목적: The aim of this study was to evaluate the prognostic significance of pre-treatment complete blood cell count (CBC), including white blood cell (WBC) differential, in epithelial ovarian cancer (EOC) patients with primary debulking surgery and to develop nomograms for platinum sensitivity, progression-free survival (PFS), and overall survival (OS). 방법: We retrospectively reviewed the records of 757 patients with EOC whose primary treatment consisted of surgical debulking and chemotherapy at Samsung Medical Center from 2002 to 2012. We subsequently created nomograms for platinum sensitivity, three-year PFS, and five-year OS as prediction models for prognostic variables including age, stage, grade, CA-125 level, residual disease after primary debulking surgery (PDS), and pre-treatment WBC differential counts. The models were then validated by ten-fold cross-validation (CV). 결과: In addition to stage and residual disease after PDS, which are known predictors, lymphocyte and monocyte count were found to be significant prognostic factors for platinum-sensitivity, platelet count for PFS, and neutrophil count for OS on multivariate analysis. The area under the curves (AUC) of platinum sensitivity, 3-year PFS, and 5-year OS calculated by the ten-fold CV procedure were 0.7405, 0.8159, and 0.815, respectively. 결론: Prognostic factors including pre-treatment CBC were used to develop nomograms for platinum sensitivity, 3-year PFS, and 5-year OS of patients with EOC. These nomograms can be used to better estimate individual outcomes.