간행물

대한뇌종양학회지

Journal of Korean brain tumor society

  • : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회
  • : 의약학분야  >  신경외과학
  • :
  • :
  • : 연속간행물
  • : 반년간
  • : 1598-530x
  • :
  • : 대한뇌종양학회지(~2012) → brain tumor research and treatment(2013~)

수록정보
5권1호(2006) |수록논문 수 : 10
간행물 제목
11권2호(2012년 09월) 수록논문
최근 권호 논문
| | | |

1임상 : 내시경을 사용한 경비적 경접형동 수술에서의 뇌척수액 유출 예방에 대한 고찰

저자 : 박준상 ( Jun Sang Park ) , 강석구 ( Seok Gu Kang ) , 홍용길 ( Yong Gil Hong ) , 전신수 ( Sin Soo Jeun )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 77-82 (6 pages)

다운로드

(기관인증 필요)

초록보기

Objectives:The endoscopic endonasal transsphenoidal approach (EETSA) is increasingly being used to treat pituitary adenomas and other sellar/suprasellar pathologies. One important complication of the transsphenoidal approach is cerebrospinal fluid (CSF) leakage, which occurs in 0.4 to 9% of cases. We report our experience with EETSA and describe the me-thods that we use to prevent CSF leakage. Methods:A single surgeon performed EETSA on 170 consecutive patients between Feb 2004 and Apr 2011. Patients were divided into three groups based on their CSF leakage status as follows: no CSF leakage, minor CSF leakage, and major CSF leakage. Sellar floor reconstruction was performed according to this classification. In the no-CSF leakage group, sellar floor reconstruction was performed with oxidative cellulose (Surgicel®) only. In the second group (minor CSF leakage), sellar floor reconstruction was performed using autologous fat and bone grafts. Patients in the third group (major CSF leakage) underwent an additional reconstructive procedure of the skull base using the pedicled septal mucosal flap. Results:Of 170 patients, 30 (17.6%) showed CSF leakage in the operation field ; 24 (14.1%) were classified as having minor CSF leakage and 6 (3.5%) patients were classified as having major CSF leakage. Post-operative CSF leakage occurred in only two cases. Conclusion:CSF leakage, though relatively common in the operation field, can be prevented effectively with adequate reconstruction techniques. Assignment of patients to one of three groups based on their CSF leakage in the operation field and sellar floor reconstruction based on this classification resulted in favorable postoperative outcomes.

2임상 : 원발성 신경교육종에 대한 단일기관의 임상성적

저자 : 변준호 ( Joon Ho Byun ) , 윤정호 ( Jung Ho Yun ) , 조영현 ( Young Hyun Cho ) , 김정훈 ( Jeong Hoon Kim ) , 김창진 ( Chang Jin Kim )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 83-87 (5 pages)

다운로드

(기관인증 필요)

초록보기

Objectives:Primary gliosarcoma (GSM) is a rare central nervous system tumor with few reports described in the literature. Here, we present our clinical experience and the outcome of primary GSM patients in a single medical center. Method:Primary GSM patients who were treated at our institution between 1990 and 2011 were selected retrospectively. All patients were analyzed by meticulous chart review including clinical and pathologic data. Overall survival was analyzed by Kaplan-Meier survival analysis. Results:Eleven patients were diagnosed with primary GSM. It was 1.7% of glioblastoma (GBM) during the same period. The overall median survival of the 11 patients was 12 months (range : 3 to 177 months). Patients who underwent maximal safe resection had a prolonged median survival compared to those who only underwent biopsy of the tumor (12 vs. 6 months, p=0.288). All patients received adjuvant postoperative radiotherapy and 7 of 11 patients received chemotherapy with temozolomide. Four patients received gamma-knife radiosurgery for local recurrence; however, treatment method by gamma-knife radiosurgery was not significantly associated with prolonged survival in this study. Patients who received re-explorative surgery for resectable recurred tumors had a prolonged median survival compared to those who had non-resectable recurred tumors (14 vs. 6 months, p=0.0082). Conclusion:We present 11 primary GSM patients who were treated according to the standard treatment for GBM. Despite aggressive multimodality treatment, the life expectancy of GSM is very short until now. Therefore, large and comprehensive clinical investigations are needed to establish the standard treatment for primary GSM.

3임상 : 악성 뇌교종의 유전자 검사 : 방사선학적 특징과 예후와의 관계

저자 : 유재원 ( Jae Won Yu ) , 김영준 ( Young Zoon Kim ) , 송영진 ( Young Jin Song ) , 김대철 ( Dae Cheol Kim ) , 한진영 ( Jin Yeong Han ) , 김기욱 ( Ki Uk Kim )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 88-95 (8 pages)

다운로드

(기관인증 필요)

초록보기

Objectives:Numerous genetic alterations are related to tumorigenesis and influence the radiological features of malignant glial tumor. We performed a cytogenetic analysis from a fresh tumor specimen and analyzed its relationship with radiological features and prognosis. Materials and Methods:Among the 29 patients with malignant glial tumor involved in cytogenetic analysis, 19 cases showing chromosomal abnormality were analyzed. Cytogenetic analysis was performed with pathologically proven fresh surgical specimen. Both medical records and radiological findings were reviewed to define the tumor, to evaluate peritumoral edema and to assess treatment results. Results:The most frequent genetic abnormality was observed in chromosome 7 (57.8 %). Complex karyotype presenting three or more abnormalities was noted in 11 cases (57.8 %). Chromosomal abnormalities, noted in more than three cases, were whole loss of Y (7 cases), whole gain of 7 (6 cases), whole gain of 2, whole gain of 5, whole gain of 12, 19q gain, 6p loss, 9p loss, and whole gain of 13 (3 cases). We reported that loss of chromosome 7 related to MDR-1 (Multidrug resistant gene) were correlated with good response of chemotherapy. Conclusions:A chromosomal analysis of malignant glioma can be perfomed to discover tumorigenic factors and to evaluate radiological features. Results of karyotyping is closely related to the clinical outcome and may be utilized in developing new therapeutic modalities.

4임상 : 경접형동 접근에 의한 뇌하수체 선종 제거술 후 발생한 지연성 저나트륨혈증 : 임상 연구

저자 : 김정재 ( Jung Jae Kim ) , 김선호 ( Sun Ho Kim ) , 김의현 ( Eui Hyun Kim )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 96-101 (6 pages)

다운로드

(기관인증 필요)

초록보기

Objective:Delayed hyponatremia is a common complication after transsphenoidal surgery (TSS) for pituitary adenomas. We retrospectively evaluated our patients and tried to find possible associated risk factors of delayed hyponatremia. Methods:From 2006 until 2010, total 575 cases of pituitary adenomas were operated with TSS in a single institution. Thirty-one patients (5.3%) with delayed hyponatremia were compared to other 544 patients without delayed hyponatremia in the aspects of age, sex, Hardy classification, tumor size, hormonal type and activity on preoperative combined pituitary function test. Their postoperative outcomes were also evaluated in the aspects of tumor removal fashion and hormonal outcome on postoperative combined pituitary function test. Results:In 31 patients, delayed hyponatremia started 7.0 days after surgery (range : postoperative day 3-10). At the time of diagnosis of hyponatremia, serum level of sodium ranged from 111 mmol/L to 132 mmol/L (mean : 120.5 mmol/L) and mean duration of treatment was 4.l days (range : 2-9 days). Piecemeal tumor removal was more frequent in a group with delayed hyponatremia (p=0.035). The presence of postoperative hypopituitarism and aggravation of pituitary function were observed more frequently in a group with delayed hyponatremia (p=0.002 and p=0.017, respectively). Conclusion:Delayed hyponatremia is a common complication after TSS and potentially fatal. Piecemeal fashioned tumor removal, postoperative hypopituitarism and aggravation of pituitary function are associated with higher chance of delayed hyponatremia.

5임상 : 뇌실질 전이가 있는 비소세포성 폐암 환자에서의 연수막 전이 빈도 및 예후 인자

저자 : 나영철 ( Young Cheol Na ) , 김지희 ( Ji Hee Kim ) , 김창환 ( Chang Hwan Kim ) , 장원석 ( Won Seok Chang ) , 장진우 ( Jin Woo Chang ) , 박용구 ( Yong Gou Park )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 102-107 (6 pages)

다운로드

(기관인증 필요)

초록보기

Objectives:The object of this study is to evaluate the incidence, survival and the prognostic factors in patients with leptomeningeal metastasis from non-small cell lung cancer. Methods:The study included fifty-five consecutive patients diagnosed with brain parenchymal metastasis on magnetic resonance image (MRI) clinically from non-small cell lung cancer between July 2010 and February 2011. All the patients underwent lumbar puncture for cerebrospinal fluid examination including cytology examination with cytokeratine immunostain. If the patients showed positive in cerebrospinal cytology or leptomeningeal enhancement on T1 weighted gadolinium enhanced MRI, whole spine MRI with gadolinium enhancement was also taken for evaluation of spinal disease. For evaluation of prognostic factors, we investigated the patient's age, interval from the time of diagnosis of systemic disease to the time of diagnosis of leptomeningeal metastasis, interval from the time of diagnosis of parenchymal metastasis to the time of diagnosis of leptomeningeal metastasis, performance status of the patients, and following treatment modality after diagnosis of leptomeningeal metastasis. Result:In eleven (20%) of the fifty-five patients, the diagnosis of leptomeningeal metastasis was made on the basis of MRI findings and the results from cerebrospinal fluid cytology. Among those eleven patients, eight (72.7%) had positive cerebrospinal fluid cytology at the time of initial examination. Eight of the eleven patients underwent an operation for intraventricular catheter and reservoir placement in order to receive intraventricular chemotherapy. In six (75%) of the eight intraventricular chemotherapy patients, the negative conversion of cerebrospinal fluid cytology was achieved during induction chemotherapy of four weeks. The overall median survival for the eleven patients after the diagnosis of leptomeningeal metastasis and the eight subsequent intraventricular chemotherapy patients was 62 days (95% confidence interval 27.4 96.6). The most possible prognostic factor was the intervals from primary disease to leptomeningeal metastasis (p=0.071). Conclusion:In this study, we found that relatively high proportion of the patients of non-small cell lung cancer with parenchymal metastases were co-morbided by leptomeningeal metastases, and revealed that the interval from primary disease to leptomeningeal metastasis could be an important factor for survival. However, further well-designed investigations, with larger sample sizes, must be conducted to evaluate other prognostic factors as well as new drugs, and to define the optimal treatment combinations and route.

6임상 : 측뇌실 삼각에 발생한 뇌실내 수막종에 있어 상부 두정-후두 피질경유 접근법의 임상 결과 ; 24례 보고

저자 : 박세환 ( Se Hwan Park ) , 조진모 ( Jin Mo Cho ) , 김의현 ( Eui Hyun Kim ) , 김선호 ( Sun Ho Kim ) , 이규성 ( Kyu Sung Lee ) , 장종희 ( Jong Hee Chang )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 108-113 (6 pages)

다운로드

(기관인증 필요)

초록보기

Introduction:Intraventricular meningiomas are uncommon subtype of intracranial meningiomas. Trigonal meningiomas consist of the majority of intraventricular meningiomas. The superior parieto-occipital transcortical approach is the most popular approach for removal of them. We analyzed our experience in removal of the trigonal meningiomas that were resected using the superior parieto-occipital transcortical approach. Patients and Methods:Twenty-four patients underwent surgical removal of trigonal meningioma from 1997 to May 2012. Demographics, clinical features, surgical outcomes, histopathologic results and prognosis were analyzed. Results:Study population had a mean age of 51.2 years and a female preponderance of 1 : 1.7. The most common presenting symptom was chronic headache, which was followed by memory impairment, visual disturbance and hemiparesis. Total removal of the tumor was achieved in all cases. Twenty-two (91.7%) tumors were World Health Organization (WHO) grade I while two cases were WHO grade III. There were two cases of intracerebral hemorrhage in the surgical corridor, one case of transient contralateral hemiparesis with cognitive decline, one case of transient contralateral homonymous hemianopsia, one case of aggravation of visual field defect, and one case of hydrocephalus which was successfully treated by ventriculo-peritoneal shunt. Conclusion:The superior parieto-occipital approach is suitable for most of the trigonal meningiomas and total removal of them can be achieved safely.

7임상 : Leksell Gamma Knife Perfexion과 Model C의 치료계획 효용성 비교 : 임상연구

저자 : 김정재 ( Jung Jae Kim ) , 김기홍 ( Gi Hong Kim ) , 박용구 ( Yong Gou Park ) , 장종희 ( Jong Hee Chang )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 114-117 (4 pages)

다운로드

(기관인증 필요)

초록보기

Objective:The purpose of this study was to compare the dose planning between the Leksell Gamma Knife Perfexion (LGK PFX) and the Leksell Gamma Knife C (LGK C) using variable indices. Methods:A total of 100 cases, which were composed of 35 meningiomas, 20 vestibular schwannomas, 35 metastases, and 10 pituitary adenomas, were enrolled in this study. First, these cases were treated with the LGK PFX and then, were re-planned with the LGK C. We compared these two models in terms of the number of shots, the percentage of coverage, the conformity index (CI), Paddick's conformity index (PCI), the gradient index (GI), and the beam on time. Results:The LGK PFX completely outperformed the LGK C in terms of GI and the LGK PFX tended to have a longer beam on time than that of the LGK C. However, in patients with schwannomas, the LGK PFX outperformed the LGK C in terms of the CI, PCI, and GI, and in patients with pituitary adenomas, the LGK PFX outperformed the LGK C in terms of the percentage of coverage, PCI, and GI with statistical significance. Conclusion:The LGK PFX is an entirely redesigned radiosurgery unit accompanied by the development of software. The LGK PFX is supposed to achieve highly conformal dose prescription consisting of many isocenters with a reasonable treatment time.

8증례 : 신경섬유종증 제1형, 2형과 구분되는 신경집종증에 대한 1례

저자 : 양순범 ( Soon Bum Yang ) , 장웅규 ( Ung Kyu Chang ) , 윤상민 ( Sang Min Youn )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 118-121 (4 pages)

다운로드

(기관인증 필요)

초록보기

Multiple schwannomas without vestibular schwannomas (schwannomatosis) are new classification of neurofibromatoses. Understanding of this disease entity is emerging, recently. We experienced a case of schwannomatosis, and reviewed some literatures related to schwannomas. A 45-year-old woman visited our hospital with low back pain and radiating leg pain. The patient's spine MR images revealed that she had multiple intradural extramedullary masses in lumbar spinal canal, extending to paravertebral space through neural foramen. On brain MR images, there were no vestibular schwannomas. We took a operation to resolve her symptoms. After we removed the intradural extramedullary masses in lumbar spinal canal, her symptoms were improved.

9증례 ; 적갈색방사선학적 악성이나 조직학적으로 양성을 보인 신경절교종 - 증례보고 -

저자 : 김환수 ( Hwan Soo Kim ) , 정세헌 ( Se Heun Joung ) , 허원 ( Weon Heo ) , 이동열 ( Dong Youl Rhee )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 122-126 (5 pages)

다운로드

(기관인증 필요)

초록보기

Gangliogliomas are rare tumors of the central nervous system, composed of neoplastic ganglion cells and neoplastic glial cells. They are characterized by slow growing, low incidence of malignancy, surgically curable, and usually occurred in children and young adults. We report a case of ganglioglioma occurred in 21 year-old male which radiological findings were compatible with the malignancy but histologically diagnosed as benign, with review of literatures.

10증례 : 송과체에 발생한 교모세포종

저자 : 강무성 ( Moo Sung Kang ) , 홍창기 ( Chang Ki Hong ) , 김세훈 ( Se Hoon Kim ) , 이규성 ( Kyu Sung Lee )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 11권 2호 발행 연도 : 2012 페이지 : pp. 127-132 (6 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기

Pineal gland tumors comprise 0.4-1% of adult intracranial tumors. Glioblastoma, which is the most frequent glioma in brain tumors, is extremely rare in the pineal region. A 74-year-old man complaining of gait disturbance, urinary incontinence, and memory disturbance underwent ventroperitoneal (VP) shunt under the impression of obstrctive hydrocephalus that occurred secondarily to a tumor in the pineal gland. He refused treatment for the tumor. The symptoms were improved after the VP shunt. Six months postoperatively, he experienced a reaggravation of symptoms. An increase in tumor size was disclosed in brain imaging studies. The patient underwent an occipital craniotomy with occipital trans-tentorial approach. Pathological findings were consistent with glioblastoma. This case emphasizes the importance of considering glioblastoma as a differential diagnosis of pineal gland tumors, particularly if peritumoral heterogenous enhancement is observed. The role of surgery, chemotherapy, and radiotherapy on survival duration is not yet well established. Therefore, studies exploring the effect of each modalities on survival duration are needed.

12
권호별 보기
같은 권호 수록 논문
| | | | 다운로드

1종설 : 송과체 부위 종양; 수술적 해부 및 접근방법

저자 : 김일섭 ( Il Sup Kim ) , 이상원 ( Sang Won Lee )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 3-11 (9 pages)

다운로드

(기관인증 필요)

초록보기

The pineal region tumor is one of the difficult ones to exposure and remove. Selecting an operative approach to the pineal region tumor involving the third ventricle requires an understanding of the microsurgical anatomy of the posterior third ventricle. There are variable surgical approaches to the pineal region. The approaches suitable for reaching the pineal region are the infratentorial supracerebellar, occipital transtentorial, posterior transcallosal, posterior transcortical and combined supra/infratentorial-transsinus approach. Considerations important in selecting one of these surgical approaches are reviewed from the anatomical viewpoint.

2종설 : 전두하 반구간 접근법

저자 : 박동혁 ( Dong Hyuk Park ) , 정용구 ( Yong Gu Chung )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 12-22 (11 pages)

다운로드

(기관인증 필요)

초록보기

The subfrontal interhemispheric approach offers safe access to lesions at anterior cranial fossa, including tumors like suprasellar craniopharyngiomas and meningiomas, and vascular diseases like anterior communicating artery or distal anterior cerebral artery aneurysms. Anatomic preservation of the pituitary stalk, hypothalamic structure, perforating vessels, anterior communicating complex, the visual pathway, and the olfactory nerves is often possible. This article describes traditional and modified versions of subfrontal interhemispheric approach from skin incision through dissection to closure. And the authors also describes merits, handicaps and possible complications of this approach.

3임상 : 성상세포종의 악성도와 TGF-β1 및 Smad4 발현의 상관관계

저자 : 김병주 ( Byung Joo Kim ) , 송근성 ( Geun Sung Song ) , 서영준 ( Young Jun Seo )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 23-28 (6 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기

Smads are signal transducers for the members of TGF-beta superfamily. Understanding the function of Smads in tumor cells is of paramount importance, since most tumors with defects in TGF-beta signaling still have functional components of Smads pathways that may play critical roles in determining the malignant phenotypes. Of these Smads, Smad4 is essential for TGF-beta signaling. The purpose of this study was to elucidate TGF-beta 1 and Smad4 protein expression in human astrocytomas and its pathological significance by using immunohistochemical technique. A total 54 astrocytomas among the patients who underwent operation at Pusan National University Hospital between Jan., 1996 and Dec., 2001 were included in the study. Histologically the tumors were graded as three groups according to the WHO grading system and 15 cases were in grade II(low grade astrocytoma), 19 cases in grade III(anaplastic astrocytoma) and 20 cases in grade IV(glioblastoma multiforme). As a result, TGF-¥a1 expression tended to increase with increasing grade of malignancy. Expression of Smad4 was higher in grade II astrocytoma than grade IV astrocytoma. The univariate analysis showed that there was significant difference between the malignancy and expression of TGF-¥a1 and Smad4(p<0.05). In conclusion, it is presented that reduced Smad4 expression and high TGF-¥a1 expression might be significantly associated with increased malignancy and invasiveness of astrocytoma.

4임상 : 쥐 골수 기질 세포의 면역 효과 세포로의 활성화

저자 : 김효창 ( Hyo Chang Kim ) , 강석구 ( Seok Gu Kang ) , 전신수 ( Sin Soo Jeun ) , 유도성 ( Do Sung Yoo ) , 허필우 ( Pil Woo Huh ) , 조경석 ( Kyung Souk Cho ) , 김달수 ( Dal Soo Kim ) , 박춘근 ( Chun Kun Park )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 29-38 (10 pages)

다운로드

(기관인증 필요)

초록보기

Object:Marrow stromal cells(MSCs) have been shown to have the capacity of orthodox and unorthodox plasticity. In this study, the authors tried to differentiate MSCs into immune effector cell and also to access in vitro cytotoxicity of MSCs from rat. Methods:Rat MSCs(rMSCs) were isolated by standard methodology and were activated by interleukin-2(IL-2), interleukin- 15(IL-15), colony stimulating factor GM-CSF, and combinations. Phenotypes of these various activated cells were determined using flow cytometry. The secreted protein from effector cells was estimated by enzyme-linked immunosorbent assay. Cytotoxicity of rMSCs and activated rMSCs against the target cells(9L rat glioma cell line) were estimated using visual survival cell assay. The expression of immune response related genes in activated cells was measured. Results:After various cytokines activation of rMSCs, the population of immune effector cells(CD8, CD161a) and immune reaction related proteins(IL-4, γ-INF) were increased. There was a significant cytotoxicity of rMSCs activated with various cytokine combinations. Apoptosis may be one of the lysis mechanism of target cells by activated rMSCs. The contributing genes could be γ-INF, FasL and perforin. Conclusion:This study suggests that rMSC may differentiate into immune effector cells and have cytotoxic capability against malignant glioma cells. However, we have to investigate orthotopic animal study for the proper translation.

5임상 : 한국인에서의 다형성 황색 성상세포종

저자 : 김정수 ( Jung Soo Kim ) , 정진명 ( Jin Myung Jung ) , 황수현 ( Soo Hyun Hwang ) , 이철희 ( Chul Hee Lee ) , 강동호 ( Chul Hee Lee ) , 한종우 ( Jong Woo Han )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 39-44 (6 pages)

다운로드

(기관인증 필요)

초록보기

Pleomorphic xanthoastrocytoma(PXA) belongs to a subcategory of World Health Organization(WHO) classification of tumors of the central nervous system.9) PXA locates typically superficually and affects young patients, who present most commonly with seizures. It was first described by Kepes in 19799,10) and in Korea by Park et al in 1982.23) The tumor has aggressive histological features, but relatively favorable prognosis. The published cases of these PXAs in Korea were reviewed including the author`s own two cases, which were treated by gross total resection. The major clinical, radiological and histopathological features of PXAs in Korean are discussed.

6증례 : 전두부 두개골을 침범한 염증성 근섬유모세포종 -증례보고-

저자 : 김태호 ( Tae Ho Kim ) , 최우진 ( Woo Jin Choe ) , 이승준 ( Seung Jun Lee ) , 이종주 ( Jong Joo Rhee ) , 이혜경 ( Hye Kyung Lee ) , 이채혁 ( Chae Heuck Lee ) , 김명수 ( Myoung Soo Kim )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 45-49 (5 pages)

다운로드

(기관인증 필요)

초록보기

Inflammatory myofibroblastic tumor(IMT) includes a diverse group of lesions characterized by inflammatory cell infiltration and variable fibrotic responses, which mimic neoplastic lesions. IMTs of the head and neck occur most commonly in the orbits, and their occurrence in the skull is rare. To our knowledge, only eight cases of IMTs of the skull(excluding cases in the eye and maxillary sinus) have been reported in Korea. We report a case of IMT involving the frontal bone. A 43-year-old man presented with right frontal pain. A right frontal scalp mass had been removed at another hospital one month ago, but the pain persisted. Brain computed tomography showed a suspected sclerotic lesion near the right coronal suture, with an enhancing epidural mass. A lesion of the frontal bone was removed by craniectomy. The cortical bone appeared pinkish-brown color. Dura mater adherent to the bone showed an inflammatory reaction and thickening and it was removed. Duroplasty and cranioplasty were performed. The pathology test indicated IMT. IMT must be distinguished from other infectious, granulomatous, and neoplastic lesions. It requires an aggressive approach including surgical intervention, with resection of all the bone and dura mater involved. We describe the diagnosis and treatment of skull IMT.

7증례 : 뇌실내 종양 수술 후 발생한 소뇌출혈

저자 : 구선호 ( Sun Ho Koo ) , 이덕구 ( Deok Gu Lee ) , 조성진 ( Seong Jin Cho ) , 변박장 ( Park Jang Byun )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 50-53 (4 pages)

다운로드

(기관인증 필요)

초록보기

One of the major complications of craniotomy is hemorrhage. Postoperative hemorrhages usually occur at the site of the operation but can also occur remotely. Although there are few reports in the literature, remote intracerebral hemorrhages cause significant morbidity and mortality. Our report a case of catastrophic cerebellar hemorrhage after intraventricular tumor surgery. Relevant literature are reviewed and discussed.

8증례 : 종양내 출혈을 동반한 뇌수막종 -증례보고-

저자 : 서영준 ( Young Jun Seo ) , 조원호 ( Won Ho Cho ) , 최병관 ( Byung Kwan Choi ) , 이상원 ( Sang Weon Lee ) , 송근성 ( Geun Sung Song ) , 최창화 ( Chang Hwa Choi )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 54-58 (5 pages)

다운로드

(기관인증 필요)

초록보기

Hemorrhage from meningioma is rarely reported. We report one patient with intratumoral hemorrhage with meningioma. A 43-year-old women presented with severe headache and right hemiparesis. Brain computed tomography and magnetic resonance images revealed a mass lesion with intratumoral hemorrhage in the left frontal lobe. Total removal of the tumor and hematoma could be achieved. The patient recovered uneventfully after the operation. Histologic findings are considered to be a atypical meningioma. The Ki-67 labelling index was high, which is considered proliferative property of meningioma. We review the relevant literature and discuss the possible mechanism of intratumoral hemorrhage in the meningioma.

9증례 : 전두골에 발생한 방사선 속발 골육종 -증례보고-

저자 : 강형래 ( Hyoung Lae Kang ) , 신준재 ( Jun Jae Shin ) , 박상근 ( Sang Keun Park ) , 황용순 ( Yong Soon Hwang )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 59-62 (4 pages)

다운로드

(기관인증 필요)

초록보기

This is a case of a 21-year-old woman who was treated primitive neuroectodermal tumor(PNET) when she was 12-yearold. At that time, we performed radical surgery, radiation therapy, and chemotherapy. Forehead mass has developed after 11 years. On computed tomography, high density mass was detected on frontal bone and this lesion was removed by surgical operation. After surgery, chemotherapy was done at two times. The histological diagnosis was postradiation osteosarcoma. Postradiation osteosarcoma is a rare complication of radiation therapy. It has histologically been high-grade and poor prognosis. However, complete remission was obtained in our case after a couple of surgical operation, chemotherapy. This is the first case of postradiation osteosarcoma to be reported in the domestic. We treated a patient who developed osteosarcoma in the frontal bone 11 years after radiotherapy for PNET in the cerebellum and achieved favorable outcome.

10증례 : 종양내 출혈의 급격한 감소 -증례보고-

저자 : 이승환 ( Seung Hwan Lee ) , 김태성 ( Tae Sung Kim ) , 박봉진 ( Bong Jin Park ) , 이봉암 ( Bong Arm Rhee ) , 임영진 ( Young Jin Lim )

발행기관 : 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 간행물 : 대한뇌종양학회지 5권 1호 발행 연도 : 2006 페이지 : pp. 63-66 (4 pages)

다운로드

(기관인증 필요)

초록보기

Spontaneous regression of intracranial tumor is rare and especially in case of intratumoral bleeding, it is hardly found in documented report. We experienced 34 year-old male patient with metastatic brain tumor from maxillary malignant melanoma which is turned into tumor bleeding, underwent rapid resolution of tumor bleeding. We report the clinical manifestation, radiological characteristics and histological aspect of this rare case with literature review.

1

내가 찾은 최근 검색어

최근 열람 자료

맞춤 논문

보관함

내 보관함
공유한 보관함

1:1문의

닫기