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대한피부과학회지 update

Korean Journal of Dermatology

  • : 대한피부과학회
  • : 의약학분야  >  피부과학
  • : KCI등재
  • : SCOPUS
  • : 연속간행물
  • : 월간
  • : 0494-4739
  • : 2713-7627
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수록정보
51권7호(2013) |수록논문 수 : 22
간행물 제목
59권8호(2021년 09월) 수록논문
최근 권호 논문
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KCI등재 SCOPUS

1단기간 피부과 의료봉사와 세계보건: 기후 변화 분석을 통한 후향적 연구

저자 : 함민석 ( Min Seok Ham ) , 김대연 ( Dae Yeon Kim ) , 김대현 ( Dai Hyun Kim ) , 서수홍 ( Soo Hong Seo ) , 안효현 ( Hyo Hyun Ahn )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 581-586 (6 pages)

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Background: The coronavirus disease pandemic has directly impacted global health. In developing countries, health service problems are more serious because of the lack of healthcare infrastructure. In this situation, if medical needs could be predicted, it would be helpful to bridge the medical gap with the provision of appropriate medical support.
Objective: The aim of this study was to evaluate the association between climate change and skin diseases in developing countries to better prepare for medical missions.
Methods: From 2012 to 2016, except for 2014, we visited a mission site located in Luzon, Philippines, every July. We retrospectively reviewed 499 patient data as well as weather information.
Results: The total number of patients decreased each year. The climate change analysis using Pearson correlation showed that the temperature and ultraviolet index tended to increase every year (r2=0.99, 0.93, respectively; p< 0.05). Conversely, humidity and rainfall decreased (r2=-0.99, -0.96, respectively; p<0.05). The Cochran-Armitage test showed that the rate of infectious skin disease diagnoses decreased every year compared to that of eczematous diseases.
Conclusion: The total number of patients decreased by approximately 50% during medical service. We believe that the improvement in living standards and hygiene through continuous medical support has influenced the change in the incidence of skin diseases. Climate change was also thought to have affected the rate of skin disease diagnoses; in fact, the rate of infectious disease diagnoses tended to decrease compared to that of eczematous diseases. This analysis would be helpful for preparing for medical support. (Korean J Dermatol 2021;59(8):581∼586)

KCI등재 SCOPUS

2화농성 한선염 환자의 병변 평가와 중증도 설정을 위한 초음파 검사의 유용성

저자 : 김고은 ( Ko Eun Kim ) , 정재영 ( Jae Yeong Jeong ) , 박병근 ( Byeong Geun Park ) , 김일환 ( Il-hwan Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 587-595 (9 pages)

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Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by recurrent abscesses, nodules, and fistulous tracts. Recently, novel staging systems, including sonographic scoring system of hidradenitis suppurativa (SOS-HS), have been widely introduced in HS.
Objective: To assess the efficacy of SOS-HS compared with Hurley staging and modified sartorius scoring (MSS) system and determine the necessity of ultrasound evaluation.
Methods: A radiologist performed an ultrasound evaluation, and three dermatologists reviewed the images and videos. Clinical characteristics, including staging and demographic data, were recorded by three dermatologists. The correlation of each staging system and the significance of vascularity (Doppler mode) and lesion depth on sonography were statistically analyzed.
Results: Among the 46 patients, 34.8% were classified as stage 1 and 3, and 30.4% were classified as stage 2 in the SOS-HS system, which was statistically higher than the Hurley staging (p<0.0005). MSS score increased according to the SOS-HS stages (p<0.0005, p=0.001). Vascularity and depth of involvement also increased with SOS-HS and Hurley staging.
Conclusion: Sonographic examination can be applied in HS severity assessment and documentation of the clinical characteristics of each lesion in detail. Special tools, such as Doppler mode and depth assessment, can also be useful in HS evaluation. (Korean J Dermatol 2021;59(8):587∼595)

KCI등재 SCOPUS

3최근 8년간(2012∼2020) 단일기관 피부과에서의 연조직염 입원환자에 대한 임상적 고찰

저자 : 정홍필 ( Hong Pil Jeong ) , 김창일 ( Chang Il Kim ) , 허은필 ( Eun Phil Heo ) , 고재완 ( Jae Wan Go )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 596-603 (8 pages)

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Background: Cellulitis is one of the most common infectious skin diseases treated by hospitalization, and presents with various clinical features and treatment responses. Therefore, more detailed analysis on this condition is required.
Objective: To investigate the clinical characteristics of cellulitis among dermatology inpatients in a single center.
Methods: We retrospectively reviewed the medical records of 84 patients hospitalized with cellulitis between January 2012 and August 2020. We analyzed the differences by dividing them into <60-year-old and >60-year-old age groups.
Results: The average age of the 84 inpatients in this study was 48.8 years with the peak incidence in fifties. Cellulitis was most prevalent in the calf (39.8%). Erythrocyte sedimentation rate (ESR) and risk factors such as obesity and smoking had positive correlations with duration of hospital stay (p<0.05). There was no significant difference in duration of hospital stay between those administered first-generation cephalosporin and other antibiotics.
Conclusion: Our data showed that ESR, obesity, and smoking were correlated to the hospitalization periods. In particular, it showed positive correlation of C-reactive protein and ESR with duration of hospital stay in those below the age of 60 years. (Korean J Dermatol 2021;59(8):596∼603)

KCI등재 SCOPUS

4스티븐스 존슨 증후군 및 독성표피괴사융해증 88예의 임상적 고찰

저자 : 홍정연 ( Jeong Yeon Hong ) , 정의현 ( Euy Hyun Chung ) , 양나경 ( Na Gyeong Yang ) , 김재윤 ( Jae Yun Kim ) , 허남훈 ( Nam Hun Heo ) , 이설희 ( Sul Hee Lee ) , 김정은 ( Jung Eun Kim ) , 이성열 ( Sung Yul Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 604-610 (7 pages)

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Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially fatal acute hypersensitivity reactions that involve the skin and mucous membranes. Because they are relatively rare diseases, it is difficult to obtain well-organized epidemiological data. The clinicodemographic characteristics, culprit drugs, and factors related to disease prognosis may vary.
Objective: To identify the characteristics of SJS/TEN by investigating patient clinicopathological characteristics, laboratory findings, suspected drugs, and mortality through a retrospective study using medical record data.
Methods: The clinical records of patients diagnosed with SJS/TEN between February 2009 and February 2019 at three medical institutions of Soonchunhyang University were retrospectively reviewed. Data pertaining to sex, age, history, suspected drugs, latent period, laboratory findings, and mortality were collected, and their correlations were analyzed.
Results: We identified SJS/TEN in 88 patients. Among the probable causative agents, antibiotics were the most common (29 cases, 33.0%), followed by nonsteroidal anti-inflammatory drugs (NSAIDs) in 20 cases (22.7%). The period between drug administration and symptom onset varied with the causative agent. Patients who died had high SCORTEN scores. In addition, hypertension, diabetes, renal failure, and cardiac disease had a statistically significant association with high SCORTEN.
Conclusion: Antibiotics, NSAIDs, antiepileptics and allopurinol were the most commonly implicated drugs in our retrospective study. There was a significant correlation between comorbidities. Because SJS/TEN is a life-threatening condition, early recognition of the suspected drug are important. The results of this study may provide insights that aid in the early diagnosis and prediction of disease outcomes of SJS/TEN in the Korean population. (Korean J Dermatol 2021;59(8):604∼610)

KCI등재 SCOPUS

5외국인 어업 노동자의 바닷물 첩포검사에 대한 보고

저자 : 서지민 ( Ji Min Seo ) , 윤소연 ( So Yeon Yoon ) , 구하예린 ( Ha Yeh Rin Koo ) , 김경문 ( Gyong Moon Kim ) , 유동수 ( Dong Soo Yu ) , 이영복 ( Young Bok Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 611-617 (7 pages)

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Background: Occupational allergic contact dermatitis accounts for about half of all occupational skin diseases. Patch testing is essential for establishing a diagnosis of occupational allergic contact dermatitis. To date, allergic contact dermatitis caused by seawater has rarely been reported.
Objective: The aim of this study was to investigate the patch test results of seawater in foreign maritime workers.
Methods: We retrospectively reviewed the clinical photos and medical records of patients who underwent the patch test with the Korean standard series and sea-water at Uijeongbu St. Mary's Hospital and St. Vincent's Hospital from January 2017 to August 2020.
Results: A total of 26 patients were enrolled in the study. All patients were men with a median age of 26.5 years. Twenty-five patients were Sri Lankan, and 25 patients (96.2%) showed a positive reaction to seawater. Patients showed positive reactions with multiple allergens (average: 4), and the positive rates were higher than those reported in previous studies. Atypical reactions, such as pricking patterns or erosive patches, have been observed. A marked erosive reaction was observed even at the site without allergen attachment in a patient who showed a negative reaction to seawater.
Conclusion: These results suggest the possibility of artificially inducing positive reactions to seawater in maritime workers. Therefore, it is necessary to identify atypical reactions and confirm the relationship between positive reactions and medical history when judging contact dermatitis with unknown substances such as seawater. This study emphasizes education on the standardization of the reading of results. (Korean J Dermatol 2021;59(8):611∼617)

KCI등재 SCOPUS

6조갑진균증에서 병리조직검사의 진단적 가치 및 Periodic Acid-Schiff와 Gomori's Methenamine Silver 염색의 민감도 비교

저자 : 백가연 ( Gayun Baek ) , 구태한 ( Taehan Koo ) , 이동훈 ( Donghoon Lee ) , 강현지 ( Hyun Ji Kang ) , 김민수 ( Min-soo Kim ) , 김영혜 ( Younghye Kim ) , 주민숙 ( Mihn-sook Jue )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 618-623 (6 pages)

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Background: A direct potassium hydroxide (KOH) smear is used to diagnose onychomycosis despite its broad sensitivity range. For a more accurate diagnosis, histopathologic examination can be used and consistently show high sensitivity.
Objective: We investigated the value of histopathologic examination of the nail plate as a diagnostic tool for onychomycosis. We proposed effective routine diagnostic staining to compare sensitivity between periodic acid-Schiff (PAS) and Gomori's methenamine silver (GMS) staining.
Methods: This retrospective study was conducted from January 1, 2019 to May 31, 2020, and included 97 patients who showed negative results on direct KOH smear but had clinical manifestations that implied onychomycosis. We performed nail plate biopsy and PAS or GMS staining to identify fungal hyphae missed in the direct KOH smear. Sensitivity comparison between PAS and GMS was performed in co-stained samples.
Results: Among 97 patients with 102 cases, 55 cases (53.9%) of onychomycosis were confirmed by histopathologic examination. A total of 68 patients (70.1%) had a previous medical history of antifungal agents within previous six months. PAS and GMS staining were concurrently performed in 73 cases, and onychomycosis was confirmed in 41 cases. The sensitivity of PAS was 100% (41/41), while that of GMS was 87.8% (36/41); this difference was not significant.
Conclusion: This study suggests that histologic examination of the nail plate is an effective tool to diagnose onychomycosis and can be performed with a direct KOH smear. Two staining methods, PAS and GMS, are recommended for concurrent performance to enhance the identification of fungal hyphae. (Korean J Dermatol 2021;59(8):618∼623)

KCI등재 SCOPUS

7주사 환자의 임상적 고찰 및 주사의 진단 분류 체계의 비교에 대한 연구

저자 : 임준수 ( Joon Soo Lim ) , 권은선 ( Eun Sun Kwon ) , 명기범 ( Ki Bum Myung ) , 정승현 ( Seung Hyun Cheong )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 624-633 (10 pages)

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Background: Rosacea is a common chronic inflammatory skin disease, which primarily affects the central face. In 2002, the National Rosacea Society (NRS) committee developed the first diagnostic criteria for rosacea, based on its subtypes. The revised classification in 2017 prompted a proposal to transit from a subtyping to a phenotyping approach, reflecting current insights into rosacea pathogenesis, pathophysiology, and management.
Objective: This study aimed to elucidate the clinical features of rosacea and compare two diagnostic criteria in rosacea patients.
Methods: We performed a clinical study on 100 patients with rosacea diagnosed according to the 2002 NRS criteria. The age, sex, clinical features, subtypes, severity, and predisposing factors were evaluated using the questionnaire. In addition, we compared the 2002 and 2017 criteria, and evaluated patients if they met the revised criteria.
Results: According to the 2002 NRS classification, the erythematotelangiectatic type (88.0%) was the most frequent, followed by the papulopustular (43.0%), ocular (13.0%), and phymatous (6.0%) types. There were 44 overlapping cases, including 38 cases with 2 subtypes mixed and 6 cases with three subtypes. Six patients were diagnosed with rosacea using the 2002 NRS criteria but they did not satisfy the revised 2017 criteria.
Conclusion: We found that the diagnostic features of the 2002 criteria are too ambiguous for the diagnosis of rosacea. Therefore, we recommend that dermatologists recognize the necessity of a transition from a subtyping to a phenotyping approach, according to the 2017 criteria for the diagnosis of rosacea. (Korean J Dermatol 2021;59(8): 624∼633)

KCI등재 SCOPUS

8Histopathological and Immunohistochemical Differentiation between Psoriasis and Seborrheic Dermatitis of the Scalp: Based on Langerin and CD1a

저자 : Ji Ha Yoon , Hye Rim Park , Eun Joo Park , Kwang Joong Kim , Kwang Ho Kim

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 634-639 (6 pages)

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Background: Psoriasis and seborrheic dermatitis are difficult to distinguish if the lesion is localized to the scalp.
Objective: To validify the use of langerin and CD1a as markers of Langerhans cells to distinguish scalp psoriasis from seborrheic dermatitis.
Methods: We retrospectively evaluated 25 seborrheic dermatitis cases and 17 psoriasis cases diagnosed at a tertiary medical center in Korea from 2010 to 2019. The histopathological features and expression of CD1a and langerin were analyzed by dermato-pathologists.
Results: Hyperkeratosis, parakeratosis, and the presence of neutrophils in the parakeratotic mound were observed more frequently in the psoriasis group than in the seborrheic dermatitis group (p=0.016, p=0.027, and p=0.021, respectively). Other features examined did not show statistically significant differences. Dermal expression of langerin occurred more frequently in the psoriasis group than in the seborrheic dermatitis group (76.5% vs. 36.0%, p=0.010). Additionally, stronger CD1a dermal expression was observed in the psoriasis group than in the seborrheic dermatitis group (p=0.049), although the difference in overall dermal CD1a expression regardless of strength was not significant. In contrast, the epidermal expressions of CD1a and langerin did not show significant differences. Similarly, the follicular expressions of CD1a and langerin did not demonstrate significant differences.
Conclusion: In this retrospective study, histopathological findings that favored psoriasis over seborrheic dermatitis included hyperkeratosis, parakeratosis, and the presence of neutrophils in the parakeratotic mound. The use of Langerhans cells, CD1a, and langerin as markers could help distinguish scalp psoriasis from seborrheic dermatitis. (Korean J Dermatol 2021;59(8):634∼639)

KCI등재 SCOPUS

9아랫입술에 발생한 육종성 편평세포암

저자 : 남경화 ( Kyung-hwa Nam ) , 이일재 ( Il-jae Lee ) , 이상경 ( Sang-kyung Lee ) , 박진 ( Jin Park ) , 김한욱 ( Han-uk Kim ) , 윤석권 ( Seok-kweon Yun )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 640-643 (4 pages)

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Sarcomatoid squamous cell carcinoma (SSCC) is a rare malignancy with distinct carcinomatous and sarcomatous features. SSCCs involving the lung, esophagus bladder, and skin have been reported as rare case reports. It may also occur infrequently in the oral region. Moreover, the lower lip is still one of the rare sites, and such a case has not been reported in Korean literature. An 82-year-old man presented an exophytic protruding, huge, warty crusted lesion on the entire lower lip. The lesion started as a small, tender, erosive papule and suddenly enlarged in recent months. His medical history was unremarkable. A biopsy revealed atypical squamous and sarcomatous components with transition zones between the two cell types. These two cell types also showed characteristic immunohistochemical features. Based on these findings, the lesion was diagnosed as SSCC. The study, including positron emission tomography-computed tomography, showed no metastasis. We recommended surgical excision, but the patient refused therapy. (Korean J Dermatol 2021;59(8):640∼643)

KCI등재 SCOPUS

10Cutaneous Adverse Events of Anti-Programmed Cell Death Receptor-1 Antibody: Two Case Reports and a Literature Review

저자 : Joon Soo Lim , Hyun Hee Kim , Eun Sun Kwon , Ki Bum Myung , Seung Hyun Cheong

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 59권 8호 발행 연도 : 2021 페이지 : pp. 644-648 (5 pages)

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The introduction of immune checkpoint inhibitors, including anti-programmed cell death receptor-1 antibodies (anti-PD-1 Ab), such as nivolumab and pembrolizumab, represents a major breakthrough in cancer therapy. The PD-1 pathway inhibits T cell activation, maintaining a normal and balanced immune response. Anti-PD-1 Ab induces T cell activity by inhibiting the suppressive effect of PD-1 signaling on T cells. Excessive stimulation of T cells represents a potential mechanism for multiple skin lesions. To the best of our knowledge, reports on cutaneous adverse effects during treatment with anti-PD-1 Ab are limited in the dermatological literature of Korea. Herein, we report two rare cases of nivolumab-induced lichenoid drug eruption and pembrolizumab-induced psoriasis. (Korean J Dermatol 2021;59(8):644∼648)

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KCI등재SCOUPUS

1원저 : 갑상선 수술 후 발생한 비대흉터와 켈로이드에서 스테로이드 병변내 주사 단일요법과 스테로이드 병변내 주사 및 냉동치료 병용요법에 관한 비교 연구

저자 : 박지혜 ( Ji Hye Park ) , 박지윤 ( Ji Youn Park ) , 장용현 ( Yong Hyun Jang ) , 이정훈 ( Jung Hoon Lee ) , 소의영 ( Euy Young Soh ) , 김유찬 ( You Chan Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 489-493 (5 pages)

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Background: Various treatment modalities for hypertrophic scars and keloids have been used. However, there is no consensus as to what the optimum approach should be. Most common treatments are corticosteroid intralesional injection (ILI) and cryotherapy as well as combination of these two modalities. To this date, however, there are no prospectively comparative, scar-split studies between steroid ILI monotherapy and combination of steroid ILI and cryotherapy. Objective: The purpose of this article is to investigate and compare the efficacy of steroid ILI monotherapy and the combination of steroid ILI and cryotherapy. Methods: Eighteen women who had thyroid operation scars were recruited. Patients received steroid ILI with cryotherapy on the right half, and steroid ILI monotherapy on the left half of the scar. Patients were treated for four sessions with three weeks of intervals. Subjects were evaluated on their scar status with the modified Vancouver scar scale (MVSS) and scar redness by using colorimeter at baseline and every visit day. Results: After four treatment sessions, MVSS was significantly improved on both sides of scar. Significant improvement was observed after one treatment session on the right half, and after two treatment sessions on the left half. There was no significant difference between left and right side after four sessions of treatment. The scar redness of both sides of scar showed no significant differences between the baseline and at the end of the study. Conclusion: Both corticosteroid ILI with cryotherapy and corticosteroid ILI monotherapy are effective treatment modalities for hypertrophic scars. However, the results of the present study suggest that a combination therapy might lead to more rapid improvements. (Korean J Dermatol 2013;51(7):489∼493)

KCI등재SCOUPUS

2원저 : 지루각화증과 유사한 임상 양상을 나타낸 안면부 병변의 임상 및 병리조직학적소견에 대한 연구

저자 : 김흥열 ( Heung Yeol Kim ) , 김한수 ( Han Soo Kim ) , 조은별 ( Eun Byul Cho ) , 박은주 ( Eun Ju Park ) , 김광호 ( Kwang Ho Kim ) , 김광중 ( Kwang Joong Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 494-500 (7 pages)

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Background: The most of typical seborrheic keratoses (SKs) can be clinically differentiated with ease from other dermatoses. However, its differential diagnosis can sometimes be difficult and recently reported cases clinically suggest that SKs with the skin biopsy result being some other diseases can bring on the need for further evaluations. Objective: The aim of this study is to examine the diagnostic yield in submitting clinically diagnosed SKs which showed single discoid lesions of the face for routine microscopic examinations. Methods: We conducted a retrospective review of cases for histological examinations with a clinical diagnosis of SKs or with a differential diagnosis that includes SKs which shows single discoid lesion of the face. A total of 94 pathology reports containing a diagnosis of SKs in the clinical information field were identified. The accuracy of the clinical diagnosis and clinic histopathological correlations were studied. Results: In this study, 45.7% of patients was clinically assumed to have SKs but turned out to be some other diseases according to the histopathology test results - a total of 19 cases (44.2%) with some considered to be precancerous (actinic keratosis 25.6%, benign lichenoid keratosis 16.3% or cancerous (basal cell carcinoma 9.3%, squamous cell carcinoma 4.7%). Conclusion: Lesions suggested to be SKs need more examinations and lesions of atypical clinical appearances which cannot completely exclude the possibility of precancerous or malignant lesions are strongly recommended for skin biopsies. (Korean J Dermatol 2013;51(7):494∼500)

KCI등재SCOUPUS

3원저 : 5년간 경험한 소아 원형 탈모증 환자의 임상적 고찰(2007∼2012)

저자 : 손현옥 ( Hyun Ok Son ) , 노병인 ( Byung In Ro ) , 조한경 ( Han Kyoung Cho )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 501-506 (6 pages)

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Background: Alopecia areata (AA) is a non-scarring, autoimmune, inflammatory hair loss on the scalp and/or body. This disease affects both adults and children but there are limited data on AA in children than AA in adults. Objective: The purpose of this retrospective study is to evaluate the clinical characteristics, disease associations and psychosomatic dynamics of pediatric AA for the past 5 years. Methods: A retrospective study was performed on 120 out-patients under 14 years old who are diagnosed as alopecia areata in the department of dermatology from March, 2007 to February, 2012. Results: The proportion of pediatric group in total alopecia areata was 20.2% (120/595). According to clinical records, the alopecia areata were of 111 patients (79.9%) followed by those with alopecia universalis (4 patients; 2.8%) and alopecia totalis (5 patients; 3.6%). The ratio of males (57 patients; 47.5%) to females (63 patients; 52.5%) was 1 : 1.11. Alopecia areata was seen most frequently in the school age group (69 patients; 57.5%) and the duration period was less than one year in most cases (79.2%). Family history of alopecia areata was observed in 10.8% (13/120). The only child or eldest child being overloaded with homework and has deficient parent-child relationships including familial discord was accounted as the most susceptible group. A multiple bald patch was 51.4% in alopecia areata and the most common associated disease was atopic dermatitis (26 patients; 21.7%). Conclusion: We observed several clinical features of the pediatric AA, including epidemiology, clinical characteristics and disease associations. This study provided useful data for future research regarding AA in children. (Korean J Dermatol 2013;51(7):501∼506)

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4원저 : 파종 대상포진의 역학 및 임상양상

저자 : 김효진 ( Hyojin Kim ) , 강정난 ( Jeong Nan Kang ) , 설정은 ( Jeong Nan Kang ) , 서종근 ( Jong Keun Seo ) , 성호석 ( Ho Suk Sung )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 507-512 (6 pages)

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Background: There have been several studies about herpes zoster in the Korean dermatological literatures. However, there are few studies reported on disseminated herpes zoster. Objective: The aim of this study is to determine the epidemiology and clinical features of the disseminated herpes zoster as compared with herpes zoster. Methods: The authors retrospectively reviewed the medical records on 14 cases of disseminated herpes zoster and 402 cases of herpes zoster at the Department of Dermatology Busan Paik hospital during the 3 years from 2010 to 2012, and if necessary, telephone interviews were executed. Results: The rate of new disseminated herpes zoster outpatients at our dermatology clinic was 0.11% with the mean age of 67.7 years and the males to females ratio was 2.5. The most frequent involved dermatome was the lumbar (42.9%) area. The rate of patients with underlying diseases or immunosuppression, the rates of postherpetic neuralgia and the frequency of narcotic analgesics uses were significantly higher in disseminated herpes zoster as compared with herpes zoster. The patient treatment satisfaction was significantly higher in herpes zoster as compared with disseminated herpes zoster. Conclusion: These results demonstrated that the disseminated herpes zoster is associated with higher rates of underlying diseases, immunosuppression, frequent incidences of postherpetic neuralgia, more uses of narcotic analgesics and lower patient treatment satisfactions as compared with herpes zoster. (Korean J Dermatol 2013; 51(7):507∼512)

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5원저 : 보우선의 임상적 고찰

저자 : 이경진 ( Kyung Jin Lee ) , 정화영 ( Hwa Young Jung ) , 이영복 ( Young Bok Lee ) , 오신택 ( Shin Taek Oh ) , 조백기 ( Baik Kee Cho ) , 박현정 ( Hyun Jeong Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 513-522 (10 pages)

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Background: Beau`s lines are transverse furrows of the nail plates that can be caused by various conditions. Because the clinical manifestations of Beau`s lines tend to depend on its causes, the clinical manifestations may provide diagnostic clues of causative or underlying diseases. Objective: This study is conducted to provide a better understanding of Beau`s lines and to give dermatologists diagnostic clues from assessment of its morphological patterns. Methods: In order to investigate the clinical characteristics and patterns of Beau`s lines according to its clinical manifestations, a retrospective study was being performed. A total of 150 patients with Beau`s lines who visited the nails clinic of our hospital from January 1, 2006, to September 30, 2010, were included. Results: The group of patients with Beau`s lines consisted of 78 males (52%) and 72 females (48%). The onset age ranged from 1 to 82 years old. The most frequently involved fingernail was the right thumb nail. In this study, causes of Beau`s lines were grouped into eight categories: idiopathic, traumatic, nail/skin disease, systemic illness, bone marrow transplantation, chemotherapy, nail infection, and others. Idiopathic cause was observed the most frequently. The pattern of Beau`s lines was symbolized in each patient and was depicted in a row according to order of frequency. The pattern of N2B2L1D1M2 (Numerous/Multiple/Incomplete/Deep/Broad) was observed overall as the most frequently. The most common pattern in the nail/skin diseases category was N2B1L1D1M2 (Numerous/Single/ Incomplete/Deep/Broad). In the traumatic group, N1B2L1D1M2 (Confined/Multiple/Incomplete/Deep/Broad) was the most frequently observed pattern. Conclusion: This study explored the clinical manifestations of Beau`s lines. In some categories of causes, the morphological patterns showed a tendency to converge. Thus, the morphological patterns can provide certain diagnostic information. (Korean J Dermatol 2013;51(7):513∼522)

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6증례 : 형질세포 귀두염 1예

저자 : 이강모 ( Gang Mo Lee ) , 심지훈 ( Ji Hoon Sim ) , 조문균 ( Moon Kyun Cho )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 523-526 (4 pages)

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Plasma cell balanitis (Balanitis circumscripta plasmacellularis or Zoon`s balanitis) is an idiopathic, benign condition of the glans penis or prepuce. It occurs mostly as a solitary, persistent plaque among middle-aged to older uncircumcised males. It is characterized by chronic, shiny, smooth, red-orange plaques with small, dark red stippling. When the plasma cell balanitis is suspected clinically, diagnosis can be readily confirmed by microscopic examinations of the lesion. Differentiating this lesion from similar lesions such as premalignant, infective and other inflammatory penile lesions is important. The current preferred treatment is circumcision and this disorder can be treated relatively easily by circumcision. We, herein, report an interesting case of plasma cell balanitis on preputial mucosa. (Korean J Dermatol 2013;51(7):523∼526)

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7증례 : 308 nm 엑시머 레이저로 호전된 손발바닥 건선 1예

저자 : 유향석 ( Hyang Suk You ) , 문제호 ( Je Ho Mun ) , 좌승욱 ( Seung Wook Jwa ) , 송마가렛 ( Mar Ga Ret Song ) , 김훈수 ( Hoon Soo Kim ) , 고현창 ( Hyun Chang Ko ) , 김문범 ( Moon Bum Kim ) , 김병수 ( Byung Soo Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 527-530 (4 pages)

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Various modalities have been used for the treatment of psoriasis, including phototherapy. The choice of psoriasis treatment is based on the characteristics of the lesions, locations and amount of involved body surface area. Narrowband ultraviolet (UV) B therapy is a widely used and highly efficient method for psoriasis. But, large areas of unaffected skin may be irradiated along with the psoriatic lesions during phototherapy. The 308-nm excimer laser is a further development of narrowband UVB and was reported to be an effective and safe treatment for localized psoriasis. We experienced an excellent effect without significant adverse reactions of 308-nm excimer laser in a 9-year-old patient with palmoplantar psoriasis who was recalcitrant to oral cyclosporine and topical calcipotriol/ betamethasone treatment. (Korean J Dermatol 2013;51(7):527∼530)

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8증례 : 진성 백혈구 무형성증 환자에서 발생한 조직구양 Sweet 증후군 1예

저자 : 이혜영 ( Hye Young Lee ) , 김준기 ( Jun Ki Kim ) , 이지연 ( Ji Yeoun Lee ) , 김미경 ( Mi Kyeong Kim ) , 윤태영 ( Tae Young Yoon )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 531-535 (5 pages)

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Histiocytoid Sweet syndrome (HSS) is a rare inflammatory disease that has recently been described as a variant of Sweet syndrome. Histopathologically, HSS is characterized by papillary dermal edema with infiltration of histiocytoid cells into the upper dermis. The histiocytoid cells are easily misinterpreted as histiocyte, but in fact, they are immature myeloid cells. To demonstrate cells of myeloid lineage, specific staining must be performed, such as myeloperoxidase (MPO). To date, there are several HSS cases associated with hematological malignancy, drugs, and chronic inflammatory diseases. But, in Korea, only one case has been reported so far. Herein, we report a case of HSS developed in the patient with pure white cell aplasia and review the relevant literature. (Korean J Dermatol 2013;51(7):531∼535)

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9증례 : Blaschko 선을 따라 발생한 선상 반상 아밀로이드증

저자 : 고은정 ( Eun Jung Ko ) , 최선영 ( Sun Young Choi ) , 박귀영 ( Kui Young Park ) , 이갑석 ( Kap Seok Li ) , 김범준 ( Beom Joon Kim ) , 서성준 ( Seong Jun Seo ) , 김명남 ( Meuyng Nam Kim ) , 홍창권 ( Chang Kwun Hong )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 536-538 (3 pages)

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The primary localized cutaneous amyloidosis (PLCA) is classified into three types: macular amyloidosis, lichen amyloidosis, and nodular amyloidosis. Macular amyloidosis is characterized by pruritic, hyperpigmented macules and is most commonly located on the interscapular area. Skin lesion usually shows pigmentation with a reticulated or rippled pattern. We report an unusual case of linear macular amyloidosis along the lines of Blaschko. A 74-year-old male is presented with asymptomatic unilateral linear hyperpigmented macules on his right leg for 20 years. Skin biopsy has revealed eosinophilic cytokeratin-positive globular deposits occupying the dermal papillae. (Korean J Dermatol 2013;51(7):536∼538)

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10증례 : 임신 중 크기가 증가한 피부 상피양 혈관내피세포종: Dermoscopy 소견

저자 : 장민수 ( Min Soo Jang ) , 한상화 ( Sang Hwa Han ) , 박종빈 ( Jong Bin Park ) , 강동영 ( Dong Young Kang ) , 김상태 ( Sang Tae Kim ) , 서기석 ( Kee Suck Suh )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 51권 7호 발행 연도 : 2013 페이지 : pp. 539-543 (5 pages)

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Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor that has been reported in systemic organs and in the skin as a biologically “borderline” neoplasm with intermediate malignant potentials. Skin involvement in EHE is rare, but when present, it occurs most commonly in the upper and lower extremities, presenting as a solitary, slightly painful, soft tissue mass. Skin involvement is often associated with underlying soft tissues or bone tumors. Histopathological study reveals cords and nests of epithelioid endothelial cells in a myxoid or hyalinized background and small intracytoplasmic vacuoles containing red blood cells. There have been no reported cases yet describing the dermoscopic features of EHE. Herein, we describe a young woman who developed cutaneous EHE that enlarged during pregnancy, we provided the dermoscopic findings and a review of the relevant literature. (Korean J Dermatol 2013;51(7):539∼543)

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