닫기
216.73.216.28
216.73.216.28
close menu
SCIE
한국재래간장으로 부터 분리한 Bacillus subtilis globigii CCKS - 118 이 생성하는 protease 의 특성 및 작용양상
Characteristics and Action Pattern of Protease from Bacillus Subtilis Globigii CCKS - 118 in Korean Traditional Soy Sauce
최청(Cheong Choi), 최광수(Kwang Soo Choi), 조영제(Young Je Cho), 임성일(Sung Il Lim), 이선호(Seon Ho Lee), 손준호(Jun Ho Son), 최희진(Hee Jin Choi), 이희덕(Hee Duck Lee)
UCI I410-ECN-0102-2008-520-000744926

The production of bacterial protease and its characteristics were investigated with Bacillus subtilis globagii CCKS-118 which was isolated from Korean traditional soy sauce. The optimum culture condition of the strain for the production of alkaline protease was as follow : 2% soluble starch, 0.2℃ yeast extract, 0.1% (NH₄)₂SO₄, 0.2% MgSO₄ pH 7.5, 35℃ and 20hrs. The optimum pH and temperature for the enzyme action of alkaline protease producing Bacillus subtilis globigii CCKS-118 were pH 9.0 and 50℃, respectively. The enzyme was relatively stable at pH 6.0∼9.0 and at temperature below 40℃. The activity of the enzyme was inhibited by Hg^(2+) whereas Cu^(2+) gave rather activating effects on the enzyme activity. The enzyme was inhibited by phenylmethane-sulfonyl fluoride indicating serine protease metal ion group are required for the enzyme activity. Km value was 1.242×10^(-4)M, V_(max) value was 25.99 ㎍/min. This enzyme hydrolyzed casein more rapidly than the hemoglobin.

[자료제공 : 네이버학술정보]
×