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The Journal Of Oriental Gynecology

  • : 대한한방부인과학회
  • : 의약학분야  >  기초한의학
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  • : 1229-4292
  • : 2508-3619
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수록정보
수록범위 : 1권1호(1987)~35권3호(2022) |수록논문 수 : 1,268
대한한방부인과학회지
35권3호(2022년 08월) 수록논문
최근 권호 논문
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KCI등재

저자 : 류효경 ( Hyo-kyung Ryu ) , 정민재 ( Min-jae Jung ) , 조성희 ( Seong-hee Cho )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 1-23 (23 pages)

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Objectives: The purpose of this study is to evaluate anti-breast cancer and anti-inflammatory effects of Chungganhaewool-tang and Shipyeukmiyeugi-eum.
Methods: MDA-MB-231 cells were used to measure cytotoxicity, Reactive oxygen
species (ROS) production, protein expression amounts of Bcl-2-associated X protein (Bax), B-cell lymphoma 2 (Bcl-2), B-cell lymphoma-extra large (Bcl-xl), Cytochrome C Caspase-3, Caspase-7, Caspase-9, Poly ADP-ribose polymerase (PARP), Nuclear factor erythroid-2-related factor 2 (Nrf2), Heme oxygenase-1 (HO-1) and NAD (P) H Quinone Oxidoreductase 1 (NQO1) to evaluate the anti-breast cancer effects of Chungganhaewool-tang (CHT) and Shipyeukmiyeugi-eum (SYE), and THP-1 cells, differentiated into macrophage and induced inflammation with Lipopolysaccharide (LPS), were used to measure production amounts of ROS, Nitric oxide (NO), and protein expression amounts of Inducible nitric oxide synthase (iNOS), Cyclooxygenase (COX-2), Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6) and Tumor necrosis factor-alpha
(TNF-α) to evaluate the anti-inflammatory effects of CHT and SYE.
Results: CHT and SYE reduced MDA-MB-231 cell counts, increased protein expression of Bax and Cytochrome C, and decreased protein expression of Bcl-2, Bcl-xl. The protein expression amounts of Caspase-3, 7, and 9 decreased, but amounts of the active form, cleaved Caspase-3, 7, and 9, increased. In addition, PARP protein expression decreased, the amount of PARP protein in the cleaved form increased, and the amount of protein expressions of Nrf2 and HO-1 decreased, but NQO1 showed no significant difference. In THP-1 cells CHT and SYE reduced ROS and NO, and reduced protein expressions of iNOS, COX-2, IL-1, and TNF-α, but only SYE groups reduced IL-6.
Conclusions: This study suggests that CHT and SYE have potential to be used
as treatments for breast cancer.

KCI등재

저자 : 이윤정 ( Yun-jung Lee ) , 송현우 ( Hyun-woo Song ) , 이보리 ( Bo-ri Lee ) , 나혜림 ( Hye-rim Na ) , 송봉준 ( Bong-joon Song ) , 이영미 ( Young-mi Lee )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 24-36 (13 pages)

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Objectives: Excessive melanin production leads to skin pigmentation, which causes various cosmetic and health problems. Citrus unshiu Markovich peel (CS) and Cimicifuga dahurica (CD) have long been widely used as a oriental medicinal plant because of their pharmacological properties including anti-ulcer, anti-oxidant, and anti-inflammatory properties.
Methods: In this study, we investigated the inhibitory effects of CS, CD extracts or CS:CD=1:2 mixture on melanogenesis according to the various extraction methods. CS and CD extracted were prepared by ethanol extraction (EE), ultrasonification extraction (USE), Supercritical extraction (SCE), reflux extraction (RE), respectively.
Results: DPPH radical scavenging and tyrosinase inhibitory activity of CD extracts or CS:CD=1:2 mixture were increased in dose-dependent manners. In addition, we evaluated the effect of CS, CD extracts or CS:CD=1:2 mixture on tyrosinase activity and melanogenesis in α-melanocyte stimulating hormone-induced B16-F10 melanoma cells. CS, CD extracts or CS:CD=1:2 mixture significantly inhibited tyrosinase activity and melanogenesis at 10-200 μg/mL.
Conclusions: Therefore, our study suggests that CS and CD extracts have potential as a safe treatment for excessive pigmentation or as a natural ingredient in cosmetics.

KCI등재

저자 : 이수형 ( Soo-hyung Lee ) , 김송백 ( Song-baek Kim )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 37-55 (19 pages)

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Objectives: The purpose of this study is to investigate the efficacy and safety of acupuncture on postpartum urinary incontinence.
Methods: 'postpartum urinary incontinence', 'postnatal urinary incontinence', 'acupuncture' were searched on 4 online databases (Cochrane Library, Pubmed, CNKI, OASIS). Randomized controlled trials (RCTs) that used acupuncture on postpartum urinary incontinence were included. The methodological quality of each RCT was assessed by using Cochrane risk of bias tool.
Results: 12 RCTs were finally selected. The overall risk of bias was evaluated as uncertain. 11 studies showed that combined treatment group was better than control group in effective rate and/or ICIQ-SF total score, but among those 1 study was not statistically significant in ICIQ-SF total score. In the comparison of alone treatment group and control group, 1 study showed favorable effect in ICIQ-SF total score, but 1 study was not significant in effective rate.
Conclusions: Treatment that include acupuncture can effect on postpartum urinary incontinence. but considering quality of studies, inconsistent and insufficient evidence, further well-designed studies are needed to confirm the efficacy and safety of this treatment.

KCI등재

저자 : 나지영 ( Jee-young Na ) , 박장경 ( Jang-kyung Park ) , 윤영진 ( Young-jin Yoon )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 56-73 (18 pages)

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Objectives: This study was aimed to review the effect of acupuncture for insomnia in climacteric syndrome.
Methods: Researchers searched data through 5 online databases up to December 2021. The data was limited to randomized controlled trial studies on patients diagnosed with insomnia in climacteric syndrome.
Results: 8 Randomized controlled trials were included in this study. 6 of studies were published in Chinese, in China. 2 were published in English. Intervention of treatment group were composed of simple acupuncture. Intervention of control group were made up with Estazolam, Alprazolam, Lorazepam and sham-acupuncture. Outcome measurements were Total effective rate, Pittsburgh Sleep Quality Index (PSQI), Kupperman index, Menopause Quality of Life scales (Men-QoL), the level of hormones (E2, FSH, LH) etc. In all outcome measurements, treatment group were more effective than control group and it was statistically significant.
Conclusions: Acupunture therapy is effective for treating insomnia in climacteric syndrome. Pittsburgh Sleep Quality Index (PSQI) is most frequently used for sleep assessment indicator. 神門(HT7) is the most frequently used acupoint for treatment group. However because insomnia in climacteric syndrome is easy to recur, additional long-term research is needed.

KCI등재

저자 : 이지원 ( Ji-won Lee ) , 김동철 ( Dong-chul Kim )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 74-87 (14 pages)

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Objectives: This study was performed to analyze the domestic study trends on abnormal uterine bleeding treated with Korean medicine.
Methods: We searched the studies of abnormal uterine bleeding treated with Korean medicine via searching four Korean web databases. After that, we analyzed 15 studies which were selected according to the selection and exclusion criteria.
Results: All 15 selected studies were case reports, and the total number of patients included was 33. Herbal medicine was used in all patients, and Igwiseungyang-tang-gami and Jeonsaenghwalhyol-tang-gami were the most commonly used. Other Korean medicine treatment such as acupuncture and moxibustion were performed. Acupuncture point most frequently used in acupuncture treatment were 三陰交(SP6), 太衝 (LR3), 合谷(LI4), and in moxibustion treatment were 關元(CV4), 中脘(CV12), 氣海(CV6). In all studies, uterine bleeding was reduced after treatment.
Conclusions: This study shows that Korean medicine could be helpful in treating abnormal uterine bleeding. In order to increase the basis for clinical use in the future, high quality of additional studies should be conducted.

KCI등재

저자 : 윤희재 ( Hee-jae Yoon ) , 김혜원 ( Hae-won Kim ) , 이지연 ( Ji-yeon Lee ) , 유정은 ( Jeong-eun Yoo )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 88-104 (17 pages)

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Objectives: The purpose of this study is to report the effectiveness and satisfaction of traditional Korean medicine (TKM) for enhanced recovery after surgery (ERAS) after gynecological surgery.
Methods: The study is conducted by analyzing the medical records of hospitalized patients in a Korean medicine hospital. Sixty-five patients who received TKM for ERAS after gynecological surgery from May 2020 to July 2021 were included. We performed statistical analysis by using SPSS ver. 25.0. To verify the effect of TKM for ERAS, we analyzed improvement of symptoms. Also, we analyzed survey of patients' satisfaction to verify the satisfaction of TKM for ERAS.
Results: Among the symptoms of pain, there was a statistically significant decrease in all types of pain on the questionnaire. Other systemic symptoms showed statistically significant improvement in all symptoms on the questionnaire. The satisfaction level questionnaires for TKM for ERAS showed a mean value of 4.37±0.63 out of 5-point scale. Especially, herbal medicine, acupuncture, and moxibustion showed high satisfaction without dissatisfaction.
Conclusions: The result has shown that TKM for ERAS after gynecological surgery is effective and the satisfaction of the patients is high. Further study on TKM for ERAS for quality of life assessment is needed.

KCI등재

저자 : 김태희 ( Tae-hee Kim ) , 이인선 ( In-seon Lee ) , 김종원 ( Jong-won Kim ) , 전수형 ( Soo-hyung Jeon ) , 지규용 ( Gyoo-yong Chi ) , 강창완 ( Chang-wan Kang )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 105-121 (17 pages)

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Objectives: It is a statistical analysis study to examine the results of CaPSPI (Diagnostic System for Climacteric and Postmenopausal Syndrome Pattern Identification), developed for objective defecation of climacteric and postmenopausal syndrome.
Methods: Total 341 people's questionnaire responses were statistically analyzed. 275 people involved in developing CaPSPI 2018 (E) and 146 people involved in 2019-2020 study of research1,3).
Results: The frequency of diagnosis for examination was the highest at liver depression, 93.8% for 320 times, the lowest at heartheat, 62.8% for 214 times. The frequency of treatment for examination was the highest at liver depression,54.3% for 185 times, and the lowest at dual deficiency of heart-spleen, 16.7% for 57 times. The diagnosis ratio was the lowest at dual deficiency of heart-spleen, 19.72%, and the highest at liver depression, 57.81%. As a result of comparing these diagnoses with the Kupperman's index, all showed significant differences. As a result of comparing these disease elements, all showed significant differences. The correlation between diagnosis and dialectic elements was found to have similar results with the korean medical pathology, and in 7 dialectics except for heartheat, the treatment version was more severe or progressing to perjury than for examination.
Conclusions: The CaPSPI shows the characteristics of korean medicine well, and it is needed to utilize the high correlative disease elements to upgrade the system.

KCI등재

저자 : 조시윤 ( Si-Yoon Cho ) , 이지연 ( Ji-yeon Lee )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 122-136 (15 pages)

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Objectives: The aim of this study is to investigate Heart Rate Variability (HRV) characteristics of patients with primary dysmenorrhea at the menstrual phase.
Methods: 7 databases (Pubmed, Cochrane library, CNKI, RISS, KISS, OASIS, ScienceON) were searched for eligible studies published before 2021 December. The studies comparing HRV between patients with primary dysmenorrhea and controls were included. A random-effects model was used to evaluate differences of HRV parameters between patients with primary dysmenorrhea and controls.
Results: 4 articles were included in this review based on inclusion and exclusion criteria. SDNN (Standard deviation of NN intervals), RMSSD (Square root of the mean squared difference of successive NN intervals), mean PR (Mean of pulse rate), LF (Low frequency), HF (High frequency), was the most frequently used as HRV parameters. RMSSD was significantly lower in patients with primary dysmenorrhea than controls. There was no statistically significant difference of other HRV parameters between patients with primary dysmenorrhea and controls.
Conclusions: This study suggests that parasympathetic activity and overall functions of autonomic nervous system might be decreased in patients with primary dysmenorrhea at the menstrual phase. In the future, well-designed clinical studies using HRV and additional meta-analysis should be conducted to obtain a wealth of information about HRV characteristics of patients with primary dysmenorrhea

KCI등재

저자 : 안혜원 ( Hye-won An ) , 조시윤 ( Si-yoon Cho ) , 윤희재 ( Hee-jae Yoon ) , 이지연 ( Ji-yeon Lee )

발행기관 : 대한한방부인과학회 간행물 : 대한한방부인과학회지 35권 3호 발행 연도 : 2022 페이지 : pp. 137-149 (13 pages)

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Objectives: The purpose of this study is to report the effect of Korean medicine treatment in a patient with Herpes Zoster (HZ) during pregnancy.
Methods: During 12 days of hospitalization, a patient was treated by Korean medicine treatment such as herbal medicine including Gami-danggui-san, acupuncture, cupping and fumigation. To evaluate the effect of treatment, we took pictures of skin lesion and symptoms were measured by Numeric Rating Scale (NRS), Short-Form McGill Pain Questionnaire (SF-MPQ) and 36 item Short Form Health Survey (SF-36).
Results: After Korean medicine treatment, most of vesicles disappeared. NRS of chief complaints such as neuralgic pain and itchness changed 7-8 to 0 and therefore, quality of life of the patient was elevated sharply.
Conclusions: This case shows that Korean medicine treatment is beneficial and safe for the patients who suffered from Herpes Zoster during pregnancy.

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