A 23-year-old female presented with multiple yellowish pustules on face, neck and both forearms occurred after accidental contact with oleylamine. Although the patient irrigated the wound immediately, pustules occured several hours later. Laboratory findings revealed a C-reactive protein level of 2.34mg/dL and bacteria did not grow in bacterial culture from pustules. Histopathologic examination revealed epidermal necrolysis with neutrophils and eosinophils infiltration accompanied by pustule formation. Based on these clinical and histopathological findings, she was diagnosed with pustular contact dermatitis. Oral prednisolone 10mg, cephradine 1000 mg for 2 weeks and topical methylprednisolone was applied. The lesions improved with only slight pigmentation within several weeks. We believe that the chronological correlation and clinical aspect support the diagnosis of an oleylamine-induced contact dermatitis. The pustulation of the skin is believed to be caused by irritancy or delayed hypersensitivity. Oleylamine is organic compound mainly used as a surfactant, and known to cause skin corrosion and severe eye damage. Pustular allergic or irritant contact dermatitis has been reported previously due to croton oil, merbromine, fluorine and minoxidil. But there was no case that pustular contact dermatitis triggered by oleylamine. Herein, we report the first case of oleylamineinduced pustular contact dermatitis.