The point-of-use water dispenser systems are widely used because of convenience in handling and demand for high-quality drinking water. The application has been increased recently in the public places such as department stores, universities and the rest areas in express ways. Improvement of water qualities by the dispenser systems was compared with tap water in this study. The tap water is supplied to the dispenser as the influent of the dispenser system. The twelve dispensers in the public places were used. The five dispensers used reverse osmosis as the main filter and other dispensers used various filters such as ultrafiltration, nanofiltration, and alumina filter. The water quality indicators for sanitation safety, i.e., turbidity and total coliforms, were evaluated. Other water qualities such as pH, residual chlorine, heterotrophic plate count (HPC), and total cell counts were also analyzed. By the point-of-use water dispenser, the turbidity, residual chlorine and pH were decreased and the HPC and total cell counts were increased. The t-test results revealed that the HPC of the tap waters were not significantly different from the treated waters but the total cell counts of the two groups were significantly different. The low pH of the RO filter treatment was also significantly different from the tap waters. This study will contribute to understand the role of the point-of-use water dispenser in improving water quality and to identify key water quality for the proper maintenance of the dispenser systems.