Objective: This research aims to analyze the correlation of onset and glycemic control to macrovascular and microvascular complications in T2DM patients at Ragab Begawe Caram Hospital, Mesuji Regency. Methods: This research is an observational study conducted at RSUD Mesuji Regency in July 2018 to June 2019. Type 2 DM patients were diagnosed according to clinical features and blood sugar test on research subjects. Patient interview, physical examination and laboratory were performed on the internal medicine outpatient clinic. Data was collected and analyzed using statistics. Results: Research subjects involve 98 patients, 69.39% female, mean age distribution of 54 years, mean DM onset of 3.6 years. There were 19 T2DM patients with macrovascular complication (19%) and 27 patients with microvascular complication (27%). Macrovascular complication consists of CVD (8.2%), PAD (6.1%) and CAD (8.2%) while microvascular complication consists of nephropathy (11.2%), neuropathy (26.5%) and retinopathy (9.2%). Average onset on patients with macrovascular complication versus patients without macrovascular complication is 3.36 versus 3.69 years (p < 0.525). While the average onset of patients with microvascular complication versus patients without microvascular complication is 3.48 versus 3.69 years (p < 0.588). Based on glycemic control, uncontrolled vs controlled T2DM patients show macrovascular complications of 42% vs 58% (p < 0.793) and microvascular complications of 44% vs 56% (p < 0.486). Conclusion: This reseach shows no significance correlation of onset and glycemic control to macrovascular and microvascular complications in T2DM patients at Ragab Begawe Caram Hospital, Mesuji Regency.