간행물

대한피부과학회> Annals of Dermatology

Annals of Dermatology update

  • : 대한피부과학회
  • : 의약학분야  >  피부과학
  • : KCI등재
  • : SCOPUS
  • : 연속간행물
  • : 격월
  • : 1013-9087
  • : 2005-3894
  • :

수록정보
수록범위 : 1권1호(1989)~34권6호(2022) |수록논문 수 : 3,098
Annals of Dermatology
34권6호(2022년 12월) 수록논문
최근 권호 논문
| | | |

KCI등재 SCOPUS

저자 : Soo Hyeon Bae , Jun Hyeong Park , Soo-hyun Kim , Sook Jung Yun , Jae Gwan Kim , Jee-bum Lee

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 401-412 (12 pages)

다운로드

(기관인증 필요)

초록보기

Background: Melatonin receptors are present in the human skin and retina. These receptors can be stimulated by light emitting diodes (LEDs) at specific wavelengths, thereby inducing cutaneous photorejuvenation. However, the underlying mechanism remains unclear.
Objective: To evaluate the influence of LEDs at specific wavelengths on melatonin membrane receptor (MT1) and cutaneous photorejuvenation via the MT1 pathway in vitro.
Methods: Normal human dermal fibroblasts (HDFs) were irradiated using LEDs at different wavelengths (410~940 nm) at a dose of 1 J/cm2. MT1 activity was evaluated after melatonin stimulation and LED irradiation. Thereafter, the expressions of collagen (COL) and matrix metalloproteinases (MMPs), with and without luzindole (MT1/2 receptor antagonist), were investigated via semi-quantitative reverse transcription polymerase chain reaction (PCR), real-time PCR, western blotting, and enzyme-linked immunosorbent assay.
Results: In HDFs, the MT1 mRNA and protein levels increased significantly in response to melatonin (dose, 50 nM) (p<0.01) and LED irradiation at 595, 630, 850, and 940 nm (p<0.01). LED irradiation up-regulated COL type I and down-regulated MMP-1. Compared to LED irradiation without luzindole, LED irradiation with luzindole produced no significant increase in COL type I mRNA and protein levels (p<0.01).
Conclusion: We found that LED irradiation induces collagen synthesis and MMP-1 inhibition in HDFs via MT1 activation. Additionally, multiple LED wavelengths (595, 630, 850, and 940 nm) stimulated MT1 in HDFs, unlike in the eyes, where only blue light induced plasma melatonin suppression. This suggests the possibility of the melatoninergic pathway in photorejuvenation.

KCI등재 SCOPUS

저자 : Ji Yeon Hong , Su Jung Park , Soo Yeon Kim , Beom Joon Kim

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 412-418 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: Treatment options for pseudogynecomastia are limited, and the demand for noninvasive breast fat reduction is increasing.
Objective: We evaluated the efficacy and safety of a cold-induced lipolysis device for treating pseudogynecomastia.
Methods: In this 16-week prospective trial, a total of 15 male patients with pseudogynecomastia were treated twice with cryolipolysis. The primary endpoint was a change in the chest circumference from baseline at posttreatment week 8. Secondary endpoints were changes in body weight, fat thickness assessed using ultrasonography, independent evaluator- and patient-rated improvement, and Simon's gynecomastia class (SGC) grading.
Results: The primary assessment, a reduction of 3.05 cm in the mean chest circumference at 8 weeks post-treatment compared to baseline, was statistically significant. The treatment effect was cumulative, with a steady decrease in chest circumference and fat thickness over the 16-week study period. The mean pain score immediately after the first session of treatment was 2.0±1.36, based on a scale of 0~10, with a score of 10 being the worst pain ever experienced. The pain decreased substantially after the end of the procedure.
Conclusion: Cryolipolysis was demonstrated to be an effective and safe option for reducing breast fat in pseudogynecomastia. Male with mild to moderate breast enlargement without skin excess can be ideal candidates.

KCI등재 SCOPUS

저자 : Sang Wook Son , Ji Hyun Lee , Jiyoung Ahn , Sung Eun Chang , Eung Ho Choi , Tae Young Han , Yong Hyun Jang , Hye One Kim , Moon-bum Kim , You Chan Kim , Hyun Chang Ko , Joo Yeon Ko , Sang Eun Lee , Yang

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 419-434 (16 pages)

다운로드

(기관인증 필요)

초록보기

Background: Data illustrating the impact of atopic dermatitis (AD) on lives of adults with AD in South Korea are limited.
Objective: To assess the AD disease severity and its impact on quality of life (QoL) in patients with AD from South Korea.
Methods: Patients with AD utilizing the specialist dermatology services of major hospitals in South Korea were assessed for disease severity using Eczema Area and Severity Index (EASI) score, for QoL using Dermatology Life Quality Index (DLQI) (for QoL), and for comorbidities and treatment experience via retrospective review of 12-month medical records. Clinical and sociodemographic characteristics were also measured.
Results: Of the 1,163 patients, 695 (59.8%) were men (mean age [years]±standard deviation: 31.6±12.1). Overall, 52.9% (n=615) patients had moderate-to-severe disease (EASI>7). The QoL of 72.3% (n=840) patients was affected moderately-to-severely (DLQI score: 6~30). Systemic immunosuppressants were used ≥1 over past 12 months in 51.9% (n=603) patients, and the most commonly used were cyclosporines (45.7%, n=531) and systemic corticosteroids (40.5%, n=471). Approximately, 10.8% (n=126) patients consulted or received treatment for AD-related eye problem. Of these, 40% (n=50) patients reported poor, very poor, or completely blind status; approximately, 16.7% patients (n=192) reported having depression or anxiety; and 35.5% (n=410) reported suicidal ideation or suicidal attempt.
Conclusion: A large proportion of patients had moderate-to-severe AD, a compromised QoL, and ocular or mental health comorbidities, indicating a high disease burden despite systemic treatment. These findings highlight the importance of a holistic approach for the evaluation and treatment of patients with AD.

KCI등재 SCOPUS

저자 : Yujin Han , Yu Ri Woo , Hei Sung Kim , Jeong Deuk Lee , Sookhee Choi , Jeesuk Yu , Sang Hyun Cho

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 431-442 (12 pages)

다운로드

(기관인증 필요)

초록보기

Background: Avoiding causative allergens is important for controlling the clinical course of allergic diseases. Allergen sensitization is influenced by many factors including the environment and lifestyle. The socioeconomic development, climate, and lifestyle changes have increased the prevalence of allergic diseases worldwide. However, there is little information about changes in the trend of the common allergens over time.
Objective: This study was aimed at identifying the trends of the common allergens in Korea over a 10-year period based on the results of the multiple allergosorbent test chemilumines-cent assay (MAST-CLA).
Methods: We retrospectively reviewed the medical records of 5,760 patients aged ≥18 years who visited the Dermatology Department at a tertiary hospital over a period of 10 years. The serum total immunoglobulin (Ig) E and specific IgE levels to 41 allergens were determined using MAST-CLA, along with the clinical diagnosis, duration of illness, white blood cell count and eosinophil percentage.
Results: Dermatophagoides farinae, Dermatophagoides pteronyssinus , and house dust were the most prevalent allergens during the 10 years period, but the percentage of higher class responses has decreased in recent years. The number of patients sensitized to house dust (p<0.001), dogs (p=0.005), and cats (p<0.001) increased while that of patients sensitized to cockroaches (p<0.001) and storage mites (p<0.001) decreased over time. There were no significant changes in the total number of sensitizing allergens over time.
Conclusion: The common allergens have changed over time. Based on the findings of this study, physicians and patients should consider changing their strategies for disease prevention and management.

KCI등재 SCOPUS

저자 : Dong Min Shin , Jongeun Lee , Hyungrye Noh , Donghwi Jang , Se Jin Oh , Ji Hye Park , Jong Hee Lee

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 442-450 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background: Intradermal injection of botulinum toxin A (BTXA) is used for cosmetic purposes without strong evidence for clinical use, as opposed to intramuscular injection.
Objective: To evaluate the efficacy and safety of intradermal injection of incobotulinum toxin A (iBTXA) in the cheeks.
Methods: We conducted a study with 18 volunteers who received intradermal injection of iBTXA into one cheek and normal saline into the contralateral side as a control. Volunteers visited the clinic at weeks 2, 4, 8, and 12 after injection. At each visit, pores and wrinkles were evaluated by a facial analyzer, sebum secretion by a sebumeter, skin texture by both volunteers and clinicians, and wrinkles of the nasolabial fold were graded with photographic reviews.
Results: There were no significant effects on the wrinkles of the infraorbital area and sebum secretion. However, there were significant improvements in the wrinkles of the nasolabial fold and skin texture on the iBTXA injected side. The effects on the wrinkles of the nasolabial fold lasted 12 weeks, and those on skin texture lasted 8 weeks. Improvement in the pore size was observed only at week 2. No serious adverse events were reported except one volunteer who complained of facial palsy after the injection of 30 units of iBTXA in one cheek. However, injection of 20 units of iBTXA in one cheek was not associated with any adverse events.
Conclusion: Intradermal injection of iBTXA, could provide clinical benefits for skin texture and wrinkles overcoming the skin prick effect without obvious side effects.

KCI등재 SCOPUS

저자 : Jin Soo Kim , Byeong Hak Seo , Doo Rae Cha , Ho Seok Suh , Yu Sung Choi

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 451-460 (10 pages)

다운로드

(기관인증 필요)

초록보기

Background: Rosacea is a chronic inflammatory disease which requires treatment to maintain remission.
Objective: Recently, the effect of Demodex mites in recurrence of rosacea has been described. Although there is limited data, previous reports have suggested that oral metronidazole demonstrated efficacy in treatment of rosacea.
Methods: Fifty-eight Korean patients with rosacea who received treatment with oral minocycline (50 mg twice daily) only or with two-week of oral metronidazole (250 mg thrice daily) were evaluated retrospectively. Their responses were evaluated by Investigator's Global Assessment (IGA), Clinician's Erythema Assessment (CEA), and patient's Global Assessment. The recurrence rate and odds ratio of risk factors for recurrence were also estimated.
Results: The combination treatment group reported earlier clinical improvement and lower mean IGA and CEA than the monotherapy group. Approximately 48% of patients with combination treatment did not show relapse within 24 weeks, which is significantly higher than that in the monotherapy group (p=0.042).
Conclusion: Add-on therapy of oral metronidazole appeared to be a significant protective factor for recurrence of rosacea (p<0.05). This study suggests that oral metronidazole can be added to oral minocycline to reduce relapses in rosacea patients with tolerable safety.

KCI등재 SCOPUS

저자 : Ji Su Lee , Seon Mi Lee , Hyung Seok Son , Yi Na Yoon , Jung Eun Shin , Woo Jun Sul , Da Ae Yu , Yong Beom Choe , Yang Won Lee

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 461-471 (11 pages)

다운로드

(기관인증 필요)

초록보기

Background: Recently, microbiome research has been actively conducted for various skin areas. However, no study has yet compared the microbiome of bacteria and fungi in the ear canal of healthy individuals and patients with chronic otitis externa in Korea.
Objective: This study aimed to investigate the difference in the distribution of fungal and bacterial microbial communities in ear canal samples of healthy individuals and patients with chronic otitis externa.
Methods: In 24 patients with bilateral chronic otitis externa and 24 healthy controls, cotton swabs were used to obtain samples from the bilateral ear canal. To characterize the fungal and bacterial communities, we sequenced and analyzed the 16S rRNA V4-V5 and ITS1 regions using Quantitative Insights into Microbial Ecology 2, respectively.
Results: The alpha diversity analysis for bacteria and fungi confirmed that both richness and evenness decreased in the patient group. The beta diversity analysis for bacteria confirmed that these parameters differed between the control and patient groups. The beta diversity analysis for fungi showed no difference between the groups.
Conclusion: We observed different skin microbiomes in the patients with chronic otitis externa compared with those in the healthy individuals.

KCI등재 SCOPUS

저자 : Taehwa Kim , Do Hyung Kim , Seung Eun Lee , Min-young Yang , Yun Seong Kim

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 472-474 (3 pages)

다운로드

(기관인증 필요)

초록보기

Recently, some cases of basal cell carcinoma (BCC) with lung metastasis have been reported, but those involving simultaneous tracheal, bronchial, and lung metastases have been rarely reported. Here, we have reported a very unusual case of BCC with metastasis, presenting with lung nodules and endobronchial lesions after two metastasectomies. Since BCC is a slow-growing cancer that rarely metastasizes to distant organs, tumor stage workup including radiological imaging has not been routinely performed in clinical practice. This case showed that BCC can metastasize to the lung, although the currently reported metastasis rate of BCC is extremely low.

KCI등재 SCOPUS

저자 : Joon Woo Jung , Ye Ji Jang , Eun Hye Hong , Kwang Ho Kim , Kwang Joong Kim , Eun Joo Park

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 475-477 (3 pages)

다운로드

(기관인증 필요)

초록보기

Herpes zoster is caused by the varicella-zoster virus, which becomes latent in ganglia after primary infection. When the varicella-zoster virus reactivates on the cranial nerve, the patient can suffer from cranial nerve palsy, pain, and skin lesions on the head and neck area. A 57-year-old immunocompetent male presented with dysphagia lasting 10 days. Computed tomography and other neurological findings were normal. However, laryngoscopy showed right vocal cord paralysis, which might be the reason for dysphagia in this patient. There was a grouped crusted lesion on the right posterior auricular area that appeared 5 days after the dysphagia. After famciclovir and prednisolone combination therapy, the patient was cured with no sequelae. This is a rare case of herpes zoster in an immunocompetent patient who presented with dysphagia. In addition, it was difficult to make an accurate diagnosis because his skin lesion appeared several days after dysphagia.

KCI등재 SCOPUS

저자 : Ko Eun Kim , Jae Yeong Jeong , Tae Jun Park , Il-hwan Kim

발행기관 : 대한피부과학회 간행물 : Annals of Dermatology 34권 6호 발행 연도 : 2022 페이지 : pp. 478-481 (4 pages)

다운로드

(기관인증 필요)

초록보기

A 78-year-old male presented with an asymptomatic pinkish multi-nodular mass on his frontal scalp. The lesion had recurred twice after incomplete surgical excision. Initial punch biopsy was diagnosed with cylindroma. He revisited after one year with exophytic enlargement of the mass, and two staged Mohs micrographic surgery identified well-differentiated malignant cylindroma. Histopathology in the lower dermis and periosteal layer showed atypical cells with mitosis and hyperchromatic nucleoli with increased Ki-67 index of 10% to 30%. The postoperative wound was successfully treated with negative wound pressure therapy (NPWT) and secondary intentional healing. We report this case showing malignant transformation of solitary cylindroma, and good result for secondary intention healing using NPWT for postoperative defect.

12
권호별 보기

내가 찾은 최근 검색어

최근 열람 자료

맞춤 논문

보관함

내 보관함
공유한 보관함

1:1문의

닫기