Objective: To assess the spectrum of different parameters of renal function test in pre-diabetic and diabetic cases along with the correlation of fasting and postprandial blood glucose level with HbA1c in diabetic patient.
Methods: A cross sectional study was carried out in patient visiting OPD of Patan Hospital
Results: Out of 99 patients, 33.3% (n = 33) has normal blood sugar level whereas 19.1% (n = 19) were diagnosed as pre-diabetic or hyperglycemic. 47.6% (n = 47) were diagnosed as diabetic. Diabetic cases were seen to be predominant in female (n = 26) and at age group above 30 years. Few cases of diabetic, 14.8%(n = 7) were also seen at the age group of 18 -28yrs. HbA1c was seen to be better correlated with fasting plasma glucose (FPG) as compared to postprandial plasma glucose (PPG) (r = 0.803, r = 0.796 respectively at p < 0.01). Regarding Renal Function test, the urea level was found to be slightly higher in pre- diabetic patient (52.6 ± 15.2) than diabetic one (40.2 ± 10.5). Similar pattern was also seen for creatinine level (0.76 ± 0.44, 0.75 ± 0.44 respectively). Sodium level was found to be higher in pre- diabetic (136.37 ± 3.6) compared to diabetic(131.57 ± 2.8) (p < 0.01) but the value may be influenced by other confounding factors
Conclusion: Our study revealed that younger ones are also at risk of developing diabetes. Fasting plasma glucose level can be better indicator to monitor the glycemic level where HbA1c is not feasible. The pre-diabetic group are also at the high risk of having impairment in renal function. So, pre-diabetic patients should also be screened for RFT if feasible.