Indoor Air Quality is crucial in hospital projects to ensure the health and safety of patients, staff, and visitors. The research methodology comprises an comprehensive literature review, then a comprehensive questionnaire survey conducted among stakeholders involved in Vietnamese hospital projects. 15 variables were identified and categorized into four distinct groups, elucidating their influence on the adoption of advanced IAQ-enhancing technology. This study uses factor analysis, a mean score method and hypothesis test to analyze the factor result from the survey. two-step process, including an in-depth literature review and questionaire survey. The study's findings culminated in the ranking, examination, and categorization of these 15 variables, which were clustered into four essential categories: economic factors, design elements, governance strategies, and technical requirements. Additionally, the research explored viable solutions to improve indoor air quality in Vietnam's unique environmental context, examining the factors that impact the selection of such solutions. The study's outcomes yield practical recommendations for architects, engineers, and hospital administrators in enhancing IAQ within healthcare facilities. Furthermore, it presents a framework attuned to local environmental factors and building materials, contributing significantly to the existing body of knowledge on IAQ within hospital projects, particularly in the Vietnamese context.