Objective: This study is to grasp the exact states of female high school students’ knowledge about cervical cancer, human papillomavirus (HIV) vaccination-related health belief and vaccination rate, which was carried out in a descriptive form. Methods: This study was conducted on convenience samples, i.e., 404 female students at a high school located in a metropolitan city. The data were based on the self-report questionnaires made between September 1st and 30th, 2011. Results: On knowledge about cervical cancer, respondents scored low with 13.83 points. As regards HIV vaccination-related health belief, they showed a high level of perceived seriousness and benefit but showed a low level of perceived susceptibility and barriers. In particular, HIV vaccination rate stood at 2.2%. HIV vaccination-related health belief was higher in respondents who underwent gynecological treatments or have the family history of cervical cancer or were planning to receive the vaccination. In relation to general characteristics, the vaccination rate was higher in respondents who had ever visited obstetrics and gynecology clinics or had ever heard about cervical cancer. Conclusion: The foregoing results imply that the rise in HIV vaccination rate is premised on parents and children’s advancement in knowledge about cervical cancer, the increase in susceptibility to HIV vaccination and the lowering of perceived barriers. In this regard, there is the need to develop a realistic education program to meet the preceding needs.