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Learning curve could affect the surgical outcome of radical hysterectomy in cervical cancer: a single surgeon experience
( Seongmin Kim ) , ( Sumin Cho ) , ( Sanghoon Lee ) , ( Jae Yun Song )
UCI I410-ECN-0102-2021-500-000664907
This article is 4 pages or less.

Objective: Minimally invasive surgery has become essential technology in field of gynecologic malignancies including cervical cancer. But recent prospective study which showed poorer oncologic outcome following minimally invasive surgery led many surgeons to take a deep inspection for their practices. We reviewed our experience and evaluated the results of radical hysterectomy in patients with early stage cervical cancer. Methods: This retrospective study included patients with early stage cervical cancer (Ia1 ~ IIa2) who were treated with radical hysterectomy from May 2006 to Dec 2016. Patients were divided into three groups according to the approach of surgery: open laparotomy (ARH), laparoscopic radical hysterectomy (LRH), and robotic-assisted radical hysterectomy (RRH). The type of hysterectomy included Piver type II and III hysterectomy. Learning curves of each type of surgery were obtained using cumulative sum (CUSUM) method. The survivals were compared using Kaplan-Meier curves. Results: To analyze a learning curve of single surgeon, 89 patients were selected from whole population. Learning curves of each groups showed two distinct phases. The minimal cases required to achieve surgical improvement were 16 in ARH, 10 in LRH, and 13 in RRH. Progression-free survival and overall survival were not different between 3 groups (p=0.556 and p=0.273, respectively). But when the groups were stratified by the phases of the learning curves, the patients included in early phase showed poor PFS (p=0.045). This tendency was particularly significant in minimally invasive surgery (p=0.008). In patients even with tumor less than 2cm, the PFS after MIS was still poorer in patients during early phase(p=0.016). Conclusion: The learning curve could significantly affect the oncologic outcome in minimally invasive radical hysterectomy. This tendency was also observed even in patients with small tumor size. Enough experience is necessary to improve surgical outcome of MIS. Further, a prospective randomized study regarding sufficient surgical competence is necessary for elaborate analysis of feasibility of minimally invasive radical hysterectomy in cervical cancer.

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