The National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) has provided education and guidance for decades on the management of dyslipidemia. Its third report (ATP III) was published 10 years ago. The new ATP IV guidelines are expected to be released this summer. The major focus of this version will be as follows. 1) Definition of the very high and high risk patients 2) LDL target goal in secondary prevention 3) LDL treatment goal in patients with diabetes 4) Treatment for triglyceride and HDL-cholesterol 5) Clinical usefulness of non-conventional CV risk markers such as CRP, Lp(a) and carotid IMT.