Cutaneous nontuberculous mycobacteria (NTM) infections, mostly caused by rapidly growing mycobacterium (RGM), have been primarily reported following medical procedures or penetrating injury. Soft tissue and skin infections by NTM show variations in clinical presentation such as ulcerations, plaques, papules and nodules, which may cause delays in diagnosis. As Mycobacterium massiliense is a recently identified RGM species belonging to Mycobaterium abscessus complex, it is rarely reported in the general population. A healthy 50-year-old woman visited our department with erythematous nodules on the dorsum of right hand and right forearm that had appeared 4 months ago. She complained no tenderness and itching sensation on the lesion. She had worked as a body polisher for 10 years but denied any history of trauma. Cutaneous NTM infections, cutaneous deep fungal infections and granuloma annulare were considered as differential diagnoses. The skin biopsy revealed granulomatous inflammation with neutrophilic micro-abscesses and multinucleated giant cells in the dermis. NTM was detected in the tissue culture and M. massiliense was finally identified by culture. Based on the antibiotic susceptibility test result, the patient was treated with clarithromycin for 4 months showing a successful response to the treatment. Herein we present a rare case of cutaneous M. massiliense infections that would not be attributed to a prior invasive procedure.