Industry 4.0 has brought about significant changes in the roles of workers through the introduction of innovative technologies. In smart factory environments, workers are required to interact seamlessly with robots and automated systems, often utilizing equipment enhanced by Virtual Reality (VR) and Augmented Reality (AR) technologies. This study aims to systematically analyze recent research literature on monitoring the physical and mental states of workers in Industry 4.0 environments. Relevant literature was collected using the Web of Science database, employing a comprehensive keyword search strategy involving terms related to Industry 4.0 and health monitoring. The initial search yielded 1,708 documents, which were refined to 923 journal articles. The analysis was conducted using VOSviewer, a tool for visualizing bibliometric data. The study identified general trends in the publication years, countries of authors, and research fields. Keywords were clustered into four main areas: ‘Industry 4.0’, ‘Internet of Things’, ‘Machine Learning’, and ‘Monitoring’. The findings highlight that research on health monitoring of workers in Industry 4.0 is still emerging, with most studies focusing on using wearable devices to monitor mental and physical stress and risks. This study provides a foundational overview of the current state of research on health monitoring in Industry 4.0, emphasizing the need for continued exploration in this critical area to enhance worker well-being and productivity.