목적: The aim of this study is to examine the pattern of chemotherapy and care in Korean ovarian cancer patients near the end-of-life.
방법: We designed a retrospective cohort composed of patients with ovarian cancer who received palliative chemotherapy at Severance Hospital. One hundred and thirty patients who died of cancer during last 5 years were evaluated in terms of the appropriateness of the cancer-care, including chemotherapy and hospice.
결과: Median overall survival was 1295 days. The median period between last chemotherapy and death was 101 days. Among the 130 patients, 75.3% received chemotherapy during the last 6 months of life and 26.2% during the last 2 months of life. Furthermore, 8 patients (6.2%) died within 2 weeks after receiving chemotherapy. The proportion who visited an emergency room (ER) more than once during the last months of life was 30%, and the average number of ER visits after a diagnosis of cancer was 1.94. The proportion of patients who received intensive care unit care within the last month was 5.4%. Mean numbers of regimens and cycles were 4.6(range, 2 to 12) and 22(range, 5 to 73). Although 64.6% of patients were referred to a hospice consultation, timing of referral was only media 44 days before death.
결론: Among patients who died of ovarian cancer, significant proportions were found to have received chemotherapy near the end-of-life and have visited ERs. Active discussion of hospice referral is needed in ovarian cancer patient during the end-of-life period in Korea.