Whether Islam and human rights are compatible, and if so, how they are compatible, has long been an important topic of religious sociology. This article aims to examine how Islam and human rights influence each other within the legal-political system of Malaysia, an Islamic state in Southeast Asia. It analyses how a civil society organisation Sisters in Islam, among other human rights groups in Malaysia, has become a reference group that promotes a modern form of Islam. I argue that Sisters in Islam has been successfully bridging the legal and theological approaches to Shari'a not only to protect human rights but also to present a moderate understanding of Islam that will be more suitable for multicultural Malaysia.