닫기
18.97.14.83
18.97.14.83
close menu
SCIE SCOPUS
잠뇨로부터 질소함유 당물질 분리 및 glycosidase 에 대한 저해활성
Isolation of N-Containing Sugars from Silkworm Urine and Their Glycosidase Inhibitory Activities
송주경(Ju Kyung Song),정성현(Sung Hyun Chung)
UCI I410-ECN-0102-2009-510-008085111
* This article is free of use.

Glycosidase inhibitors from urine of Bombyx mori were isolated and their inhibitory activities on glycosidases were evaluated. Six compounds were isolated by using several ion exchange columns, and their chemical structures were identified by the physicochemical and spectral data. Compound IV, V and VI were identified as 1-deoxynojirimycin, fagomine and 1,4-dideoxy-1,4-imino-D-arabinitol, respectively. Among six compounds isolated, 1-deoxynojirimycin(IV) was the most potent inhibitor on α-glucosidase and β-galactosidase of rat intestine, and its inhibitory activities for trehalase and almond β-glucosidase were relatively weak. Compound V and VI retained a little inhibitory potency toward α-glucosidase and β-galactosidase. Compound II and III, however, have been found to have no effect on all glycosidases tested in this study.

[자료제공 : 네이버학술정보]
×