This research is to design an effective prefetching method required for DRAM-PCM hybrid main memory systems especially used for big data applications and massive-scale computing environment. Conventional prefetchers perform well with regular memory access patterns. However, workloads such as graph processing show extremely irregular memory access characteristics and thus could not be prefetched accurately. Therefore, this research proposes an efficient dynamical prefetching algorithm based on the regression method. We have designed an intelligent prefetch engine that can identify the characteristics of the memory access sequences. It can perform regular, linear regression or polynomial regression predictive analysis based on the memory access sequences' characteristics, and dynamically determine the number of pages required for prefetching. Besides, we also present a DRAM-PCM hybrid memory structure, which can reduce the energy cost and solve the conventional DRAM memory system's thermal problem. Experiment result shows that the performance has increased by 40%, compared with the conventional DRAM memory structure.