Background: Pityriasis rosea is an idiopathic acute or subacute inflammatory disease with diverse subtypes and clinical courses. Objectives: The aim of this study was to investigate the clinical characteristics and courses of Korean pityriasis rosea patients. Methods: The demographic features, medical history, clinical characteristics, laboratory finding and treatment modalities of 80 pityriasis rosea patients are investigated. Results: The mean age of patients was 31.8 and 63.8% (51/80) of patients were female. The secondary lesion occurs 9.7 days after the primary lesion and lasts for 49.6 days on average. The primary lesions mainly occurred on the abdomen (18.8%, [15/80]) and 46.3% (37/80) of patients did not recognize the primary lesions. The secondary lesions mostly occur on the chest (77.5%, [62/80]) and abdomen (86.3%, [69/80]) with Christmas tree pattern (93.8%, [75/80]). 21 patients (26.3%) accompanied by prodromes and 52 patients (65.0%) accompanied by pruritus which is lower than expected. Most patients were treated by antihistamine (97.5%, [78/80]), topical calcineurin inhibitor (87.5%, [70/80]) and ultraviolet therapy (87.5%, [70/80]). Conclusion: Pityriasis rosea mainly occurred on the abdomen and lasted for about 7 weeks in Koreans. The treatment duration was longer in men, non-macular subtype regardless of age, primary lesion, prodromes,and itching severity. This study provides information about the clinical course of pityriasis rosea in Korean.