Lane detection algorithms became a key factor of advance driver assistance system (ADAS), since the rapidly increasing of high-technology in vehicles. However, one common problem of these algorithms is their performance’s instability under various illumination conditions. We recognize a feasible complementation between image processing and color science to address the problem of lane marks detection on the road with different lighting conditions. We proposed a novel lane detection algorithm using the attributes of a uniform color space such as CIEL *C*h with the implementation of image processing techniques, that lead to positive results. We applied at the final stage Clustering to make more accurate our lane mark estimation. The experimental results show the effectiveness of our method with detection rate of 91.80%. Moreover, the algorithm performs satisfactory with changes in illumination due to our process with lightness (L*) and the color's property on CIEL *C*h.