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Characteristics of bronchiectasis in patients with previous tuberculosis: a national database study in Korea
( Hayoung Choi ) , ( Yun Su Sim ) , ( Tae Rim Shin ) , ( Dong-gyu Kim ) , ( Dong Won Park ) , ( Tai Sun Park ) , ( Ji-yong Moon ) , ( Sang-heon Kim ) , ( Tae-hyung Kim ) , ( Jang Won Sohn ) , ( Ho Joo Yoon ) , ( Hyun Lee )
UCI I410-ECN-0102-2021-500-000607819
This article is 4 pages or less.
* This article is free of use.

Background: The characteristics of bronchiectasis and its clinical implications in patients with previous pulmonary tuberculosis have not been well elucidated using a nationally representative database. Methods: We compared respiratory symptoms, comorbidities, lung function, quality of life, and socioeconomic status in post-tuberculosis subjects with bronchiectasis versus those without bronchiectasis participating in the Korean National Health and Nutritional Examination Survey 2007-2009. Results: The prevalence of bronchiectasis was 2.6% (n = 35) in the 1,352 subjects with previous pulmonary tuberculosis. Bronchiectasis subjects showed lower body mass index (BMI) (21.9 vs. 23.4 kg/m2, P = 0.002) and higher asthma rate (26.8% vs. 4.5%, P < 0.001) compared with those without bronchiectasis. There were no significant intergroup differences in age, lung function, respiratory symptoms, family income, and education. However, compared with subjects without bronchiectasis, bronchiectasis subjects showed lower EuroQoL five dimensions (EQ-5D) index (0.86 vs. 0.93, P = 0.010), which denotes the poor quality of life. Among EQ-5D components, there was a significant difference in the anxiety/depression component (38.5 vs. 12.1, P = 0.002) between two groups. Bronchiectasis subjects were associated with lower EQ-5D index (difference = 0.077, 95% confidence interval: 0.002-0.151), as compared with those without bronchiectasis, using multivariable linear regression with adjustment for demographic characteristics, BMI, education, and family income. Conclusion: The prevalence of bronchiectasis was 2.6% in the subjects with previous pulmonary tuberculosis. Post-tuberculosis subjects with bronchiectasis had higher asthma rate and reduced quality of life than those without bronchiectasis.

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