Objectives: The purpose of this research was to determine the effects of interpersonal caring program on mental health among some university students. Methods: For this research, a non-synchronized quasi-experimental model including nonequivalent experimental and control group was used. Interpersonal caring program for the university students was composed of intensive program (8 hours). The experimental group was made up of 18 students and the control group was made up of 23 students. The data were collected from November 25 to December 17, 2010 and the collected data were analysed by the SPSS/Win 18.0 program. Results: Interpersonal caring program was effective for depression, anxiety, hostility and phobic anxiety. The results of this study indicate interpersonal caring program was effective in mental health among some university students. Conclusion: Therefore, interpersonal caring program can be actively utilized as a useful intervention program for university students.