The purpose of this study is to identify the risk areas of HPAI in Korea and to analyze the feasibility of establishing an epidemic prevention zone. The geographical influences of HPAI are compared and analyzed by species, and the risk factors are analyzed based on classification of farm size, farm density, the characteristics of farms in the area of protection, geographical features, road networks and geographical characteristics by using the binomial logit model. For farms laying hens, commercial ducks, and parent duck stock, the higher the number of marrows, the higher the likelihood of the outbreak, while the lower the ratio of broiler chicks, the higher the probability of onset. Among the geographical features, migratory birds are shown to increase the probability of developing HPAI in all species. However, other variables show different results depending on poultry species.