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Oral Biology Research (OBR) update

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수록정보
45권3호(2021) |수록논문 수 : 9
간행물 제목
46권2호(2022년 06월) 수록논문
최근 권호 논문
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KCI등재

저자 : Sool-heon Lee , Seong-jun Ham , Jeong-in Choi , Young-joon Kim , Jong-wook Moon

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 46권 2호 발행 연도 : 2022 페이지 : pp. 51-60 (10 pages)

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Tooth autotransplantation refers to tooth transplantation from the donor to the recipient site of the same individual. Occasionally, there are situations where autotransplantation cannot be carried out immediately at clinic. In such cases, donor teeth cryopreservation is necessary to overcome limited indications. Cryopreservation media and nutrients play essential roles in preserving the periodontal ligament cells' activity. Several studies have focused on cryopreservation media and nutrients. Platelet-rich plasma (PRP) contains lots of growth factors without inducing immunologic responses or pathologic complications. Therefore, self serum and PRP might be positive factors in the cryopreservation process for preserving the periodontal ligaments (PDLs) viability. In this study, beagle dog's incisors were cryopreserved for three months in different cryopreservation media, including Dulbecco's modified eagle medium (DMEM, containing DMSO), DMEM+20% self serum, DMEM+20% self serum+PRP, and DMEM+20% fetal bovine serum (FBS). Histological results revealed that DMEM+20% self serum+PRP and DMEM+20% FBS groups showed significantly less root resorption and higher regeneration of periodontal ligament cells and that PRP is a positive factor in the cryopreservation process to preserve PDLs viability. Therefore, cryopreservation media with PRP will be a good periodontal tissue regeneration option after long-term cryopreservation in a tooth autotransplantation procedure.

KCI등재

저자 : Jung-hyuk Lee , Seong-jun Ham , Jin-wook Shin , Cheol-woong Jeong , Jeong-in Choi , Young-joon Kim

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 46권 2호 발행 연도 : 2022 페이지 : pp. 61-70 (10 pages)

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The current study introduces photocurable macromolecular resin (KIS resin) and aims to assess its use as a basic material for implant surgical stent fabrication using 3D printing and the digital light processing (DLP) technique. The biological and physical properties of KIS resin were evaluated, and radiological analysis was performed to assess the clinical accuracy of a 3D-printed surgical stent. The physical characteristics were analyzed in accordance with the guidelines of certified standards, and cell adhesion analysis was performed to evaluate the viability of human gingival fibroblast (hGF) cells exposed to KIS resin and conventional orthodontic acrylic resin. Radiological analysis of animals was carried out by pairwise overlap of pre- and postoperative images. The physical characteristics of KIS resin met the ISO 20795-1, ASTM D695, and ASTM D638 standards. The hGF cells on KIS resin samples exhibited better cell attachment and connection compared to those exposed to conventional resins. The findings of the radiological analyses showed statistically significant differences in the deviations between DLP-printed surgical stents and conventional stents, with the horizontal linear deviations being smaller in the coronal and middle levels of the former. Moreover, the angular deviation was also smaller in the DLP stent group. Therefore, KIS resin exhibited favorable physical properties and cell viability, highlighting its potential for use as a basic material for 3D-printed implant surgical guides. Further evaluation of the use of implant surgical stents fabricated using KIS resin and the DLP method as a proper tool for implant placement with clinical utility should be carried out.

KCI등재

저자 : Jae-chan Jung , Sung-hoon Lim , Seo-rin Jeong

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 46권 2호 발행 연도 : 2022 페이지 : pp. 71-77 (7 pages)

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This study evaluated the effect of repetitive prestretching on hysteresis and abrupt force drops during the initial unloading phase (1-mm-unloading/peak force ratio) of elastomeric chains. Thirty samples of closed-type elastomeric chains were tested for each group of generation II power chain, energy chain, and memory chain. Elastomeric chains were elongated to a 100% extension from their original length of 12.5 mm and unloaded. Forces during the five loading and unloading cycles were determined. The memory chain showed significantly lower hysteresis than the generation II power chain and energy chain. Both loading and unloading forces were decreased significantly with repetitive prestretching. However, unloading forces decreased less than the loading force, thereby reducing the hysteresis. All three products showed the greatest hysteresis in the first cycle, which decreased significantly following repeated prestretching. The 1-mm-unload/peak ratio increased significantly until the 4th cycle, the cycle after triple prestretching. Conclusively, repetitive prestretching of elastomeric chains further decreased hysteresis and abrupt force drop during the initial 1-mm unloading, up to triple prestretching.

KCI등재

저자 : Jae-seok Kang , Byoung-eom Jung , Da-hyun Ko , Mee-kyoung Son

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 46권 2호 발행 연도 : 2022 페이지 : pp. 78-86 (9 pages)

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The purpose of this study was to investigate the impact of an implant with a blood pocket designed platform on the crestal bone by analyzing the stress distribution upon simulated application of occlusal forces and assessing its clinical role in marginal bone loss surrounding the implant. Stress exerted on the cortical and cancellous bones of three different platform type implants (URIS, TSIII, and Astra EV) were analyzed using finite element analysis (FEA). A load of 150 N was applied at 0°, 45°, and 90° angles to the long axis of each implant, and marginal bone loss in the implanted URIS fixtures (blood pocket designed platform) after immediate and delayed loading was measured. FEA showed that the stress generated on the fixture upon loading of the URIS implant was lower than that of the other two implants. The URIS implant also exerted the lowest stress on the cortical bone upon application of vertical pressure at an angle of 0° to the long axis of the fixture. The mean marginal bone loss in the alveolar bone was 1.01±0.33 mm and 0.46±0.30 mm upon immediate and delayed loading, respectively. FEA also indicated that implants with blood pocket designed platforms exhibited better stress distribution in the implant fixture and cortical bone under vertical pressure when compared to the fixtures of other designs. The marginal bone loss observed one year after loading of the URIS implant in the current study was lower than that reported previously.

KCI등재

저자 : Hee-yeoung Jung , Junyeong Lee , Dae-seung Yang , Jin-yong Cho , Jaeyoung Ryu

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 46권 2호 발행 연도 : 2022 페이지 : pp. 87-90 (4 pages)

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Pleomorphic adenoma is the most common tumor associated with the salivary gland. These tumors are derived from a mixture of ductal and myoepithelial elements and rarely develop in the jawbones. Regardless of the site of origin, pleomorphic adenoma presents as a painless, firm, and slow-growing mass, which is often misdiagnosed as an odontogenic cyst when located in the tooth-bearing areas of the jaws.

KCI등재

저자 : Seon-ki Lee

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 46권 2호 발행 연도 : 2022 페이지 : pp. 91-98 (8 pages)

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Pathologically progressive dental wear can cause dentin damage and pulp disease; it can even lead to tooth loss. The patient described herein, a 60-year-old male, had a decrease in vertical dimension due to severe abrasion of his remaining teeth and loss of his posterior teeth. The pattern of wear and its causes were evaluated, after which an appropriate vertical dimension and a repeatable centric relation position were considered. A full-mouth rehabilitation by increasing the vertical dimension was planned for the patient. His posterior bite support, wear history, facial features, interocclusal distance, and pronunciation were evaluated to determine the appropriate intermaxillary relationship and vertical elevation. Afterwards, full-mouth rehabilitation was completed using a monolithic zirconia prosthesis. The patient adapted well to the increased vertical dimension and the final prosthesis, had no complaints, and was aesthetically satisfied.

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KCI등재

저자 : Yong Yoon , Hyerin Kim , Jae Mok Lee

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 99-106 (8 pages)

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This study aimed to investigate the expression levels of antioxidative enzymes such as superoxide dismutase 3 (SOD3), heme-oxygenase (HO), and myeloperoxidase (MPOs), which are known to be associated with oxidative stress induction in chronic inflammatory conditions like periodontitis. We compared the expression levels of SOD3, HO, and MPO in the periodontal tissues of healthy individuals with those in the periodontal tissues of chronic periodontitis patients. The expression levels of SOD3, HO, and MPO were determined by Western blot technique, and the data were statistically analyzed. The expression levels of SOD3 and HO increased in periodontitis patients compared with those in healthy controls, and the degree of increase was dependent on the severity of periodontitis (p<0.05). In contrast, the expression level of MPO was lower in the periodontal tissues of healthy controls than that in the periodontal tissues of periodontitis patients (p<0.05). SOD and HO are involved in oxidative stress via antioxidative activity, and MPO is involved in oxidative stress via peroxidative activity. Hence, these findings suggest that antioxidative activity depends on the severity of inflammation. In conclusion, SOD3, HO, and MPO may play a role in oxidative stress-induced periodontitis, and these three factors may be related to the severity of inflammation. These factors are expected to be applied to the diagnosis and treatment of periodontitis through more comprehensive studies.

KCI등재

저자 : Ho Kyung Yu , Jiyoung Park , Young-hoon Kang , Hee Bin Park , Sung Il Bae , Soo Hee Lee , Seong-ho Ok , Sang-ho Jeong , Miyeong Park

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 107-114 (8 pages)

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Epistaxis often is caused by nasal mucosal damage and vascular injury after nasotracheal (NT) intubation. Bupivacaine constricts blood vessels at low concentrations and dilates them at high concentrations. In this study, in which we evaluated the effects of intranasal packing with bupivacaine to prevent epistaxis and pain induced by NT intubation, we classified 180 patients into three groups: an untreated group (n=60), a group pretreated with epinephrine (n=60), and a group pretreated with bupivacaine (n=60). In all groups, we used nasal Ring-Adair-Elwyn tubes with the thermosoftening method for NT intubation. We classified the degree of epistaxis as Grade 0 (none), Grade 1 (mild), Grade 2 (moderate), or Grade 3 (severe). We assessed postoperative visual analog scale (VAS) scores for nose pain in the recovery room. We found that the incidence of epistaxis in the group pretreated with bupivacaine was significantly less than was that of the untreated group (55% vs. 35%, p<0.05). Univariate logistic regression analysis revealed a reduction in epistaxis with bupivacaine nasal packing (odds ratio=0.689, 95% confidence interval=0.478, 0.992). Postoperative VAS scores after 30 minutes in the nasal area were lower in the group pretreated with bupivacaine than were those in the untreated group or the group pretreated with epinephrine (p<0.05). Therefore, we conclude that nasal packing with bupivacaine can help reduce epistaxis and nasal pain more effectively as compared to cases without pretreatment with this anesthetic.

KCI등재

저자 : Si Young Lee

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 115-118 (4 pages)

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Oral viridans streptococcus is the most common bacterial species present in human dental plaque. The Rapid ID 32 Strep (bioMerieux, Marcy-l'Etoile, France) test system allows for the identification of most streptococci within 4 hours. The aim of this study was to evaluate the reliability of this test in identifying isolates of α-hemolytic oral streptococci in human dental plaque and compare it with that of the 16S rRNA sequencing method. A total of eighty-five α-hemolytic streptococcal isolates were identified using 16S rRNA gene sequencing and Rapid ID 32 Strep. The Rapid ID 32 Strep method correctly identified 80% of the species and 87% of the streptococcal groups but failed to accurately identify five isolates (three S. cristatus, one S. australis, and one S. tigurinus).

KCI등재

저자 : Hyun-jeong Park , Ji Hoo Kim , Ji-won Ryu

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 119-124 (6 pages)

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For the diagnosis of oral candidiasis, the most commonly used method is culturing the Candida strains acquired by rubbing the mucous membrane in the mouth using a sterile cotton swab on the medium. This study was conducted to compare the accuracy of Potato Dextrose Agar (PDA) and chromogenic CHROMagar media in diagnosing oral candidiasis. This study included patients diagnosed with oral candidiasis who visited Chosun University Dental Hospital between January 1, 2018 and February 28, 2019. All study subjects were tested using the culture method to diagnose oral candidiasis. For statistical analysis of this study, IBM SPSS version 25.0 (IBM Co., Armonk, NY, USA) was used. Cross analysis was used to compare the diagnostic accuracy of PDA and CHROMagar media as well as treatment effects and diagnoses using each medium. When diagnosed using PDA medium, the sensitivity was high at 91.3% but the specificity was relatively low at 46.0%. It was observed that the accuracy of the diagnosis method using PDA medium was relatively lower than that of the diagnosis method using CHROMagar medium. But the treatment effects in groups diagnosed with PDA medium were higher than those diagnosed with CHROMaga medium. According to the results of our study, CHROMagar medium is recommended for the diagnosis of oral candidiasis; as an alternative, a nonselective medium, such as PDA medium, can be used for the diagnosis of oral candidiasis.

KCI등재

저자 : Young-eun Kwon , Seo-young An

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 125-134 (10 pages)

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The identification of radiopacities in the facial region is important during routine radiographic examination. This study analyzed the radiographic findings of filler-related radiopacities (FRR) and multiple miliary osteomas (MMO) in this region using dental radiographs. Image data were obtained from patients at the Kyungpook National University Dental Hospital. Cone-beam computed tomography (CBCT)/CT data of patients with multiple facial radiopacities on plain images (panoramic and periapical images; 16 FRR and 224 MMO) were collected and matched with the corresponding conventional images. In the CBCT/CT images, the FRRs were mainly observed in the cheek (87.5%) and retromaxillary space (68.8%) whereas the MMOs were mostly located in the superficial areas of the cheek (81.3%) and chin (36.2%). The statistical differences were only in the retromaxillary space (p<0.05). The FRRs were mostly ring-shaped (68.8%) or nodular in appearance (56.3%), whereas the MMOs presented as calcific foci (96.4%). The results of the chi-square test revealed statistically significant differences in the detection of FRRs and MMOs in the panoramic images (p<0.05), but not the periapical images. The FRRs were located in the deeper layers of the skin and were more diverse in appearance than the MMOs. Moreover, FRRs were better identified than MMO in the panoramic images. Dentists should have knowledges about image findings of FRRs and be able to differentiate them from MMOs based on the radiographic images.

KCI등재

저자 : Soobin Lee , Sung-joon Kim , Chan-woo Jo , Jaeman Woo

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 135-142 (8 pages)

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Advancements in medical care resulted in increase of average longevity. In turn, people have become more concerned about health, oral health, and quality of life. Such change has led to need for systematic and prevention-oriented healthcare service. This study aimed to provide preliminary information on the level of familiarity with national health insurance (NHI) benefits by the general public in order to help make decisions regarding education and advertisement policies. 337 adults who visited Korea Association of Health Promotion health examination center in Jeju were given self-administered surveys regarding personal oral health status, familiarity with NHI-covered procedures, and personal interest in oral health, and the results were analyzed statistically. 83.4% answered 'Yes,' to awareness of NHI coverage of dental scaling. Most people answered 'Yes' to awareness of the fact that NHI-covered dental scaling begins at 19 years of age, while relatively few people were familiar with NHI-covered denture and dental implant procedures. According to this study, many respondents were still not familiar with the expanded NHI coverage. Especially the younger population lacked information on NHI-covered denture and dental implant, indicating need for public education and advertisements. In order to efficiently advertise and educate, joint effort by the government and medical facilities is recommended. Utilization of social media in addition to the more traditional mass media should be effective in conveying information to the younger population. Age-appropriate education for policy change and coverage expansion regarding NHI-covered denture and dental implant is also advised.

KCI등재

저자 : Min-keun Kim , Jin-woo Han , Kwang-jun Kwon , Young-wook Park , Jin-hyung Shim

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 143-149 (7 pages)

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Facial asymmetry is difficult to correct mainly because of the large volume of implant required for reconstruction, which is hard to estimate. Computer-aided surgical planning using three-dimensional (3D)-printed implants is developing rapidly, with promising clinical results being reported in reconstructive, orthognathic, and other surgical fields. A 54-year-old male patient presented with facial asymmetry caused by fibular free flap displacement. This was surgically corrected using a customized, 3D-printed polycarprolactone/beta tricalcium phosphate scaffold. The implant fit well and was easily fixed to the right mandibular angle area, resulting in an improvement in the facial contour of the patient. Throughout the follow-up period, the PCL/β-TCP implant was detected using an ultrasonic device and remained without volumetric change. There was also no wound dehiscence or implant displacement. Thus, a patient-specific 3D-printed biodegradable scaffold can effectively facilitate surgical correction of facial asymmetry. However, facial contour sequelae, stability, and resorption must be assessed over a long-term follow-up period.

KCI등재

저자 : Jae-hong Lee , Seong-nyum Jeong

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 150-155 (6 pages)

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Verruciform xanthoma is a benign growth found on the oral mucosa. Clinically, verruciform xanthoma is an asymptomatic lesion, and depending on the amount of keratin present on the surface of the oral mucosa, it can appear as a reddish-gray papillary, flat lesion or a slightly raised, rough lesion. The verrucous structure and exophytic properties of these lesions are similar to those of malignant tumors; therefore, histopathological assessment is required for an accurate and definitive diagnosis. The purpose of this case report is to present the clinical, histological, and deep learning-based assessments and treatment of verruciform xanthoma of the maxillary palatal gingiva.

KCI등재

저자 : Jung Woo , Hyun-jun Park , Hee-jung Kim , Joo-hun Song

발행기관 : 조선대학교 치의학연구원 간행물 : Oral Biology Research (OBR) 45권 3호 발행 연도 : 2021 페이지 : pp. 156-163 (8 pages)

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The disadvantages of the traditional approach for fabricating dental implant prostheses have been addressed via oral scanning and the use of computer-aided design/computer-aided manufacturing systems. The use of an intraoral scanner can eliminate the need for impression materials and impression trays, which are inconvenient for patients, particularly those with limited mouth opening or an overly sensitive gag reflex. Moreover, it can reduce the additional costs of fabricating, storing, and handling the patients' models. This case report describes the fabrication of a posterior implant prosthesis using double scanning technique, which produced satisfactory results both esthetically and functionally. The double scanning technique produces a more accurate image of the target region by overlapping data from both intraoral and extraoral scans. Therefore, it can address the disadvantages of both traditional and digital impressions, reduce patient discomfort, and decrease the incidence of remakes, which can arise due to potential errors during the fabrication process.

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