연구배경: Subcutaneous negative pressure wound drains have been used to reduce wound complication rates in various surgical procedures. However, research on the benefits of subcutaneous drains on wound healing after ovarian cancer surgery is limited. The aim of this study was to assess the effects of subcutaneous negative pressure drains on wound healing after abdominal surgery for ovarian cancer. 대상 및 방법: Patients who underwent surgery with a midline incision for ovarian cancer between 2015 and 2019 were retrospectively examined. Patients were divided into two groups according to the presence (Group 1; n=99) or absence (Group 2; n=213) of subcutaneous wound drains. The primary endpoint was the incidence of wound complications within 8 weeks after abdominal surgery. The secondary endpoints were time interval from surgery to adjuvant chemotherapy and survival. 결과: Group 1 was older (mean, 58.5 vs. 55.4 years; P=0.020), had higher rates of previous abdominal surgery (66.7% vs. 47.9%; P=0.002), bowel surgery (47.5% vs. 34.3%; P=0.026), high surgical complexity score surgery (53.5% vs. 33.8%; P<0.001), compared with Group 2. A higher rate of clear wound healing (82.8% vs. 71.8%; P=0.036) and a lower rate of seroma formation (6.1% vs. 16.0%; P=0.015) were observed in Group 1, compared to Group 2. After multivariate analysis, subcutaneous wound drain placement was identified as an independent predictive factor for preventing wound complications (adjusted odds ratio, 0.43; 95% confidence interval, 0.21-0.87). Time interval from surgery to adjuvant treatment was significantly longer in patients with wound complications than in those with clear wound healing (mean, 23.6 vs. 19.2 days; P=0.003). Kaplan-Meier analysis, however, showed no significant differences in progression-free or overall survival between the two groups (P=0.353 and P=0.962, respectively). 결론: The prophylactic use of subcutaneous negative pressure drains after abdominal surgery for ovarian cancer significantly reduced the incidence of wound complications in this study.