Under the leadership of the CCP, several agencies and institutions have been currently involved in the anti-corruption campaign in the PRC. Among them, the Central Commission for Discipline Inspection (CCDI) is one of the most important organizations. The CCDI is an organization run under the National Congress of the Communist Party of China and was originally charged with rooting out corruption and malfeasance among party cadres. However, as the Ministry of Supervision was incorporated into the CCDI in 1993, and as the CCDI was authorized to set up the Central Leading Small Group for the anti-corruption campaign in 2002, the CCDI has been emerging as the core of the core agencies in the anti-corruption campaign in the PRC. This article is to look into the history, organizations and functions of the CCDI in Chapter II, and to inquire its relations with other institutions, such as the Politics and Law Commission (PLC) of the CCP, the Ministry of Public Security, the People's Procuratorate, the People's Court in Chapter III. In conclusion, this article confirms that the Politburo Standing Committee of the CCP controls the anti-corruption campaign in all sectors, and then to investigate and schematize how the CCDI leads the campaign as a mechanism of the leadership of the CCP.