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대한본초학회지(본초분과학회지) update

The Korea Jounrnal of Herbology

  • : 대한본초학회
  • : 의약학분야  >  기초한의학
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수록정보
수록범위 : 1권0호(1986)~36권4호(2021) |수록논문 수 : 1,636
대한본초학회지(본초분과학회지)
36권4호(2021년 07월) 수록논문
최근 권호 논문
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KCI등재

1우슬의 에탄올 추출물이 모발 성장에 미치는 영향

저자 : 이미자 ( Mi-ja Lee ) , 최문열 ( Moon-yeol Choi ) , 김유진 ( Yoo Jin Kim ) , 김미려 ( Mi Ryeo Kim ) , 유왕근 ( Wang Keun Yoo )

발행기관 : 대한본초학회 간행물 : 대한본초학회지(본초분과학회지) 36권 4호 발행 연도 : 2021 페이지 : pp. 1-7 (7 pages)

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Objective : As more and more people are interested in appearance in modern society, the increasing number of hair loss population can have an important impact on psychological and social problems such as depression and inappropriate interpersonal symptoms. Therefore, much research is being done on treatments for alopecia using herbal extracts with relatively few side effects. This study was investigated about the effect of Achyranthis Radix (AR) extract with ethanol solvent on hair growth.
Methods : We determined the promoting efficacy of AR-ethanol extract compared with minoxidil (MNXD) on the growth of human hair dermal papilla cells (HDPCs). Cell viability was measured by MTT assay and cell proliferation was confirmed by cell cycle analysis from flow cytometry in HDPCs. Also, we monitored the safe concentration range through MTT assay. And protein expression of hair growth-related genes (insulin-like growth factor 1 (IGF-1), Wnt3a, Protein kinase B (Akt), Extracellular signal-regulated kinase (Erk)) was monitored by western blot.
Results : On cell cycle analysis, the G2/M phase was higher than that of the DW group in AR ethanol extract group at 0.05 and 0.1 ㎎/㎖. All protein expression levels of HDPCs were increased in AR ethanol extract groups and the MNXD group, compared to the DW group, respectively.
Conclusion : As mentioned above, AR extract increased cell proliferation and the protein expression of IGF-1, Wnt3a, Akt, Erk in HDPCs. These results suggest that AR ethanol extract has promoted hair growth and it might be potential hair growth supplement.

KCI등재

2한국에서 자생하는 갈조식물문에 관한 본초학적 연구

저자 : 전의상 ( Ui Sang-jeon ) , 정종길 ( Jong-gil Jeong )

발행기관 : 대한본초학회 간행물 : 대한본초학회지(본초분과학회지) 36권 4호 발행 연도 : 2021 페이지 : pp. 9-22 (14 pages)

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Objective : The purpose of this dissertation is to make a list of the phaeophyta growing naturally in the Korean coastal waters, and to carry out a survey on the current distribution status to investigate the phaeophyta which can be used as medicinal herbs.
Methods : References and research papers about herbology published at home and abroad were examined.
Results : The results of this study were as follows : A total of 63 genera and 145 species of phaeophyta was found in the Korean coastal waters among which 11 genera and 15 species(approximately 11%) were medicinal plants. Out of the 145 species of phaeophyta 27 species belonged to Sargassum, and out of the 15 species of medicinal plants 4 species belonged to Sargassum. Among the medicinal parts 11 species belonged to algae. Sixteen species had cold property, and 16 species had salty flavors. Thirteen species had the efficacy of liver meridian, and 15 species had the potency of YEONKYUN, which helps to remove hard clots generated in human body. No toxic drugs were detected.
Conclusion : There were totaled to 63 genera and 145 species in Phaeophyta in Korea and among them medicinal plants are 11 genera, 15 species, some 11% in total. Thirteen species had the efficacy of liver meridian, and 15 species had the potency of YEONKYUN, which helps to remove hard clots generated in human body. No toxic drugs were detected.

KCI등재

3Paenibacillus kribbensis AM49로 발효시킨 택사의 항산화 활성 및 NO 생성 효과

저자 : 유동진 ( Dong-jin Yoo ) , 김창은 ( Chang-eun Kim ) , 유수정 ( Soo-jung Yoo ) , 전문희 ( Moon-hee Jeon ) , 김수현 ( Soo-hyun Kim )

발행기관 : 대한본초학회 간행물 : 대한본초학회지(본초분과학회지) 36권 4호 발행 연도 : 2021 페이지 : pp. 23-30 (8 pages)

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Objectives : The purpose of this study was to investigate the antioxidant activities and nitric oxide (NO) production in RAW 264.7 macrophages in extract of Alisma orientale Juzep (EAOJ) and fermented extract (FAOJ) by Paenibacillus kribbensis AM49 (P. kribbensis AM49).
Methods : The Alisma orientale Juzep was fermented with P. kribbensis AM49 at 37℃ for 72 hours. We measured total polyphenol and total flavonoid, DPPH radical scavenging activity, FRAP activity and reducing power by spectrometric assay in EAOJ and FAOJ at concentrations at 0.5, 1, 5, 10 ㎎/㎖. Positive control was used ascorbic acid. Furthermore, we examined effect of EAOJ and FAOJ on the cell viability and NO production in RAW 264.7 macrophages.
Results : The total polyphenol and total flavonoids content of FAOJ were increased 9.16 ㎎/g, 2.59 ㎎/g to 12.58 ㎎/g, 3.45 ㎎/g. DPPH radical scavenging activity, FRAP activity and reducing power were dose dependently increased according to the treatment concentration (0.5, 1, 5, 10 ㎎/㎖) of EAOJ and FAOJ. In particular, DPPH radical scavenging activity, FRAP activity of FAOJ was significantly increased at 5, 10 ㎎/㎖. Reducing power of FAOJ at 10 ㎎/㎖ was similar to ascorbic acid at 0.1 ㎎/㎖. In addition, the cell viability and NO production in RAW 264.7 macrophages were significantly increased at the concentrations of 250, 500, 1000 ㎍/㎖.
Conclusions : These results suggest that FAOJ by P. kribbensis AM49 has effects to antioxidant activity. In addition, the cell viability and NO production in RAW 264.7 macrophages were significantly increased.

KCI등재

4미세다륜침을 이용한 인삼추출물의 피부개선 효과연구

저자 : 구진숙 ( Jin Suk Koo )

발행기관 : 대한본초학회 간행물 : 대한본초학회지(본초분과학회지) 36권 4호 발행 연도 : 2021 페이지 : pp. 31-39 (9 pages)

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Objectives : The purpose of this study was to find out the efficacy of ginseng on the skin by comparing the difference effect between only MTS (microneedle therapy system) and the ginseng solution application after MTS treatment.
Methods : The present author performed once a week and total 3 times of MTS treatment. The treatment time took about 5~10 minutes and the depth of the needle was adjusted according to the participant's skin condition. In the control group, skin toner was applied after MTS and in the experimental group, ginseng extract dissolved toner was applied. One week after each treatment, the change of skin condition was measured. Two weeks after the end of the clinical trial, the skin condition was checked again.
Results : In the case of t-zone oil, there was a significant decrease in the test group and in the case of pores and pigmentation, there was a significant decrease in both the test group and the control group, but the degree of significance was greater in the test group. In the case of skin tone, there was an increase, but no significance.
Conclusion : The MTS treatment itself showed good effects on t-zone oil, pores, pigmentation, and skin tone. But the effect was much better when the ginseng extract solution was applied to the skin after MTS treatment. This study suggests that ginseng solution increases the efficacy of MTS.

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5사향의 크로마토그램 패턴 분석을 통한 품질비교 연구

저자 : 조종운 ( Chong Woon Cho ) , 가오단 ( Gao Dan ) , 강종성 ( Jong Seong Kang ) , 정효원 ( Hyo Won Jung ) , 박용기 ( Yong-ki Park )

발행기관 : 대한본초학회 간행물 : 대한본초학회지(본초분과학회지) 36권 4호 발행 연도 : 2021 페이지 : pp. 41-50 (10 pages)

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Objectives : This study is to check the quality of Moschus products in Korean markets using a chromatographic analysis.
Methods : We collected musk products, two genuine products from Russia (A, B), two authentic products from Hong Kong (C) and Korea (D), the Ministry of Food and Drug Safety (MFDS) standard (E), and two fire ants products (E, F).
Results : For identification, TLC analysis of 60% ethanol extracts of each product showed that A, B, C, and E have the suitable patterns before color development at 365 nm UV light for the MFDS regulation in Korea. A clear red spot was observed from the E at Rf 0.6 with 365 nm UV light after color development, but this spot was not found in A and B. For the purity test, a distinct violet spot with Rf 0.87 was observed from the A and B in TLC analysis of methanol extracts of each product at white light, however, this spot was not matched with the impurities of E and F. In HPLC-UV pattern analysis, a similar peak pattern was shown in A, B and E, and similar peaks were observed C, although the similarity was weaker than that of A, B, and E. The F and G showed different peak patterns compared with the peak patterns of other samples.
Conclusions : Hence, it is considered that the test methods need flexibility in application for identification and purity test depending on the type of sample.

KCI등재

6논문 철회 : 고지방식이 비만마우스 모델에서 파키스탄산 및 중국산 마황으로 조성된 降脂丸-1,2,3,4과 降脂丸-1+加味消滯丸의 비알콜성 지방간질환 개선효과 비교

저자 : 정양삼 , 김종훈 , 김병출 , 석화준 , 유재상 , 구자룡 , 윤기현 , 조주흠 , 장두현 , 윤호영 , 윤미정 , 신순식

발행기관 : 대한본초학회 간행물 : 대한본초학회지(본초분과학회지) 36권 4호 발행 연도 : 2021 페이지 : pp. 51-51 (1 pages)

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