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216.73.216.106
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KCI 등재
Lithium tert-Butoxide-catalyzed Hydroboration of Carbonyl Compounds
김재호, Ashok Kumar Jaladi, 김현태, 안덕근
DOI http://dx.doi.org/10.1002/bkcs.11855

We report the successful hydroboration of aldehydes and ketones with pinacolborane using 1?mol % lithium tert-butoxide under ambient conditions. The present protocol was applicable to various aldehydes and ketones, and the corresponding boronate esters and subsequent alcohols were obtained in good to excellent yields. In addition, this high-yielding practical method could be extended to the reduction of ester groups. Under optimized conditions, LiO tBu facilitate the hydroboration of ester groups quantitatively.

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