Lichen planus (LP), psoriasis and vitiligo are relatively common dermatologic disease. There have been several reviews about the coexistence of LP and vitiligo and co-occurrence of psoriasis and vitiligo. However, the literatures reporting co-occurrence and suggesting association of these three disease are rare. Herein, we report a case of concurrent oral LP, localized pustular psoriasis (LPP) and vitiligo in a single patient. A 52-year-old man presented with irritant, diffuse, white-colored, lace-like patches on the both oral mucosa for 3 months. He had been diagnosed with LPP on the palm and sole and vitiligo on the both hand dorsum and finger. He have been treated with alitretinoin for LPP and systemic steroid, cyclosporine and intralesional triamcinolone injection for vitiligo. While taking oral cyclosporine, the lesion of oral mucosa have been appeared. The tissue from oral lesion showed hyperkeratosis, saw-tooth appearance of rete ridges, liquefaction degeneration and lichenoid inflammatory infiltration along the dermal-epidermal junction. Based on the clinical and histological findings, he was diagnosed as oral LP with LPP and vitiligo. Although the pathogenesis of these diseases are still not well understood, it can be suggested that there is etiological background connecting three diseases. One of the hypotheses is increase in the production of proinflammatory molecules such as interleukin-1, 6 and 8.