간행물

대한피부과학회> 대한피부과학회지

대한피부과학회지 update

Korean Journal of Dermatology

  • : 대한피부과학회
  • : 의약학분야  >  피부과학
  • : KCI등재
  • : SCOPUS
  • : 연속간행물
  • : 월간
  • : 0494-4739
  • : 2713-7627
  • :

수록정보
수록범위 : 1권1호(1960)~60권7호(2022) |수록논문 수 : 9,717
대한피부과학회지
60권7호(2022년 08월) 수록논문
최근 권호 논문
| | | |

KCI등재 SCOPUS

저자 : 박효진 ( Hyo Jin Park ) , 장현준 ( Hyun Joon Chang ) , 김태근 ( Tae Geun Kim ) , 권미연 ( Mi Yeon Kwon ) , 임채윤 ( Chae Yoon Lim ) , 주현정 ( Hyun Jeong Ju ) , 이경호 ( Kyung Ho Lee ) , 박철종 ( Chul Jong Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 409-413 (5 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기

Background: Psoriasis is a T cell-mediated disorder. Appropriate treatment of psoriasis can result in a plethora of dynamic changes in the T cells and their cytokine production. Studies on the expression of Th1 and Th17 inflammatory cytokines after various treatments have reported inconsistent results.
Objective: This study aimed to investigate the changes in inflammatory cytokine expression in psoriasis skin lesions before and after psoriasis treatment.
Methods: Five patients with plaque psoriasis were enrolled in the study. The tissue mRNA and protein levels of interleukin (IL)-12, IL-2, interferon (IFN)-γ, IL-23, IL-17A, and IL-22 in psoriatic skin lesions before and after psoriasis treatment were detected using real-time polymerase chain reaction and immunohistochemical staining, respectively.
Results: The decrease in the psoriasis area and severity index was accompanied by a reduction in IL-12 and IL-23 mRNA levels and a concomitant reduction of IL-2 and IL-17A protein levels in psoriasis skin lesions. Both mRNA and protein levels of IFN-γ in psoriatic skin lesions increased after treatment.
Conclusion: The mRNA levels of tissue inflammatory cytokines (IL-12 and IL-23) and the protein levels of tissue inflammatory cytokines (IL-2 and IL-17A) significantly decreased after psoriasis treatment. The mRNA and protein levels of IFN-γ increased, even after psoriasis treatment. (Korean J Dermatol 2022;60(7):409∼413)

KCI등재 SCOPUS

저자 : 이주희 ( Joo Hee Lee ) , 최수연 ( Sooyeon Choi ) , 김제민 ( Jemin Kim ) , 이영인 ( Young In Lee ) , 이주희 ( Ju Hee Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 414-419 (6 pages)

다운로드

(기관인증 필요)

초록보기

Background: Postoperative scars following cleft lip surgery are frequently accompanied by cosmetic and functional problems; therefore, patients with cleft lip scars usually undergo various long-term scar treatment courses. Currently, only a limited number of fractional laser treatment cases of cleft lip scars have been reported.
Objective: This study aimed to evaluate the safety and efficacy of the combination laser treatment for hypertrophic scar management following cleft lip surgery.
Methods: This single-center retrospective study included 27 patients who underwent cleft lip surgery before 12 months of age. The control group comprising 13 patients received only a silicone gel or sheet for the scars, while the treatment group comprising 14 patients underwent laser treatment with a 1,550 nm non-ablative fractional erbium-glass laser, followed by a 10,600 nm ablative fractional carbon dioxide laser. Intralesional triamcinolone injection (5∼10 mg/mL) was administered immediately after laser treatment. Scar improvement was assessed at 1, 3, and 6 months after surgery using the Vancouver Scar Scale.
Results: The mean total Vancouver scar scale showed a statistically significant improvement in the treatment group compared to that in the control group. In the sub-analysis of pigmentation, the vascularity, pliability, and height significantly improved in the treatment group. No differences in the patients' baseline characteristics between the two groups were noted. No significant adverse effects were observed during the follow-up.
Conclusion: Combination laser therapy using fractional lasers and intralesional triamcinolone injection is safe and effective for managing cleft lip surgery scars in infantile patients. (Korean J Dermatol 2022;60(7):414∼419)

KCI등재 SCOPUS

저자 : 이수민 ( Su Min Lee ) , 고병창 ( Byeong Chang Ko ) , 안상우 ( Sang Woo Ahn ) , 어지안 ( Ji An Uh ) , 설정은 ( Jung Eun Seol ) , 김효진 ( Hyojin Kim ) , 이수경 ( Soo Kyung Lee ) , 김명신 ( Myoung Shin Kim ) , 이운하 ( Un Ha Lee ) , 박소희 ( So Hee Park ) , 정소영 ( So Young Jung ) , 박혜진 (

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 420-428 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background: Biologics-experienced patients are more likely to show a lower response to biologics than that of biologic-naïve patients. However, no consensus on switching biologics exists.
Objective: We aimed to investigate the switching patterns and efficacy of the switched biologics in patients with moderate-to-severe psoriasis in actual clinical practice.
Methods: This multicenter retrospective study included 37 patients with a history of switching biologics. We analyzed the reasons for switching, the switching patterns, and psoriasis area and severity index (PASI) 75 response rates after switching biologics. We also analyzed the factors affecting the PASI75 response rate to the second biologic.
Results: The reasons for switching baseline biologics were primary failure in five patients (13.5%), secondary failure in 28 patients (75.7%), and adverse events in four patients (10.8%). The second biologics prescribed mostly include interleukin (IL)-23 inhibitor in twenty-four patients (64.9%), IL-17 inhibitor in eight patients (21.6%), tumor necrosis factor-α inhibitor in three patients (8.1%), and IL-12/23 inhibitor in two patients (5.4%). A total of 46% of patients (17/37) switched biologics from IL-12/23 inhibitors to IL-23 inhibitors. The PASI75 response rates at the primary endpoint of the second and third biologics were 89.2% and 88.8%, respectively. Our study found that female sex and obesity were associated with the primary failure of the second biologic.
Conclusion: Secondary failure was the most common reason for switching baseline biologics. Korean dermatologists prefer different classes of biologics while switching. The PASI75 response rates at the primary endpoints of the second and third biologics were relatively satisfactory. (Korean J Dermatol 2022;60(7):420∼428)

KCI등재 SCOPUS

저자 : 이기욱 ( Gi-wook Lee ) , 배경남 ( Kyung-nam Bae ) , 손진화 ( Jin-hwa Son ) , 신기혁 ( Kihyuk Shin ) , 김훈수 ( Hoon-soo Kim ) , 고현창 ( Hyun-chang Ko ) , 김병수 ( Byungsoo Kim ) , 김문범 ( Moon-bum Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 429-435 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: Green nail syndrome (GNS) is characterized by a greenish discoloration of the nail with accompanying nail apparatus disorders, such as onycholysis or paronychia. To date, data on the clinical characteristics of GNS are limited, especially in Korea.
Objective: This study aimed to investigate the clinical characteristics of GNS.
Methods: We retrospectively reviewed the medical records and clinical photographs of 78 patients with 91 GNS lesions diagnosed at the Pusan National University Hospitals (Busan and Yangsan) from 2009 to 2021.
Results: Among 78 patients, 47 (60.3%) were female and 31 male (39.7%), with a mean age of 53.1 years (23∼82 years). This study included 56 fingernail (61.5%) and 35 toenail lesions (38.5%). Thumbnails and great toenails were the most common site, with 62 lesions (68.1%). Most patients presented predisposing conditions, such as frequent exposure to wet conditions (55.1%), immunosuppressive conditions (26.9%), and trauma history (29.5%). The most common colors, shapes, and eccentricities of GNS were blackish-green (31.9%), reverse triangle (53.8%), and distal eccentricity (42.9%), respectively. The GNS was accompanied by various nail diseases that mostly (80.2%) preceded the syndrome, and onycholysis was the most common (83.5%). Based on the involvement of the nail surface or subsurface, GNS can be divided into the superficial (15.4%), subungual (73.6%), and mixed (11.0%) subtypes, each of which shows different clinical features, such as multiplicity, color, shape, and eccentricity.
Conclusion: This is the largest-scale study showing the clinical characteristics of GNS and can be helpful for dermatologists who usually and primarily treat GNS. (Korean J Dermatol 2022;60(7):429∼435)

KCI등재 SCOPUS

저자 : 신준오 ( Jun-oh Shin ) , 배경남 ( Kyung-nam Bae ) , 김훈수 ( Hoon-soo Kim ) , 고현창 ( Hyun-chang Ko ) , 김병수 ( Byungsoo Kim ) , 김문범 ( Moon-bum Kim ) , 신기혁 ( Kihyuk Shin )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 436-439 (4 pages)

다운로드

(기관인증 필요)

초록보기

Setleis syndrome, also known as the focal facial dermal dysplasia type 3, is characterized by atrophic scar-like lesions in both the temporal regions and other facial abnormalities. The syndrome is associated with a mutation in the TWIST2 gene and is inherited as an autosomal recessive pattern. Here, we describe a case of an 18-year-old woman and her 10-year-old brother with bitemporal depressed patches. The lesions were observed at birth, but they were replaced by atrophic patches after several months. No abnormalities in growth or development were observed. Histopathologic findings showed atrophy of the epidermis and loss of appendages, such as hair follicles and adnexal glands, in the atrophic patches compared to that of the adjacent normal skin. (Korean J Dermatol 2022;60(7):436∼ 439)

KCI등재 SCOPUS

저자 : Sang-min Choi , Bark-lynn Lew , Woo-young Sim , Soon-hyo Kwon

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 440-443 (4 pages)

다운로드

(기관인증 필요)

초록보기

Dermatofibroma (DF) is one of the most common benign soft tissue tumors. Various histological variants of DF have been described, and it is important to discern the different variants to evaluate the prognosis. A 43-year-old female patient with no specific medical history presented with multiple brown-colored nodules on the right arm for 5 years. Biopsy specimens showed a predominance of collagen and fibroblasts in a whorled arrangement with moderate cellularity, findings that were consistent with fibrocollagenous DF. The patient underwent excision of the largest lesion and revisited our department 3 months after surgery with local recurrence at the excision site. We report a rare case of multiple fibrocollagenous DF with local recurrence at the excision site. (Korean J Dermatol 2022;60(7):440∼443)

KCI등재 SCOPUS

저자 : Hae Eun Park , Ju Hee Han , Yeong Ho Kim , Ji Hyun Lee , Young Min Park , Hwa Young Lee , Chul Hwan Bang

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 444-448 (5 pages)

다운로드

(기관인증 필요)

초록보기

Leukocytoclastic vasculitis after the BNT162b2 vaccine and ChAdOx1 nCoV-19 Corona Virus vaccine [recombinant] has been observed. Herein, we report two cases of leukocytoclastic vasculitis that developed after the ChAdOx1-S [recombinant] vaccination. A 61-year-old and a 52-year-old woman presented with pruritic purpuric macules and papules on both lower legs. The patients had been vaccinated with the ChAdOx1-S [recombinant] vaccine. The histopathological analyses were consistent with a diagnosis of leukocytoclastic vasculitis. They were treated with oral prednisolone and improved within 1 month of treatment. We assume that the rash had arisen from the deposition of spike protein at the skin tissue induced by the viral vector of the COVID-19 vaccine or hyperimmune responses by excipients present in vaccine preparations. To our knowledge, our cases would be the first Korean cases of leukocytoclastic vasculitis after the ChAdOx1-S [recombinant] vaccination. (Korean J Dermatol 2022;60(7):444∼ 448)

KCI등재 SCOPUS

저자 : 어지안 , 김중호 , 이재호 , 이수경 , 김명신 , 이운하

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 449-450 (2 pages)

다운로드

(기관인증 필요)

초록보기

KCI등재 SCOPUS

저자 : 윤지상 , 배경남 , 손진화 , 김훈수 , 고현창 , 김병수 , 김문범 , 신기혁

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 451-452 (2 pages)

다운로드

(기관인증 필요)

초록보기

KCI등재 SCOPUS

저자 : 권혁진 , 유동화 , 박경덕 , 김기호 , 윤정호

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 60권 7호 발행 연도 : 2022 페이지 : pp. 453-454 (2 pages)

다운로드

(기관인증 필요)

초록보기
12
권호별 보기

내가 찾은 최근 검색어

최근 열람 자료

맞춤 논문

보관함

내 보관함
공유한 보관함

1:1문의

닫기