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대한소화기학회지 update

The Korean Journal of Gastroenterology

  • : 대한소화기학회
  • : 의약학분야  >  내과학
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  • : 월간
  • : 1598-9992
  • : 2233-6869
  • : 대한소화기병학회잡지(~1989) → 대한소화기병학회지(1990~) → 대한소화기학회지(1995~)

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수록범위 : 1권1호(1968)~77권6호(2021) |수록논문 수 : 5,724
대한소화기학회지
77권6호(2021년 06월) 수록논문
최근 권호 논문
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KCI등재

1의료감정의 원칙과 오류: 소화기 사례를 중심으로

저자 : 염호기 ( Ho-Kee Yum )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 263-266 (4 pages)

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Medical appraisal has emerged as a medico-social problem. There are more medical appraisal errors than expected. Physicians are trained in the process of scientific thinking, and then can make a medical appraisal error. Medical appraisal requires both legal knowledge and medical experience. Medical appraisal is neither commentary nor advice for the best ideal medicine. The ideal medical practice described in textbooks and the implementation of the guidelines are different from the medical reality. Medical appraisal should reflect the real-time changing medical field. Medical appraisal experts must consider the level of medical care at the time the incident occurred, the facility, region, environment of the medical institution, and the patient's underlying disease, sequelae, and complications. Since the medical appraisal doctor conducts a retrospective analysis with all the data and time to review, it should be kept in mind that the medical appraisal may differ from the judgment of the actual medical field. Medicine is an evolving but limited science because it is the youngest science. For the fairness of medical appraisal, the medical professionalism and appraisal education of medical appraisers are essential. The Korean Medical Practice Review Authority was established in 2019 led by the Korean Medical Association. The appraisal education program was implemented to strengthen the expertise of appraisers and to develop appraisal skills. The medical field, especially gastroenterology, is the most common subject of medical appraisal. The principles and errors of medical appraisal were reviewed by focusing on the gastroenterology appraisal cases. (Korean J Gastroenterol 2021;77:263-266)

KCI등재

2연구 수행 중 연구윤리

저자 : 이인재 ( In Jae Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 267-276 (10 pages)

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Compliance with research ethics is critical to the responsible conduct of research required by researchers. Research ethics means the rules and norms that researchers need to know and practice in the process of conducting their research. Therefore, it is important for researchers to accurately understand the specific contents of research ethics required at each stage of the research process. The paper explored the meaning and values of responsible conduct of research that researchers should pursue, and discussed what responsibilities researchers need to know and the specific roles they need to act on. (Korean J Gastroenterol 2021;77:267-276)

KCI등재

3중추신경계 매개 복통 증후군

저자 : 김희진 ( Hee Jin Kim ) , 김현진 ( Hyun Jin Kim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 277-284 (8 pages)

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Centrally mediated abdominal pain syndrome (CAPS), known as functional abdominal pain syndrome in the Rome III criteria of functional gastrointestinal diseases, has a reported population prevalence of between 0.5% and 2.1%, with a female preponderance. The pathogenesis of CAPS has not been completely established, and various studies are being conducted. On the other hand, central nervous system sensitization with disinhibition of the pain signaling pathways appears to play a more important role than the up-regulation of peripheral afferent neuronal excitability. The diagnosis of CAPS is based on the Rome IV criteria (2016) and is established around the gastrointestinal symptoms combination. Various new treatment trials and effective patient-physician relationships showed progressive results. (Korean J Gastroenterol 2021;77:277-284)

KCI등재

4장기간 경구 항바이러스제 치료를 시행받은 만성 B형간염 환자에서 HBeAg 상태 및 약물 종류에 따른 HBsAg 정량값의 변화 비교

저자 : 나종화 ( Jong Hwa Na ) , 김정한 ( Jeong Han Kim ) , 최원혁 ( Won Hyeok Choe ) , 권소영 ( So Young Kwon ) , 유병철 ( Byung Chul Yoo )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 285-293 (9 pages)

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Background/Aims: The HBsAg levels have been used to monitor the chronic hepatitis B (CHB) treatment response to antiviral therapy. On the other hand, it is unclear if the HBsAg quantification levels at each treatment point differ according to the HBeAg status and drug in CHB patients. This study compared the changes in HBsAg in CHB patients according to the HBeAg status and treatment drugs.
Methods: CHB patients with at least 1 year of follow-up treatment with one drug, either entecavir (ETV) or tenofovir (TDF), were enrolled in this study. The mean HBsAg levels were measured annually for up to 6 years. A linear mixed model was used to compare the HBsAg quantification levels during the follow-up period. An independent samples t-test was used to analyze the differences in the HBsAg quantification levels at each treatment time point.
Results: Ninety-seven patients were enrolled in this study; 59 among them were HBeAg-positive. Two patients in the TDF group achieved HBsAg seroconversion. The HBsAg level decreased during the follow-up in the ETV and TDF groups. The HBsAg level was lower in the TDF group than the ETV group during the follow-up. On the other hand, subgroup analysis showed that this trend was the same only in the HBeAg-negative patients, not in the HBeAg-positive patients. In the HBeAg-negative patients, HBsAg level in the TDF group was significantly lower than that in the ETV group at 36, 48, and 72 months. The change in HBsAg level from the baseline increased at a decreasing rate during the follow-up in both groups. Furthermore, the change in the HBsAg level in the TDF group was significantly larger than that of the ETV group at 36 months in the HBeAg-negative patients.
Conclusions: Although TDF might be more efficient than ETV in reducing the HBsAg level in HBeAg-negative patients in a few years, HBsAg seroconversion occurred very rarely. A further large-scale, long-term study will be needed to confirm the antiviral effects on the HBsAg level. (Korean J Gastroenterol 2021;77:285-293)

KCI등재

5파국적 항인지질항체증후군과 관련된 소장의 괴사 1예

저자 : 이현애 ( Hyun Ae Lee ) , 김성은 ( Seong-eun Kim ) , 정도영 ( Do Woung Jung ) , 변주란 ( Ju Ran Byeon ) , 최아름 ( A Reum Choe ) , 태정현 ( Chung Hyun Tae ) , 문창모 ( Chang Mo Moon ) , 정혜경 ( Hye Kyung Jung ) , 심기남 ( Ki Nam Shim ) , 정성애 ( Sung Ae Jung )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 294-299 (6 pages)

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Catastrophic antiphospholipid syndrome is a highly fatal condition characterized by widespread thromboembolism subsequent to a triggering factor (e.g., infection, trauma, and neoplasia) in antiphospholipid antibody-positive patients. This paper reports a case of a 29-year-old male without the underlying disease who developed extensive mesenteric thromboembolism and jejunal necrosis during the treatment for acute enteritis. The patient's condition was improved with low-molecular-weight heparin and an intravenous Ig treatment with emergency surgery. The serum antiphospholipid (anticardiolipin IgM) and lupus anticoagulant antibody tests showed positive results. Acute infectious enterocolitis is generally considered a mild disease. On the other hand, aggressive evaluation and treatment should be considered if the clinical conditions do not improve and deteriorate rapidly despite appropriate antibiotic treatment because of the possibility of acute immunological complications, such as catastrophic antiphospholipid syndrome. (Korean J Gastroenterol 2021;77:294-299)

KCI등재

6상피하종양 형태로 발현된 호산구성 대장염 1예

저자 : 윤정희 ( Jeonghui Yun ) , 박상규 ( Sanggyu Park ) , 박호준 ( Hojun Park ) , 임원 ( Won Lim ) , 이태영 ( Taeyeong Lee ) , 송철수 ( Chulsoo Song )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 300-304 (5 pages)

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Eosinophilic colitis is a rare disease that is characterized by eosinophilic infiltration in the colon wall in symptomatic patients. Thus far, the epidemiology and pathophysiology of eosinophilic colitis have not been well defined, but the hypersensitivity response is likely to play a role in its pathogenesis. The clinical presentation of eosinophilic colitis is usually nonspecific and depends on the layer of the intestinal wall affected by the eosinophilic infiltrate. Eosinophilic colitis is diagnosed generally by exclusion, i.e., after all other causes of eosinophilic infiltration have been excluded. Although there is no consensus over its diagnostic criteria, the laboratory results and radiology and endoscopy findings can provide important diagnostic evidence. This paper reports a case of eosinophilic colitis presenting as subepithelial tumor-like lesions in a 41-year-old man with the chief complaints of abdominal pain and loose stools. The patient had no diseases and no food or drug allergies in his medical history. In general, the endoscopic findings of eosinophilic colitis can vary from a normal mucosa to frank ulcerations. In this case, however, endoscopy revealed subepithelial tumor-like lesions. The colon biopsy showed eosinophilic infiltration in the lamina propria. The patient was treated with steroids, and his symptoms regressed with no signs of relapse. (Korean J Gastroenterol 2021;77:300-304)

KCI등재

7대장 종괴로 오인한 Sevelamer 연관성 직장 궤양

저자 : 이진희 ( Jin Hee Lee ) , 박상형 ( Sang Hyoung Park ) , 신진호 ( Jin Ho Shin ) , 홍승모 ( Seung-mo Hong ) , 박진화 ( Jin Hwa Park ) , 황성욱 ( Sung Wook Hwang ) , 양동훈 ( Dong-hoon Yang ) , 변정식 ( Jeong-sik Byeon ) , 명승재 ( Seung-jae Myung ) , 예병덕 ( Byong Duk Ye ) , 양석균 ( Suk-ky

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 305-308 (4 pages)

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The phosphorous balance is clinically important in increasing the long-term outcomes and preventing complications of end-stage renal disease. Sevelamer is a phosphate binder used widely to regulate hyperphosphatemia. On the other hand, gastrointestinal side effects increase with increasing sevelamer intake. A 29-year-old male with end-stage renal disease of IgA nephropathy on maintenance hemodialysis was admitted for diffuse alveolar bleeding and pneumonia. He presented with a low-grade fever and watery diarrhea tinged with blood. Initially, a Clostridioides difficile-associated diarrhea treatment was started with positive findings of Clostridioides difficile toxin and culture. Despite this, there was no improvement in the symptoms even with the appropriate antibiotic treatment. Computed tomography of the abdomen and pelvis revealed an occlusive mass in the rectum and secondary obstructive changes in the sigmoid colon. The initial suspicion was a malignancy or fungal infection. Sigmoidoscopy with a biopsy identified the mass as a lump of mucous material with the entire lumen covered with exudate. The subsequent histopathology examination revealed a colonic mucosal injury and characteristic ''fish scale"-like sevelamer crystals in the exudate. The diagnosis of a sevelamer-induced rectal ulcer was made. We report this case of a sevelamer-associated rectal ulcer of the sigmoid. (Korean J Gastroenterol 2021;77:305-308)

KCI등재

8Russell Body Lesions of the Colon: Case Report and Literature Review

저자 : W. Keith Tan , Rachel Smith , Anthony George , Anita Gibbons , Syed Shaukat , Rizwan Kassam , Phil Roberts

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 309-312 (4 pages)

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Russell bodies (RB) are rare manifestations within the lower gastrointestinal tract. To date, there are only three other reported cases of RB lesions of the colon; two were polyps, and the third was a case of a multifocal RB lesion of the gastrointestinal tract. This paper reports a case of a tubulovillous adenoma with RB of the sigmoid colon in a patient diagnosed incidentally as part of the UK National Health Service Bowel Cancer Screening Programme. A thorough hematological investigation is required to exclude hematological malignancies because of its association with plasma cell neoplasm. These lesions should undergo clonality analysis to exclude the monoclonal proliferation of plasma cells. Ideally, a bone marrow aspirate and investigations for amyloidosis should be performed to exclude underlying hematological malignancies. (Korean J Gastroenterol 2021;77:309-312)

KCI등재

9급성 가성 장폐쇄로 발현된 신경이완제 악성 증후군 1예

저자 : 류성주 ( Sung Ju Ryu ) , 이종윤 ( Jong Yoon Lee ) , 이종훈 ( Jong Hoon Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 313-316 (4 pages)

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A colonic pseudo-obstruction is a disorder that causes abdominal distension and abdominal pain similar to a mechanical obstruction, but there are no structural lesions that can obstruct the gastrointestinal tract. This condition can be acute or chronic. An acute colonic pseudo-obstruction, also called Ogilvie's syndrome, is believed to be a condition induced by other causes that are different from a chronic colonic pseudo-obstruction. The pathogenesis involves abnormalities in the autonomic nervous system induced by systemic diseases or medications, and it often improves when the primary causes are treated. On the other hand, a chronic colonic pseudo-obstruction can occur repeatedly without a particular cause. The authors encountered neuroleptic malignant syndrome that caused acute colonic pseudo-obstruction. This paper reports a case with a review of the relevant literature. This is the first case reported in Korea. This case shows that physicians should consider neuroleptic malignant syndrome as a cause of an acute colonic pseudo- obstruction. (Korean J Gastroenterol 2021;77:313-316)

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10대장 과립세포 종양

저자 : 이창민 ( Chang Min Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 77권 6호 발행 연도 : 2021 페이지 : pp. 317-320 (4 pages)

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(2006)홍길동 외 1명심리학41회 피인용

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