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대한소화기학회지 update

The Korean Journal of Gastroenterology

  • : 대한소화기학회
  • : 의약학분야  >  내과학
  • : KCI등재
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  • : 연속간행물
  • : 월간
  • : 1598-9992
  • : 2233-6869
  • : 대한소화기병학회잡지(~1989) → 대한소화기병학회지(1990~) → 대한소화기학회지(1995~)

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수록범위 : 1권1호(1968)~79권6호(2022) |수록논문 수 : 5,834
대한소화기학회지
79권6호(2022년 06월) 수록논문
최근 권호 논문
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KCI등재

1대장 게실 질환의 진단 및 치료

저자 : 김유선 ( You Sun Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 233-243 (11 pages)

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Colonic diverticulosis is one of the most common conditions of the digestive system and patients generally remain asymptomatic. However, about 20% of patients develop symptomatic diverticular disease such as acute diverticulitis or diverticular hemorrhage, and these have become a huge burden on healthcare systems worldwide. Recent understanding of the pathophysiology of diverticulosis and diverticular disease suggests the role of multiple factors including genetic and environment. Based on this understanding, a preventive strategy to reduce the risk factors of diverticulosis and diverticular disease is highly recommended. The diagnosis of the acute diverticulitis relies on imaging modalities such as an abdominal-pelvic CT scan together with symptoms and signs. Treatment of diverticular disease should be individualized and include modification of lifestyle, use of antibiotics, and surgery. Recent guidelines recommend pursuing less aggressive treatment for patients with acute diverticulitis. This review will provide an overview of both the existing and evolving understanding regarding colonic diverticulosis and diverticular disease and can help clinicians in the management of their patients with diverticular disease. (Korean J Gastroenterol 2022;79:233-243)

KCI등재

2최근 10년간 국내 80세 이상 노인에서 소화기 질환의 변화: 다기관 단면 연구

저자 : 우서경 ( Seo Kyung Woo ) , 김신승 ( Shin Seung Kim ) , 정우철 ( Woo Chul Chung ) , 김준성 ( Joon Sung Kim ) , 김병욱 ( Byung-wook Kim ) , 최현호 ( Hyun Ho Choi ) , 김성수 ( Sung Soo Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 244-251 (8 pages)

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목적: 전 세계적으로 80세 이상 인구는 기대수명의 증가로 인해 빠르게 증가하고 있다. 우리나라는 이미 고령화 사회에 진입하였으며, 2025년에는 후기 고령화 사회로 진입할 것으로 예상한다. 본 연구의 목적은 우리나라에서 최근 10년 동안 80세 이상 인구의 위장 질환 변화를 분석하는 것이다.
대상 및 방법: 서울 주변의 경기 권역의 남부, 서부, 북부에 위치한 수원 성빈센트병원, 인천성모병원, 의정부성모병원의 상급 종합병원의 소화기내과에 입원한 환자들의 의무기록을 후향적으로 조사하였으며, 2009년과 2019년에 반복한 단면연구를 비교하였다.
결과: 80세 이상 입원 환자는 2009년 549명(9.0%)에서 2019년 1,073명(14.4%)으로 증가하였다(p<0.01). 입원 사망률은 유의한 차이가 없었지만(p=0.25), 동반된 합병증 및 입원 기간은 증가하였다(7.2±7.8일 vs. 8.1±8.2일, p=0.03). 상부위장관 출혈 및 출혈 연관 약제의 사용은 증가하였다(p<0.01). 하부위장관 질환의 비율은 감소하였는데(p<0.01), 이는 시술 관련입원이 감소(p<0.01)하였기 때문이다. 췌장담도 질환도 증가하였고(p<0.01), 수술이나 시술을 할 수 없는 사례는 감소하였다(p=0.04).
결론: 고령화로 노인 환자수가 증가하고 있으며 최근 10년간 우리나라 80세 이상 인구의 소화기 질환이 변화하고 있음을 확인하였다. 앞으로 이러한 의료 환경에 대비하여 다양한 논의와 준비가 필요할 것으로 보인다.


Background/Aims: Globally, the population aged 80 years or older is growing faster due to the rising life expectancy. Korea has already entered into an advanced aged society, and a post-aged society is expected in 2025. This study evaluated the patterns of gastrointestinal disease in the population aged 80 years or older during the recent decade in Korea.
Method: This study retrospectively reviewed the medical records of patients admitted to the gastrointestinal department of Suwon St. Vincent's hospital, Incheon St. Mary's hospital, and Uijeongbu St. Mary's Hospital ― general hospitals of Seoul-Gyeonggi province in Korea. It was a repeated cross-sectional study in 2009 and 2019.
Results: The number of admitted patients aged 80 years or older increased from 549 (9.0%) in 2009 to 1,073 (14.4%) in 2019 (p<0.01). As for the in-hospital mortality, there was no significant difference (p=0.25). On the other hand, the combined morbidities increased, and the duration of admission also increased (7.2±7.8 days vs. 8.1±8.2 days, p=0.03). The number of upper gastrointestinal hemorrhage and patients who are bleeding associated with drugs users increased (p<0.01). The proportion of lower gastrointestinal disease decreased (p<0.01) because of the decrease in procedure-related admissions (p<0.01). The number of those with pancreaticobiliary tract disease increased markedly (p<0.01), and the rate of cases that could not perform the procedure decreased (p=0.04).
Conclusion: The patterns of gastrointestinal disease in the population aged 80 years or older have changed in the recent decade in Korea. Hence, more preparation for this medical environment is needed. (Korean J Gastroenterol 2022;79:244-251)

KCI등재

3정위체부방사선치료를 시행받은 간세포암종 환자에서 호중구-림프구, 혈소판-림프구 비율에 대한 연구

저자 : 박영희 ( Younghee Park ) , 장아람 ( Ah Ram Chang )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 252-259 (8 pages)

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Purpose: To investigate the prognostic value of the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with hepatocellular carcinoma (HCC) treated with stereotactic body radiotherapy (SBRT).
Methods: The medical records of HCC patients treated with SBRT between 2008 and 2019 were reviewed retrospectively. The NLR and PLR were calculated from the serum complete blood count before and after SBRT, and the prognostic values of the NLR and PLR for the treatment outcomes were evaluated.
Results: Thirty-nine patients with 49 HCC lesions were included. After a median follow-up of 26.8 months (range, 8.4-80.0 months), three-year local control, overall survival (OS), and progression-free survival (PFS) rate were 97.4%, 78.3%, and 35.2%, respectively. Both NLR and PLR increased significantly after SBRT and decreased slowly to the pre-SBRT value at 6 months. Univariable analysis showed that gross tumor volume (GTV) >14 cc, post-SBRT PLR >90, and PLR change >30 were associated with a poorer OS (p=0.002, p=0.011, and p=0.001, respectively), and the PLR change was significant in multivariable analysis (hazard ratio [HR], 10.09; 95% CI, 1.15-88.40; p=0.037). For PFS, GTV >14 cc, post-SBRT NLR >2.5 and post-SBRT PLR >90 were predictive of a poorer PFS in univariable analysis (p=0.011, p=0.004 and p=0.041, respectively) and only post-SBRT NLR >2.5 remained significant in multivariable analysis (HR, 2.44; 95% CI, 1.03-5.76; p=0.042, respectively).
Conclusions: The NLR and PLR increased transiently after SBRT, and the post-SBRT NLR and PLR were associated with the clinical outcomes of HCC patients. (Korean J Gastroenterol 2022;79:252-259)

KCI등재

4위출구폐쇄로 삽입한 금속스텐트의 기능부전 환자에서의 초음파 내시경 유도하 위공장문합술

저자 : 김병선 ( Byung Sun Kim ) , 양성열 ( Sung Yeol Yang ) , 이원동 ( Won Dong Lee ) , 송재선 ( Jae Sun Song ) , 양민아 ( Min A Yang ) , 정금모 ( Gum Mo Jung ) , 조진웅 ( Jin Woong Cho ) , 김지웅 ( Ji Woong Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 260-264 (5 pages)

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A 52-year-old woman with a gastric outlet obstruction (GOO) caused by pyloric cancer underwent pyloric endoscopic self-expandable metal stent (SEMS) insertion. She presented with abdominal distension 40 days later. The SEMS was dysfunctional, and endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) was performed using an endoscopic nasobiliary drainage tube. A 16 mm×31 mm Niti-S™ HOT SPAXUS™ (TaeWoong Medical, Gimpo, Korea) was inserted successfully between the stomach and the adjacent jejunum. After the procedure, the patient had a good oral intake for more than seven months. GOO is a mechanical obstructive condition caused by various benign and malignant conditions. Traditionally, surgical GJ and SEMS insertion have been used to treat GOOs. EUS-GJ is a feasible treatment option for patients with GOO and a pyloric metal stent dysfunction. (Korean J Gastroenterol 2022;79:260-264)

KCI등재

5제1형 신경섬유종증에서 발생한 위 악성 말초신경초종양

저자 : 황현승 ( Hyun Seung Hwang ) , 정윤진 ( Yun Jin Jeong ) , 남경한 ( Kyung Han Nam ) , 오성진 ( Sung Jin Oh ) , 박용은 ( Yong Eun Park )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 265-269 (5 pages)

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Gastric malignant peripheral nerve sheath tumors (MPNSTs) are extremely rare spindle cell sarcomas that arise within the peripheral nerves of the gastrointestinal tract. MPNST can present as a mass that may or may not be accompanied by obstruction or bleeding. Type 1 neurofibromatosis (NF) is an autosomal dominant genetic disorder with an incidence of 1 in 2,500-3,000. Plexiform neurofibromas in Type 1 NF can undergo a malignant transformation to MPNSTs. Approximately half of the incidence of MPNST is associated with the NF-1 gene. MPNST behaves aggressively, and radical excisional surgery is important for treatment. Recurrence and metastasis are significant, even after a radical excision. Despite multidisciplinary treatment, the five-year survival rate is only 30-50%. This paper reports the case of a 47-year-old man with Type 1 NF who presented with hemorrhage of a gastric subepithelial lesion. He underwent surgery under the suspicion of a gastrointestinal stromal tumor, but it was diagnosed as MPNST after confirming the histopathological appearance and immunohistochemical profiles. In addition, the large mass invaded the spleen and diaphragm. Radical surgery was performed, and additional chemotherapy was administered. This paper reports the experience of a patient with NF 1 with advanced MPNST discovered due to a subepithelial lesion. (Korean J Gastroenterol 2022;79:265-269)

KCI등재

6강직척추염에 동반된 원발담즙담관염

저자 : 홍영미 ( Young Mi Hong ) , 윤기태 ( Ki Tae Yoon ) , 조몽 ( Mong Cho )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 270-273 (4 pages)

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Primary biliary cholangitis is a chronic inflammatory autoimmune liver disease that is characterized by a positive antimitochondrial antibodies test and progressive destruction of the small intrahepatic bile duct. Ankylosing spondylitis is a chronic, systemic, inflammatory disease of the spine and the sacroiliac joints. The association between these two is very low. This paper reports a rare case who had ankylosing spondylitis and developed primary biliary cholangitis. (Korean J Gastroenterol 2022;79:270-273)

KCI등재

7신농양을 동반한 간농양 환자에서 뒤늦게 발견된 간세포암종

저자 : 조수현 ( Su Hyeon Cho ) , 박찬 ( Chan Park ) , 윤재현 ( Jae Hyun Yoon )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 274-277 (4 pages)

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8위장관 마이크로바이옴 분석을 이용한 위암 검진이 가능할 것인가?

저자 : 양효준 ( Hyo-joon Yang )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 79권 6호 발행 연도 : 2022 페이지 : pp. 278-280 (3 pages)

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