보

  • : 의약학분야  > 산부인과학
  • : KCI등재
  • : SCOPUS
  • : 격월
  • : 2287-8572
  • : 2287-8580
  • : 학술지
  • : 연속간행물
  • : 1958-2022
  • : 11141


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65권5호(2022년 09월) 수록논문
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KCI등재 SCOPUS

1Prenatal maternal alcohol exposure: diagnosis and prevention of fetal alcohol syndrome

저자 : Young Min Hur , Jiwon Choi , Sunwha Park , Sarah Soyeon Oh , Young Ju Kim

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 385-394 (10 pages)

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Fetal alcohol syndrome (FAS) is a developmental and congenital disorder characterized by neurocognitive impairment, structural defects, and growth restriction due to prenatal alcohol exposure. The estimated global prevalence of alcohol use during pregnancy is 9.8%, and the estimated prevalence of FAS in the general population is 14.6 per 10,000 people. In Korea, the estimated prevalence of alcohol use during pregnancy is 16%, and the prevalence of FAS is 18-51 per 10,000 women, which is higher than the global prevalence. Women's alcohol consumption rates have increased, especially in women of childbearing age. This could increase the incidence of FAS, leading to higher medical expenses and burden on society. Alcohol is the single most important teratogen that causes FAS, and there is no safe trimester to drink alcohol and no known safe amount of alcohol consumption during pregnancy. Thus, physicians should assess women's drinking patterns in detail and provide education on FAS to women by understanding its pathophysiology. Moreover, the prevention of FAS requires long-term care with a multidisciplinary approach.

KCI등재 SCOPUS

2Sentinel lymph node biopsy in high-risk endometrial cancer: performance, outcomes, and future avenues

저자 : Yoo-na Kim , Young Tae Kim

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 395-405 (11 pages)

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Endometrial cancer is the second most common gynecological malignancy worldwide, with an overall favorable prognosis. However, a subgroup of patients has a high risk of recurrence and poor prognosis. This review summarizes recently published articles that examined sentinel lymph node (SLN) biopsy in patients with high-risk endometrial cancer. We focused on the performance and outcomes of SLN biopsy, and examined potential methods for improving the management of this high-risk subset. Few studies have examined the long-term outcomes of SLN in patients with high-risk endometrial cancer. Thus, we reviewed recently published retrospective studies that have adopted statistical techniques, such as inverse probability weighting or propensity score matching, to examine the outcome of SLN biopsy compared to conventional lymphadenectomy. Potential avenues for future research to fine-tune decision making for this patient subgroup were also discussed.

KCI등재 SCOPUS

3Prophylactic tranexamic acid to reduce blood loss and related morbidities during hysterectomy: a systematic review and meta-analysis of randomized controlled trials

저자 : Ahmed Abu-zaid , Saeed Baradwan , Ehab Badghish , Rayan Alsghan , Ahmed Ghazi , Bayan Albouq , Khalid Khadawardi , Nora F Alnaim , Latifa F Alnaim , Meshael Fodaneel , Fatimah Shakir Abualsaud , Mohammed Ziad J

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 406-419 (14 pages)

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To perform a systematic review and meta-analysis of all randomized controlled trials (RCTs) that evaluated the efficacy and safety of prophylactic tranexamic acid (TXA) versus a control (placebo or no treatment) during hysterectomy for benign conditions. Six databases were screened from inception to January 23, 2022. Eligible studies were assessed for risk of bias. Outcomes were summarized as weighted mean differences and risk ratios with 95% confidence intervals in a random-effects model. Five studies, comprising six arms and 911 patients were included in the study. Two and three studies had an overall unclear and low risk of bias, respectively. Estimated intraoperative blood loss, requirement for postoperative blood transfusion, and requirement for intraoperative topical hemostatic agents were significantly reduced in a prophylactic TXA group when compared with a control group. Moreover, postoperative hemoglobin level was significantly higher in the prophylactic TXA group than in the control group. Conversely, the frequency of self-limiting nausea and vomiting was significantly higher in the prophylactic TXA group than in the control group. There were no significant differences between the groups in terms of surgery duration, hospital stay, and diarrhea rate. All the RCTs reported no incidence of major adverse events in either group, such as mortality, thromboembolic events, visual disturbances, or seizures. There was no publication bias for any outcome, and leave-one-out sensitivity analyses demonstrated stability of the findings. Among patients who underwent hysterectomy for benign conditions, prophylactic TXA appeared largely safe and correlated with substantial reductions in estimated intraoperative blood loss and related morbidities.

KCI등재 SCOPUS

4Ritodrine in external cephalic version: is it effective and safe?

저자 : Sin Ae Kim , Eun-hwan Cha , Kyoung-chul Chun , Young Ah Kim , Jae-whoan Koh , Jung Yeol Han , Jong Hee Hwang

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 420-429 (10 pages)

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Objective
The external cephalic version (ECV) has been shown to lower the likelihood of cesarean section requirements among pregnant women with breech presentations. In the current study, we investigated the effectiveness and safety of ritodrine as a tocolytic for ECV.
Methods
A total of 407 pregnant women with breech presentations, who had no contraindications for ECV, were enrolled in this study. Multivariable logistic regression analyses were used to assess the impact of ritodrine use on the safety and efficacy of ECV.
Results
The overall success rate was 67.6%, and ritodrine use was associated with significantly higher odds of successful ECV after adjusting for confounders. Moreover, using ritodrine did not increase the risk of adverse effects, including temporary changes in fetal heart rate, need for elective or emergency cesarean section due to fetal distress during ECV, low Apgar scores, and perinatal mortality.
Conclusion
Our results suggest that using ritodrine as a tocolytic during ECV may increase the likelihood of ECV success and may not increase adverse perinatal outcomes.

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Objective
To determine the value of endometrial thickness (ET) and Doppler indices of uterine artery (UtA) as sonographic markers in predicting endometrial cancer (EC) among postmenopausal bleeding (PMB) women in low-resource settings as Vietnam.
Methods
This cross-sectional study was conducted at the Hue University Hospital and Hue Central Hospital between June 2016 and June 2019. The study enrolled all women who complained of PMB and were followed by transvaginal Doppler ultrasound. Their definitive histopathological examination was the gold standard for comparison.
Results
The UtA Doppler indices, including resistance index (RI), pulsatility index (PI), and peak systolic velocity (PSV), were significantly lower in the malignant group than in the benign group. The threshold values of the UtA, RI ≤0.73 and PI ≤1.42, were found with an area under receiver operating characteristic curve (AUC) of 0.85-0.88, and the sensitivity and specificity were 91.3% and 83.3%, respectively. Unlike PSV, the diagnostic value was the lowest, with an AUC of 0.72. ET was a good predictor for the diagnosis of EC, with an AUC of 0.89. In women with PMB, when using the cutoff value of EC more than 12.5 mm, the sensitivity and specificity were 93.8% and 77.8%, respectively. In addition, the higher the stage of EC, the lower the RI and PI and the greater the EC.
Conclusion
ET, and RI, PI, and PSV of the UtA could help in differentiating malignant from benign endometrial changes. Pulsed ultrasonic Doppler velocimetry seems to play a role in predicting the higher stages of EC. Further studies are needed to confirm these findings.

KCI등재 SCOPUS

6The effect of a support program on the burden of spouses caring for their partners with breast cancer: a randomized controlled trial

저자 : Seyedeh-zeynab Hosseinnejad , Forouzan Elyasi , Seyed-nouraddin Mousavinasab , Zohreh Shahhosseini

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 441-450 (10 pages)

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Objective
This study aimed to determine the effect of a support program on burden of spouses caring for their partners with breast cancer.
Methods
This randomized controlled trial was conducted among spouses of women with breast cancer undergoing chemotherapy at a referral chemotherapy center in Iran. They were assigned to intervention (n=40) and control (n=40) groups using permuted block randomization. Three small group sessions lasted 45-60 minutes, followed by three telephone-based sessions, lasting 15-20 minutes (twice a week). The intervention sessions included defining stress management strategies in different situations: strengthening creativity, optimism, and management in planning, and defining the role of the caregiver. Primary outcome was care burden, and secondary outcomes were spouses' stress, satisfaction with intervention, and partners' quality of life (QOL). The caregiver burden inventory, depression anxiety stress questionnaire, World Health Organization QOL brief version, and client satisfaction questionnaire were completed before and after the intervention and at a 6-week follow-up.
Results
Thirty-eight participants in each group with a mean age of 44.24±9.01 years completed the study. Repeated measures analysis of variance showed a significant difference in the care burden (P<0.05; effect size, 0.70), stress (P<0.05; effect size, 0.64), and women's QOL (P<0.05; effect size, 0.67) before and after the intervention.
Conclusion
The results of this study can be used to develop interventions, targeting the care burden and stress of spouses of women with breast cancer undergoing chemotherapy.

KCI등재 SCOPUS

7Predictive value of 'Smartscopy' for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study

저자 : Thamawoot Phoblap , Amornrat Temtanakitpaisan , Apiwat Aue-angkul , Pilaiwan Kleebkaow , Bandit Chumworathayi , Sanguanchoke Luanratanakorn , Yuwadee Itarat

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 451-458 (8 pages)

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Objective
To evaluate the performance of “Smartscopy” in diagnosing preinvasive cervical lesions among patients with abnormal cervical cancer screening results obtained during the coronavirus disease 2019 (COVID-19) pandemic.
Methods
This diagnostic study enrolled non-pregnant women with abnormal cervical cancer screening results obtained at the colposcopy clinic at Srinagarind Hospital (Khon Kaen, Thailand) between September 2020 and March 2021. Two colposcopists independently evaluated the uterine cervix using a smartphone and colposcopy. Cervical biopsies and endocervical curettage were performed in accordance with standard procedures. The diagnostic performance of a smartphone in detecting low-grade squamous intraepithelial lesions or worse plus (LSIL+) and high-grade squamous intraepithelial lesions plus (HSIL+) was assessed.
Results
In total, 247 patients were included. There was high agreement between the two colposcopists (κ=0.88; 95% confidence interval [CI], 0.82-0.93). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the smartphone to detect LSIL+ were 96.6% (95% CI, 91.6-99.1), 12.9% (95% CI, 8.06-19.2), 46.2% (95% CI, 39.7-52.4), 83.3% (95% CI, 62.6-95.3), and 0.49% (95% CI, 0.43-0.55), respectively. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of smartscopy in diagnosing HSIL+ were 67.6% (95% CI, 55.2- 78.5), 85.4% (95% CI, 79.9-90.0), 60.5% (95% CI, 48.6-71.6), 88.9% (95% CI, 83.7-92.9), and 81.0% (95% CI, 0.75-0.85), respectively.
Conclusion
Smartscopy demonstrated a remarkable correlation with colposcopy and a high diagnostic performance value for the detection of preinvasive cervical lesions. Therefore, smartscopy may be an alternative tool for detecting abnormal cervical lesions in low to medium medical resource settings. Smartscopy may be applied in telemedicine during the COVID-19 pandemic.

KCI등재 SCOPUS

8Clinical outcomes of immunohistochemistry of the p53 staining pattern in high-grade serous ovarian carcinoma

저자 : Panarat Orachum , Amornrat Temtanakitpaisan , Pilaiwan Kleebkaow , Bandit Chumworathayi , Sanguanchoke Luanratanakorn , Apiwat Aue-angkul , Yuwadee Itarat

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 459-467 (9 pages)

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Objective
To investigate the prevalence of p53 mutations and associated factors between immunohistochemistry (IHC) and p53 staining patterns among patients with high-grade serous ovarian carcinoma (HGSOC).
Methods
This study is a retrospective review. A total of 62 patients with HGSOC underwent surgery at Srinagarind Hospital between January 2016 and December 2020. Histological examination was performed based on a combination of morphology and IHC staining with p53. The p53 immunostaining pattern was interpreted as a missense mutation, nonsense mutation, or a wild-type pattern. Missense (p53 overexpression pattern) and nonsense (null expression p53 pattern) mutations were considered p53 mutations. A wild-type pattern was defined as a p53 non-mutation.
Results
p53 mutations were identified in 93.6% of the patients. Subgroup analysis of the p53 mutation group between the p53 overexpression pattern and the p53 null expression pattern in terms of clinicopathological characteristics and initial treatment was performed. Patients with the p53 overexpression pattern had significantly more omental metastases than those with the p53 null expression pattern (87.8% vs. 64.7%, P=0.042). There were no statistically significant differences in median progression-free survival (PFS) (9 vs. 10 months, P=0.813) or median overall survival (OS) (12 vs. 17 months, P=0.526) between the two groups.
Conclusion
The prevalence of p53 mutations in HGSOC patients in this study was 93.6%. Omental metastasis is a significant pathological factor in predicting overexpression p53 pattern in HGSC. However, IHC analysis of the p53 staining pattern did not affect OS or PFS among patients with HGSOC.

KCI등재 SCOPUS

9Body fat distribution and insulin resistance among Korean middle-aged women: a Korean National Health and Nutrition Examination Survey

저자 : Sae Mi Lee , Ki-jin Ryu , Serhim Son , Yeon Ju Lee , Hyuntae Park , Tak Kim

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 468-476 (9 pages)

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Objective
To evaluate menopause-related changes in body fat distribution and their relationship with insulin resistance in middleaged Korean women.
Methods
We analyzed women aged 40-60 years using data from the National Health and Nutrition Examination Survey conducted from 2008 to 2011. Body fat was measured using dual-energy X-ray absorptiometry. Insulin resistance was assessed using the homeostasis model assessment of insulin resistance (HOMA-IR).
Results
Among 3,468 participants, menopausal women (n=1,489) had a higher body mass index (BMI) and higher trunk, arm, and head fat percentages than premenopausal women (n=1,979). However, no significant difference was found in the leg fat percentage according to menopausal status. Multivariable regression analysis for HOMA-IR showed that trunk fat percentage, BMI, and waist circumference positively correlated with insulin resistance and leg fat percentage negatively correlated after adjusting for several confounding factors, whereas menopausal status was not associated with HOMA-IR.
Conclusion
Middle-aged women not only have different body weights and BMI but also have different body fat distributions according to menopausal status. Each fat percentage change in the trunk and leg is differently associated with metabolic health, particularly insulin resistance. To evaluate the metabolic health of middle-aged women, BMI is generally noted; however, body fat distribution, which can be easily assessed using dual-energy X-ray absorptiometry, should also be considered.

KCI등재 SCOPUS

10Vaginal vault drainage as an effective and feasible alternative in laparoscopic hysterectomy

저자 : Soohyun Oh , Seung Joo Chon , Seung Ho Lee , Jin Woo Shin

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 65권 5호 발행 연도 : 2022 페이지 : pp. 477-482 (6 pages)

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Objective
Infected pelvic hematoma is a serious complication of hysterectomies. Pelvic drainage can help reduce complications. In this study, we evaluated the efficacy and safety of vaginal vault drainage in patients who underwent laparoscopic hysterectomy for benign gynecological diseases.
Methods
Patients who underwent laparoscopic hysterectomy and pelvic drain insertion for benign gynecological diseases between January 2008 and December 2015 were enrolled retrospectively in the study. They were grouped according to drain insertion sites, that is, through the abdomen (group 1) and vaginal vault (group 2). The postoperative outcomes were compared between the two groups.
Results
A total of 504 women were included. No significant differences were observed in the prevalence of postoperative fever, readmission, and reoperation between the two groups.
Conclusion
Given the discomfort associated with holding and removing the abdominal drain, inserting a closed pelvic gravity drain through the vaginal vault appears to be a feasible alternative to an abdominal drain.

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KCI등재SCOUPUS

1산모와 신생아의 적혈구막 단백질에 관한 비교 연구

저자 : 권순욱(SW Kwon) , 이원기(WK Lee) , 조용호(YH Cho)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 1-10 (10 pages)

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이상과 같은 실험성적으로 미루어 봐서 산모와 신생아의 적혈구막단백질의 구성 단백분획이 서로 차이가 있음을 알았다. 그리고 이러한 막단백분획의 차이는 산모와 신생아가 서로 다른 조혈기관에서 적혈구를 생성하는 것으로 시사한다.

KCI등재SCOUPUS

2정상 및 이상임신 혈청중 Cystine Aminopeptidases 의 활성도에 관한 연구

저자 : 김현준(HC Kim)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 11-26 (16 pages)

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CAP 활성도는 대체로 임신중 점진적으로 증가하고 태반의 중량과 상관관계가 있었으며 CAP 활성도측정은 태반기능상태를 측정하는 방법중 하나의 의의있는 검사법이라고 사료되었다.

KCI등재SCOUPUS

3자궁경의 질확대경검사법에 관한 연구

저자 : 백성현(SH Baik)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 27-40 (14 pages)

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향후 우리나라에서도 부인과진찰암에 특히 자궁경암의 조기검진에 있어서 세포학적검사, 조직학적검사에다 질확대경검사를 이용하면 진단의 정확성을 더욱 증가시킬 것으로 생각한다.

KCI등재SCOUPUS

4삼투자극이 자궁운동성에 미치는 영향

저자 : 최갑식(KS Choi)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 41-52 (12 pages)

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장상군, estrogen투여군, estrogen 및 progesterone 병용군에서 대체로 비슷한 반응을 보임으로써 이들 호르몬이 자궁근의 삼투자극에 대한 반응태도에는 크게 영향을 주지 않는 것 같이 보였다.

KCI등재SCOUPUS

5거대아 분만산모의 정맥당부하시험과 K-value에 관한 관찰

저자 : 박종학(JK Park) , 최성기(SK Choi)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 53-56 (4 pages)

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체중 4.0kg이상을 분만한 57명의 산모에게 분만후 24시간이내에 정맥당부하시험을 시행했던바, 적절한 검사를 할 수 있었던 50명의 산모중 정상 K-value는 60% questionable K-value는 32%, abnormal k-value는 8%였다. 년령군별 K-value의 큰 차이점은 없엇고 26-30세군에서 abnormal K-value가 17.6%에 이르렀다. 분만횟수별 당부하시험에서는 분만횟수의 증가에 따른 K-value상의 변화를 볼 수 없었다.

KCI등재SCOUPUS

6양수의 Creatinine, Sodium, Potassium 및 Chloride농도의 동태

저자 : 최영실(YS Chey) , 정태조(TJ Chung) , 신동삼(DM Sin)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 57-64 (8 pages)

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N/A
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자간전증 및 자간증군에 잇어서 양수내 Na의 농도는 혈청내 농도보다 유의하게 낮았으며 Cl, K 농도는 차이가 없었다.

KCI등재SCOUPUS

7남성반음양 ( Male Hermaphroditism ) 에 실시한 질성형술 1예

저자 : 이수종(SJ Lee) , 구병삼(BS Koo) , 나종열(JY Rha) , 강재성(JS Kang) , 최영열(YY Choe)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 65-70 (6 pages)

다운로드

(기관인증 필요)

키워드 보기
N/A
초록보기

외생식기관의 기형을 동반한 환자의 염색체검사 및 생식선 생검결과 여성화된 남성반음양으로 진단되었으며, 대음순 상부에 위치한 환을 제거하고 McIndoe술식에 의한 질을 형성하여 좋은 결과를 얻었기에 1례를 보고하는 바이다.

KCI등재SCOUPUS

8조질술 1예

저자 : 박덕수(DS Park) , 김현호(HH Kim) , 이건국(KK Lee) , 곽태노(TR Kwaik)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 71-76 (6 pages)

다운로드

(기관인증 필요)

키워드 보기
N/A
초록보기

선천성무질증에서 시도했던 McIndoe술식에 의한 인공 조질술1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

KCI등재SCOUPUS

9정상임신중 합병된 원발성융모암의 1예

저자 : 정태조(TJ Chung) , 신동삼(DM Sin) , 박인사(IS Park) , 최영실(YS Chey)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 77-80 (4 pages)

다운로드

(기관인증 필요)

키워드 보기
N/A
초록보기

저자들은 24세의 초임부가 융모암을 병발하여 임신 34주에 정상분만후 화학요법으로 치료하는 도중에 사망한 1례를 경험하였기에 문헌적 고찰과 함께 이에 보고하는 바이다.

KCI등재SCOUPUS

10경관임신의 1예

저자 : 김종목(JM Kim) , 김이민(LM KIM) , 이후영(HY Lee) , 이병준(BC Rhee)

발행기관 : 대한산부인과학회 간행물 : Obstetrics & Gynecology Science 18권 1호 발행 연도 : 1975 페이지 : pp. 81-84 (4 pages)

다운로드

(기관인증 필요)

키워드 보기
N/A
초록보기

저자들은 불완전유산이라는 진단하에 2개 의원을 거쳐 전혈 20 pints(9000ml)를 수혈하고 본원에서 수술하여 병리학적으로 확진을 하고 완결 근원한 1례를 치험아엿기에 문헌적 고찰과 아울러 보고하는 바이다.

12
발행기관 최신논문
자료제공: 네이버학술정보
발행기관 최신논문
자료제공: 네이버학술정보

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