Purpose: This study was to examine the correlations among management of menopause, marital satisfaction, and quality of life in middle-aged women. Method: The sample was 158 middle-aged women who were 40-64 years. Data were collected from June 14 to July 10, 2003 using questionnaires and were analyzed by using the SPSS 10.0 PC+ program. Result: The level of marital satisfaction was related positively to the level of quality of life(r=.504, p<.01) and management of menopause(r=.315, p<.01). In addition, there were significant correlations between the level of quality of life and management of menopause(r=.251, p<.01). In stepwise multiple regression analysis, 25.9% of the variance in quality of life was explained by marital satisfaction. Conclusion: Marital satisfaction and management of menopause serve to improve the quality of life of middle-aged women. It is necessary to develop an effective intervention program to improve marital satisfaction and management of menopause.