Purpose : The purpose of this study was to determine the correlation between the self-esteem of health science college students and their empathy for others. Methods : A survey was administered to 448 students from the five departments of health science (Occupational Therapy, Physical Therapy, Dental Hygienics, Nursing, and Medical Administration) at a college located in Busan, South Korea, between September 28 and November 2, 2017. To measure their self-esteem and empathy for others, the Self-esteem Scale and the Korean Empathy Quotient (K-EQ) Scale were used. Results : There were statistically significant differences in social skills as a sub-item of empathy skills based on age and department, as well as in emotion as a sub-item of empathy skills based on sex. Self-esteem and all the items of empathy showed meaningful differences based on monthly expenses, while self-esteem and cognition as a sub-item of empathy skills displayed significant differences based on source of monthly income. Noteworthy differences were also found in self-esteem and emotion as a sub-item of empathy skills based on satisfaction with current school life. Self-esteem and empathy skills were shown to have a positive correlation. Conclusion : According to the results of this study, self-esteem and empathy skills had a statistically significant correlation. Further research is needed to investigate how health science college students can improve their understanding of themselves and their empathy for others.