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Metabolic syndrome in women with hypertension: Prevalence, and metabolic risk indicators
( Chonchanok Bunsuk ) , ( Wichai Arab ) , ( Naruebeth Koson ) , ( Wattana Vaythongkham ) , ( Jom Suwanno )
UCI I410-ECN-0102-2021-500-000673660
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Objective: We examined the (1) prevalence and (2) metabolic risk indicator of MetS among women with hypertension. Methods: We used secondary data analysis from two cross-sectional studied in women with hypertension (n = 582) attending primary care service in Thailand. MetS was stratified by using the American Heart Association/NHLBI criteria. Three of 5 metabolic risk indicators indicated MetS. Data were analyzed using descriptive statistic for prevalence of MetS and prevalence of metabolic indicators. We compared MetS indicators between women with MetS versus none MetS using t-test, Chi-square, and odds ratio (OR) with 95% confidential interval (95%CI). Results: Prevalence of MetS was 73.4%. Hypertensive women with 3-5 metabolic risk indicators were 30.4%, 28.7%, and 14.3%, respectively. Prevalence of each metabolic indicator is as following: all had hypertension (100%), high FPG or DM (55.2%), low HDL (55.2%), high TG (39.5%), and over WC (75.4%). Hypertensive women with MetS were more likely had higher DBP (p < 0.05), FPG (p < 0.0001), triglyceride (p < 0.0001),and waist circumference (p < 0.0001), while they had lower HDL (p < 0.0001), compared to none MetS. Systolic blood pressure of those with MetS and none MetS were not significantly difference (p = 0.942). Compared to non MetS group, women with MetS had significantly increment metabolic risk indicator on FPG or DM (OR 8.91, 95%CI 5.69-13.94), HDL (OR 13.25, 95%CI 8.13-21.61), triglyceride (OR 27.40, 95CI 11.85-63.34), and waist circumference (OR 9.77, 95%CI 6.35-15.01). Furthermore, increment risk of MetS was also found in those hypertensive women with overweight (OR 3.93, 95%CI 2.66-5.82) as compared to normal weight, and those with obesity (OR 3.33, 95%CI 2.25-4.93) as compared to none obesity. Conclusion: Our study has shown the high prevalence of MetS in women with hypertension. Approximately two-third of hypertensive women had at least 3 metabolic risk indicators. Women with hypertension may increment risk of overall type of cardiovascular disease if they had MetS.

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