Objective： Type 2 diabetes (T2D) has a high prevalence worldwide and is one of the leading cause of death. Lifestyle modification is essential in controlling T2D. Recently, mobile health (mHealth) technology has become a powerful platform which can promote behavior modification through tracing users’ daily activities. We evaluated the efficacy of smartphone-based glucose monitoring compared to conventional care. Methods： This is a pilot study for randomized controlled trial of 12 weeks for patients with T2D with and without smartphone-based intervention. The efficacy is defined as achievement of the target glycated hemoglobin (HbAlc < 6.5%). The smartphone-based care group were instructed to use Noom application and CareSens N NFC. Noom provides the calculator for daily calorie uptake and records the amount of daily physical activities. Self-measured blood glucose information was transmitted to the smartphone via a near-field communication technology. All participants completed the summary of diabetes self-care activities (SDSCA) questionnaire. Results: Twenty patients were randomly assigned to each arm. 17 patients of smartphone-care group and 18 patients of conventional care group were completed the trial. There was no significant difference in the baseline HbAlc between the two groups (8.5 ± 2.6 % vs. 9.1 ± 1.9，P 0.489). In smartphone-care group, more patients had less than 6.5% HbAlc at week 12 compared with conventional care group (8/17，47.1% vs. 2/16，11.1%, = 0.019). In both groups, SDSCA scores excluding the exercise item showed overall improvement (general diet, 1.4 ±2.0 to 2.6 ± 2.3 vs. 0.4 ± 1.1 to 1.8 ± 2.2; specific diet, 3.8 ± 0.7 to 3.8 ± 1.3 vs. 2.6 ± 1.9 vs. 3.8 ± 1.4; blood glucose test, 3.3 ± 2.8 to 4.9 ± 2.3 vs. 1.0 ± 2.2 to 4.7 ± 2.3; foot care, 1.5 ± 1.6 to 3.6 ± 2.8 vs. 1.4 ± 1.9 to 6.1 ± 1.4, all P〈 0.05). Conclusion： This pilot suggest smartphone-based care improves adherence and glucose control compared with conventional care. Smartphone-based diabetes care is expected to become a useful tool for integrated and intensified diabetes management practically.