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대한소화기학회지 update

The Korean Journal of Gastroenterology

  • : 대한소화기학회
  • : 의약학분야  >  내과학
  • : KCI등재
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  • : 연속간행물
  • : 월간
  • : 1598-9992
  • : 2233-6869
  • : 대한소화기병학회잡지(~1989) → 대한소화기병학회지(1990~) → 대한소화기학회지(1995~)

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수록범위 : 1권1호(1968)~81권0호(2023) |수록논문 수 : 5,891
대한소화기학회지
81권0호(2023년) 수록논문
최근 권호 논문
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KCI등재

저자 : 이한희 ( Han Hee Lee ) , 김진수 ( Jin Su Kim ) , 궁현정 ( Hyeon Jeong Goong ) , 이신희 ( Shin Hee Lee ) , 오은혜 ( Eun Hye Oh ) , 박지혜 ( Jihye Park ) , 김민철 ( Min Cheol Kim ) , 남광우 ( Kwangwoo Nam ) , 양영주 ( Young Joo Yang ) , 김태준 ( Tae Jun Kim ) , 남승주 ( Seung-joo Nam ) , 문희

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 1-16 (16 pages)

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The introduction of device-assisted enteroscopy (DAE) in the beginning of the 21st century has revolutionized the diagnosis and treatment of diseases of the small intestine. In contrast to capsule endoscopy, the other main diagnostic modality of small bowel diseases, DAE has the unique advantages of allowing the observation of the region of interest in detail and enabling tissue acquisition and therapeutic intervention. As DAE becomes an essential procedure in daily clinical practice, there is an increasing need for correct guidelines on when and how it is to be performed and what technical factors should be taken into consideration. In response to these needs, the Korean Association for the Study of Intestinal Diseases has developed an expert consensus statement on the performance of DAE by reviewing current evidence. This expert consensus statement particularly focuses on the indications, choice of insertion route, therapeutic intervention, complications, and relevant technical points. (Korean J Gastroenterol 2023;81:1-16)

KCI등재

저자 : 김진동 ( Jin Dong Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 17-28 (12 pages)

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Acute liver failure (ALF) is a rare disease condition with a dynamic clinical course and catastrophic outcomes. Several etiologies are involved in ALF. Hepatitis A and B infections and indiscriminate use of untested herbs or supplemental agents are the most common causes of ALF in Korea. Noninvasive neurological monitoring tools have been used in patients with ALF in recent times. Ongoing improvements in intensive care, including continuous renal replacement therapy, therapeutic plasma exchange, vasopressor, and extracorporeal membrane oxygenation, have reduced the mortality rate of patients with ALF. However, liver transplantation is still the most effective treatment for patients with intractable ALF. There is a need for further research in the areas of better prognostication and precise selection of patients for emergency transplantation. (Korean J Gastroenterol 2023;81:17-28)

KCI등재

저자 : 정하나 ( Hana Jung ) , 신다윗 ( Da Wit Shin ) , 정대영 ( Dae Young Cheung ) , 이한희 ( Han Hee Lee ) , 김진일 ( Jin Il Kim ) , 박수헌 ( Soo-heon Park ) , 김태정 ( Tae Jung Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 29-35 (7 pages)

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목적: 위 점막연관림프조직 림프종(위 MALT 림프종)은 헬리코박터 파일로리 감염과 관련이 있으며 일부에서는 t(11:18) 돌연변이가 동반되어 있다.
대상 및 방법: 전자의무기록 검색을 이용하여 2004년 1월부터 2020년 12월까지 가톨릭대학교 여의도성모병원에서 위 MALT 림프종으로 진단받은 환자를 연속적으로 등록하여 후향 분석하였다.
결과: 의무기록에서 찾은 77명의 위 MALT 림프종 환자 중 기록이 완결된 65명을 대상으로 분석하였다. 헬리코박터 파일로리는 66.2% (43/65)에서 감염 양성이었다. T(11:18) 돌연변이에 대한 유전자 검사는 41명에서 시행되었으며 31.7% (13/41)에서 동반되어 있었다. T(11:18) 돌연변이가 동반된 경우 제균 치료 후 관해에 도달한 경우는 23.1% (3/13)으로 t(11:18)이 동반되지 않았던 75% (21/28)에 비해 유의하게 낮은 수준이었다(p-value=0.009). 특히, 헬리코박터 음성이면서 t(11:18)가 동반된 경우 83.3% (5/6)에서 관해 도달을 위해 방사선 치료가 필요하였고 16.7% (1/6)에서만 제균 치료만으로 관해 도달이 가능하였다. 다만, 분석 대상이 적어 통계적 유의성을 확인할 수는 없었다.
결론: 헬리코박터 음성과 t(11:18)의 존재는 항생제 치료 실패의 위험 인자였다.


Background/Aims: The gastric extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (gastric MALT lymphoma) are mostly related to Helicobacter pylori infections. However, chromosomal aberration involving translocation t(11;18) is also frequently reported in these patients.
Methods: The study was a retrospective review and analysis of electronic medical records to assess the factors which affect complete remission (CR) in patients with gastric MALT lymphoma. Based on the medical records, subjects with gastric MALT lymphoma were enrolled consecutively from January 2004 to December 2021.
Results: Among the 77 subjects who were found with gastric MALT lymphoma in the database, 65 cases with complete records were analyzed. Of these, 66.2% (43/65) were H. pylori positive. Genetic analyses for t(11:18) were done on 41 subjects. The t(11:18) chromosomal translocation with MALT1:BIRC3 fusion was found in 31.7% (13/41) of the subjects. With H. pylori eradication therapy, 75% (21/28) of the subjects without t(11:18) achieved CR. However, only 23.1% (3/13) subjects with t(11:18) could achieve CR (p-value= 0.009). In the H. pylori-positive group, 85.7% (18/21) subjects without t(11:18) achieved CR with eradication therapy, but 71.4% (5/7) subjects with t(11:18) failed to achieve CR (p-value=0.004). In the H. pylori-negative group, 42.3% (3/7) of the subjects without t(11:18) achieved CR with eradication therapy. However, 83.3% (5/6) of H. pylori-negative subjects with t(11:18) failed to achieve CR with eradication therapy and needed additional radiotherapy (p-value=0.396).
Conclusions: H. pylori negativity and the presence of t(11:18) were both risk factors for failure to achieve CR with H. pylori eradication therapy as the first line of treatment. (Korean J Gastroenterol 2023;81:29-35)

KCI등재

저자 : 김소영 ( Soyoung Kim ) , 소훈섭 ( Hoonsub So ) , 정석원 ( Seok Won Jung ) , 방성조 ( Sung Jo Bang )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 36-39 (4 pages)

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The guidewire is an essential accessory in ERCP. Although rare, guidewires can cause complications, such as subcapsular hepatic hematoma, perforation, knotting, fracture, and impaction, during ERCP. This report describes a guidewire impaction during the endoscopic treatment of a patient with symptomatic chronic pancreatitis. The methods used to treat guidewire impaction are not well known. In the present case, the impacted guidewire was retrieved by inserting another guidewire and dilating the space adjacent to it. Endoscopists should check for the free movement of the guidewire before stent deployment. Additionally, it is important to ask for help from experienced senior staff to overcome any challenges during the procedure. In conclusion, endoscopists should be aware of the possibility of a guidewire impaction during ERCP. (Korean J Gastroenterol 2023;81:36-39)

KCI등재

저자 : Raman K. Gupta , Vishal K. Chorasiya , Vivek Vij , Manav Wadhawan , Ajay Kumar , Nalini Bansal

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 40-45 (6 pages)

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An undifferentiated carcinoma (UC) of the gall bladder behaves aggressively and has a grave prognosis. Small cell type undifferentiated carcinoma of the gall bladder is a rare variant. This paper reports a case of UC of gall bladder with PAS-positive diastase- resistant eosinophilic hyaline globules present as liver mass (on imaging) in a male patient. The microscopic findings of the liver and gall bladder after a right tri-segmentectomy showed an un-differentiated malignant neoplasm composed of cells with round to oval nuclei, prominent nucleoli, and scanty neoplasm. No definite cell pattern was identified with these neoplastic cells. A section from the gall bladder revealed a tumor arising from the lining epithelium and infiltrating through the muscularis. This tumor was infiltrating the adherent liver tissue directly and forming a mass of undifferentiated malignant cells. The focal area within the tumor mass showed the presence of PAS-positive, diastase-resistant, eosinophilic hyaline globules within the neoplastic cells. The immunohistochemistry test was diffusely positive for perinuclear anti-neutrophil cytoplasmic antibodies and negative for chromogranin, vimentin, Desmin, alpha-fetoprotein, leukocyte common antigen, CD34, and bcl2. When the clinical and radiological data are inconclusive, careful analysis of the histological and immunophenotypic features is needed to make the final diagnosis of UC of the gall bladder. The biological behavior and prognosis of this tumor remain unclear because of its rarity. Further studies will be needed to understand the characteristics of this deadly tumor and to establish an effective therapy for it. (Korean J Gastroenterol 2023;81:40-45)

KCI등재

저자 : Ana Catarina Carvalho , Ricardo Cardoso , Francisco Pires , Sofia Ventura , Francisco Portela , Paula Ministro , Américo Silva

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 46-51 (6 pages)

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Endometriosis is a relatively common gynecological condition in women of reproductive age. The rectosigmoid region is the most commonly affected segment when the gastrointestinal tract is involved. A differential diagnosis of colorectal neoplasia is difficult because of the similar clinical, endoscopic, and radiology findings. A 42-year-old female presented with abdominal distention and was subsequently diagnosed with a large bowel obstruction in the rectum. A temporary colostomy was performed, and endoscopy revealed a rectal mass obstructing the rectum. The biopsy showed normal mucosa, and it was difficult to exclude rectal malignancies even after the imaging workup. Endoscopic ultrasound demonstrated a hypoechoic lesion below the rectal mucosa, and fine needle aspiration confirmed the diagnosis of bowel endometriosis. Bowel endometriosis is a challenging diagnosis. Endoscopic ultrasound- guided fine-needle aspiration is useful for acquiring adequate samples for histological confirmation and a definitive diagnosis of bowel endometriosis. (Korean J Gastroenterol 2023;81:46-51)

KCI등재

저자 : 김준성 ( Joon Sung Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 52-54 (3 pages)

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KCI등재

저자 : 문성훈 ( Sung-hoon Moon )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 81권 0호 발행 연도 : 2023 페이지 : pp. 55-57 (3 pages)

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