Objective: We compare the risk of peripheral arterial disease in patients with and without type 2 diabetes mellitus Methods: The study was cross-sectional; data collection was performed about five months period, from October 2017 to March 2018. In this study 55 subjects with type 2 diabetes mellitus and 55 subjects without type 2 diabetes mellitus were randomly selected from the list of inpatients attending the Darkhan General Hospital, Darkhan-Uul province, Mongolia. The inclusion criteria were subjects who were diagnosed with type 2 DM according to World Health Organization criteria. Ankle brachial index was measured by each subjects. Results: In patients with T2DM the mean known duration, mean HbA1c were 6.2 ± 3.71years, 10.31 ± 2.46% respectively. Patients had reasonably poor-controlled diabetes with a mean HbA1c of 10.31±2.46% and a mean fasting plasma glucose of 12.57 ± 4.42 mmol/L. With T2DM patients weight, body mass index, waist circumference, fasting venous glucose had significantly higher than without T2DM subjects (p < 0.05). Among 55 patients with T2DM, 10 (18.1%) patients were ABI < 0.9, whereas only 1 patient among 55 patients without T2DM were ABI < 0.9 (OR= 12.22, CI:1.5-99.12, p = 0.034). Smoking, sex, known duration, cholesterol level, triglyceride level and HbA1c were no significance difference between patients with and without peripheral arterial disease in T2DM (p > 0.05). Serum creatinine level were patients with and without peripheral arterial disease 83.80 ± 21.8 μmol/l and 65.09 ± 18.20 μmol/l respectively (p = 0.006). Conclusion: The present study found peripheral arterial disease was significantly higher in patients with T2DM than patients without T2DM. Creatinine level was significantly and independently associated with abnormal ankle brachial index in subjects with type 2 diabetes mellitus.