Purpose: This study was done to identify the cultural capacity of college nursing students and the relationship of intercultural communication. Methods: The participants were 200 students in colleges of nursing from 6 universities in C city, who understood the purpose of the study and agreed to participate. Collected data were analyzed with t-test, ANOVA, correlation analysis, and stepwise regression analysis using SPSS/WIN 22.0. Results: Cultural sensitivities in this study (r=.372, p<.001), cultural knowledge (r=.399, p=.001), cultural awareness (r=.547, p<.001), and cultural technology (r=.550, p<.001) each showed a statistically significant correlation with intercultural communication skills. Conclusion: The results of this study show that reinforcement of the cultural and intercultural communication ability of college nursing students, in-depth exploration of the cultural area and religious inspection, cultural and professional backgrounds, assessment and consideration of cultural characteristics, nursing diagnosis, and health appropriate to the cultural background. It is suggested that education such as service provision should be conducted systematically.