목적: To evaluate the impact of FSH priming in IVM
방법: Meta-analysis was performed on the 4 selected studies in the statistical framework R using ‘meta’ package (fixed effect model: Inverse variance method). Subgroup analysis related to patient characteristic (‘PCOS’ and ‘Regular cycles’) was conducted. The outcome considered in this study was the rates of clinical pregnancy.
결과: The rates of clinical pregnancy were not different between ‘FSH priming’ group and ‘No priming’ group (overall: risk difference [RD] 0.04, 95% confidence interval [CI] -0.04-0.12; ‘PCOS’: RD 0.13, 95% CI -0.04-0.30; ‘Regular cycles’: RD 0.01, 95% CI -0.07-0.10).
결론: FSH priming shows no significant effect on clinical outcome.