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A Case of Immunoglobulin A Pemphigus: Intraepidermal Neutrophilic Dermatosis Type
( Ji Hye Heo ) , ( Hee Seong Yoon ) , ( Si Hyub Lee ) , ( Seung Dohn Yeom ) , ( Lucia Kim ) , ( Soo-chan Kim ) , ( Ji Won Byun ) , ( Jeonghyun Shin ) , ( Gwang Seong Choi )
UCI I410-ECN-0102-2021-500-000286885
This article is 4 pages or less.

Immunoglobulin A (IgA) pemphigus is a rare variant of an autoimmune bullous disease with IgA antibodies. IgA pemphigus is divided into 2 major subtypes: the subcorneal pustular dermatosis (SPD) type and intraepidermal neutrophilic (IEN) dermatosis type. We documented a case of an 18-year-old woman with recurrent generalized blisters and pustules that were especially severe in the intertriginous areas. Some half-and-half blisters and coalesced pustules in an annular pattern with crusts were simultaneously observed. A biopsy specimen from one of the halfand- half blister lesions showed intraepidermal separation with multiple neutrophils. Direct immunofluorescence staining revealed lace-like intercellular deposition of IgA in the entire epidermis. IgA antibody deposits were also observed in the patient's serum. The eruptions cleared with systemic steroids and colchicine 0.6 mg for 1 week, and the patient remained in partial remission at the 8-month follow-up. Herein, we report a case of IEN-type IgA pemphigus, clinically mimicking SPD with half-and-half blisters. (Korean J Dermatol 2019;57(8):492∼495)

INTRODUCTION
CASE REPORT
DISCUSSION
ACKNOWLEDGMENT
CONFLICTS OF INTEREST
ORCID
REFERENCES
[자료제공 : 네이버학술정보]
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