The purpose of this study was to investigate the effects of megavitamin E supplementation on changes of serum components and cardiopulmonary Function. 1. The subjects of this study were 30 Rugby Football players of high school. And they were randomly assigned to three groups as follows : Supplemental gorups were ingested 400IU/day and 1000IU/day of d-αtocopherol during 60 days. Control group was ingested Placebo during 60 days. 2. The results were summarized as follows: 1) The values of serum α-Tocopherol were significantly(P<0.05) increased in 1000IU group after 60days comparing to the pretreatment levels, And these were decreased after post treatment. But, this was not significant difference. 2) The valves of serum Total Cholesterol were significantly(P<0.05) decreased in all groups after 60 days comparing to the pretreatment levels And. the values of serum HDL-C were significantly(P<0.05) increased in all groups after 60days comparing to the pretreatment levels. But, these results were not significant differences among three groups. 3) The values of serum Triglyceride were decreased in all groups after 30days and 60days comparing to the pretreatment levels. And, these were increased in all groups after post-treatment. But. these results were not significant differences between treatment groups and dosing times. 4) V˙O₂ max and All-out-time were significantly(P<0.05) increased in all groups after 60 days comparing to the pre treatment levels. And, these were decreased in all groups after post treatment. But, these results were not significant differences among 3 groups. 5) V˙Emax was significantly(P<0.05) in creased in 1000IU group after 60 days. And, this was decreased in 1000IU group after post treatment. But, these results were not significantly differences between 400IU group and 1000IU group. 6) HR at rest. HRmax. and RRmax were not significant differences between treatment groups and dosing times. In summary, serum HDL- Cholesterol was increased and V˙O₂max All-Out time. and V˙Emax were improved. But. these were not significant differences among treatment groups. And. the effects of training and psychological factor were not excepted in this study. Therefore. these results were unable to confirm the ergogenic effects of the megavitamin E to improve the cardiopulmonary function.